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Dr. Fleisher's research focuses on perioperative cardiovascular risk assessment and reduction, evidence-based medicine, measurement of quality of care and health policy. For the past 10 years Drs. Fleisher and Silber have collaborated on numerous projects related to health services research and quality measurement in the Medicare population. Most recently, he has been studying the influence of culture and innovation on care delivery. He has received numerous federal, industry and foundation grants related to these subjects. He has authored over 300 articles, chapters and books.
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Lee A. Fleisher, MD, ML is Emeritus Professor of Anesthesiology and Critical Care at the University of Pennsylvania Perelman School of Medicine and continues to practice clinically. He is also the Founding Principal and CEO at Rubrum Advising, LLC. He serves as a Senior Advisor of the Bipartisan Policy Center and FasterCures of the Milken Institute, Senior Fellow of the Leonard Davis Institute of Health Economics and Visiting Fellow of the Duke-Margolis Center. He is a member of the Steering Committee of CHAI (Coalition of Health AI) and a member of the HITAC of the ONC. From July 2020-July 2023, he was the Chief Medical Officer and Director of the Center for Clinical Standards and Quality for the Centers for Medicare and Medicaid Services. In this capacity, he was responsible for executing all national clinical, quality, and safety standards for healthcare facilities and providers, as well as establishing coverage determinations for items and services that improve health outcomes for Medicare beneficiaries. From 2004 through July 2020, he was the Robert D. Dripps Professor and Chair of Anesthesiology and Critical Care and Professor of Medicine at the University of Pennsylvania. In 2007, he was elected to membership of the National Academy of Medicine of the National Academy of Sciences and served on Committees including the Board of Health Services of the NAM.
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Selected Publications
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Silber JH, Rosenbaum PR, Ross RN, Ludwig JM, Wang W, Niknam BA, Mukherjee N, Saynisch PA, Even-Shoshan O, Kelz RR, Fleisher LA.: Template Matching for Auditing Hospital Cost and Quality. Health Serv Res. 49: 1446-74, Mar 2014
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Weisberg R, Speck R, Fleisher LA: Fostering innovation in medicine: A conceptual framework for Medical Centers. Healthcare 2: 90-93, 2014.
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Onuoha OC, Arkoosh VA, Fleisher LA: “Choosing Wisely” in Anesthesiology: The Gap Between Evidence and Practice. JAMA Intern Med 174: 1391-5, 2014.
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Flynn DN, Speck RM, Mahmoud NN, David G, Fleisher LA.: The impact of complications following open colectomy on hospital finances: a retrospective cohort study. Perioper Med (Lond). 3: 1, Mar 2014.
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Glance LG, Fleisher LA.: Anesthesiologists and the Transformation of the Healthcare System: A Call to Action.
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Anesthesiology 120: 257-9, Feb 2014.
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Speck RM, Foster JJ, Mulher VA, Burke SV, Sullivan PG, Fleisher LA: Culture Change: Establishment of a Professionalism Committee Within an Academic Medical Center. Jt Comm J Qual Patient Saf 40: 161-7, April 2014.
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Fleisher LA, Trey B: Turning Mission-Based Academic-Department Leaders into a Leadership Team: A Case Study in Creating Value
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N Engl J Med Leading Healthcare Innovation HBR Insight Center 2013 Notes: http://images.nejm.org/editorial/supplementary/2013/hbr16-fleisher.pdf.
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Fleisher LA: Evidence based practice of Anesthesiology 3rd edition. Fleisher LA (eds.). Elsevier, 2013.
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Fleisher LA, Beckman J: Anesthesia and noncardiac surgery in patients with heart disease, 9th edition. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicien. Bonow RO, Mann DL, Zipes DP, Libby P (eds.). Elsevier, 2011.
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Fleisher LA, Roizen MF: Essence of Anesthesia Practice, 3rd edition. Elsevier
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Fleisher LA, Roizen MF (eds.). Elsevier, 2011.
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Last updated: 01/09/2025
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The Trustees of the University of Pennsylvania
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