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Daniel Herman Wolf, M.D., Ph.D.

Assistant Professor of Psychiatry
Attending Psychiatrist, Hospital of the University of Pennsylvania, Philadelphia, PA, University of Pennsylvania
Faculty Member, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine at the University of Pennsylvania
Staff Psychiatrist, Pennsylvania Hospital, Philadelphia, PA, University of Pennsylvania
Faculty Member, Center for Functional Neuroimaging (CfN), Perelman School of Medicine at the University of Pennsylvania
Staff Psychiatrist, Penn Presbyterian Medical Center, Philadelphia, PA, University of Pennsylvania
Faculty Member, Center for Biomedical Image Computing and Analytics (CBICA), Perelman School of Medicine at the University of Pennsylvania
Staff Psychiatrist, Chester County Hospital, West Chester, PA, University of Pennsylvania
Department: Psychiatry

Contact information
10 Gates Building
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-3692
Fax: 215-662-7903
Graduate Group Affiliations
Education:
A.B. (Biology)
Harvard College, 1992.
Ph.D. (Neuroscience)
Yale University School of Medicine, 2000.
M.D. (Medicine)
Yale University School of Medicine, 2001.
Post-Graduate Training
Intern in Transitional Medicine, Albert Einstein Medical Center, Philadelphia, PA, 2001-2002.
Resident in Psychiatry, McLean Hospital and Massachusetts General Hospital, Boston, MA, 2002-2005.
Chief Resident, Schizophrenia and Bipolar Disorders Program, McLean & Massachusetts General Hospitals, Boston, MA, 2004-2005.
Postdoctoral Fellow in Neuropsychiatry, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2005-2008.
Certifications
American Board of Psychiatry and Neurology (Psychiatry Diplomate), 2006.
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Description of Research Expertise

Key Words
psychosis, reward, motivation, negative symptoms, fMRI, pharmacological imaging

Research interests, techniques, and summary:
My overarching goal is to develop a translational research program to study the neural mechanisms of reward and motivation deficits in psychosis, depression, addiction, and other psychiatric disorders, and in those at risk for these disorders. By utilizing pharmacological challenges during functional neuroimaging, together with detailed clinical and behavioral assessments, I seek to relate these deficits to dysfunction in specific neural circuits, and develop better methods for assessing novel therapeutic interventions. I am also developing active collaborations with geneticists, animal researchers, and pharmaceutical industry scientists in order facilitate clinical translation of basic neuroscientific discoveries.

Description of Clinical Expertise

Dr. Wolf is a board-certified psychiatrist, with particular expertise in the treatment of adults with psychotic disorders.
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Last updated: 05/17/2017
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