John Y.k. Lee - Faculty Biosketch

John Y.K. Lee, M.D.

Professor of Neurosurgery at the Pennsylvania Hospital

Attending Neurosurgeon, Pennsylvania Hospital, University of Pennsylvania, PA

Attending Neurosurgeon, Hospital University of Pennsylvania, Philadelphia, PA

Medical Director, Penn Gamma Knife at Pennsylvania Hospital

Attending Neurosurgeon, Children's Hospital of Philadelphia, Philadelphia PA

Attending Neurosurgeon, Penn Presbyterian Medical Center

3 63

Department: Neurosurgery

4 1 b

46 Contact information
48

Department of Neurosurgery
19 801 Spruce Street
17 Spruce Building
2c 8th Floor
Philadelphia, PA 19106

2e Office: 215-829-6700
32 Fax: 215-829-6645
24

Email:
leejohn@pennmedicine.upenn.edu

4 3 3 1d

18 Publications
23

8e 6f

26 Search PubMed for articles c

3 2 29

Links
da Search PubMed for articles
db NBC10 Tracy Davidson Interview with Dr. Lee and Dr. O'Rourke about John McCain's diagnosis of glioblastoma
c2 Use of Three Dimensional Endoscopy in the Operating Room for Pituitary Surgery - Acromegaly
c

4 b 1f

13 Education:
21 9 B.S. 32 (Molecular Biophysics and Biochemistry) c
28 Yale University, 1994.
21 9 M.D. c
51 Rutgers - Robert Wood Johnson Medical School, New Jersey, 1998.
21 d M.S.C.E. 22 (Clinical Epidemiology) c
33 University of Pennsylvania, 2015.
c

3 3 21

1f Post-Graduate Training
24 57 Intern in Surgery, University of Pittsburgh, Pennsylvania, 1998-1999.
24 66 Resident in Neurological Surgery, University of Pittsburgh, Pennsylvania, 1999-2004.
24 6c Chief Resident in Neurological Surgery, University of Pittsburgh, Pennsylvania, 2004-2005.
24 3d Fellow (Functional Neurosurgery), Cleveland Clinic, Ohio 1b , 2005-2006.
c

3 25

17 Certifications
28 58 Gamma Knife Stereotactic Radiosurgery, University of Pittsburgh, 2005.
28 50 Board Certified, American Board of Neurological Surgery, 2009.
28 46 Cyberknife Stereotactic Radiosurgery, Accuray, 2011.
c

3 92 Permanent link
2 29

b6 > Perelman School of Medicine > Faculty > Details a

1e 1d

Description of Clinical Expertise

18d Dr. Lee has a passion for minimally invasive ways to treat brain and skull base tumors. This passion is expressed as a commitment to endoscopic approaches to remove pituitary, clival, acoustic neuromas and other skull-base tumors. Another expression of his interest in minimally invasive methods is his devotion to stereotactic radiosurgery, eg. "incision-less" brain surgery.
8
18c In addition to brain tumors, Dr. Lee is committed to the comprehensive treatment of patients with craniofacial neuralgias, including trigeminal neuralgia, glossopharyngeal neuralgia, and hemifacial spasm. Dr. Lee uses minimally invasive, fully endoscopic surgical procedures including microvascular decompression (Jannetta procedure) and stereotactic radiosurgery to cure these disorders.
1a 29

Selected Publications

f4 Lee JYK: Near Infrared Fluorescent Intraoperative Visualization of Meningiomas. Society of Neuro-Oncology - Meningiomas (Toronto, ON) June 2016 Notes: Poster Presentation.

251 Brastianos PK, Taylor-Weiner A, Manley PE, Jones RT, Dias-Santagata D, Thorner AR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L, Sunkavalli A, Shillingford N, Calicchio ML, Lidov HG, Taha H, Martinez-Lage M, Santi M, Storm PB, Lee JY, Palmer JN, Adappa ND, Scott RM, Dunn IF, Laws ER Jr, Stewart C, Ligon KL, Hoang MP, Van Hummelen P, Hahn WC, Louis DN, Resnick AC, Kieran MW, Getz G, Santagata S.: Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas. Nature Genetics 46(2): 161-5, Feb 2014.

102 Lee JYK, Finkelstein S, Hamilton RL, Rehka P, King Jr. JT, Omalu B: Loss of Heterozygosity Analysis of Benign, Atypical, and Anaplastic Meningiomas. Neurosurgery 55(5): 1163-1173, 2004.

11d Lee JYK, McInerney J, Niranjan A, Kondziolka D, Flickinger JF, Lunsford LD: Stereotactic Radiosurgery Providing Long Term Tumor Control in Cavernous Sinus Meningiomas. Journal of Neurosurgery 91(1): 65-72, 2002.

12d Lee JYK, Chen HI, Urban C, Hojat A, Church E, Xie SX, Farrar JT: Development and psychometric testing for the Brief Pain Inventory-Facial in patients with facial pain syndromes. Journal of Neurosurgery 113(3): 516-523, Sep 2010.

f2 Lee, JYK, Lang SS: Fully Endoscopic Cerebellopontine Angle Surgery: A Step-By-Step Guide for Microvascular Decompression and Tumor Resection. Endo:Press Tuttlingen 2013.

da Lee JYK, Bohman L, Bergsneider M: Contemporary Neurosurgical Techniques for Pituitary Tumor Resection. J Neurooncology 117(3): 437-444, May 2014.

150 Lee JYK, Sandhu S, Miller D, Solberg T, Dorsey JF, Alonso-Basanta M : Higher dose rate Gamma Knife radiosurgery may provide earlier and longer-lasting pain relief for patients with trigeminal neuralgia. Journal of Neurosurgery 123(4): 961-968, October 2015.

131 Lee JYK, O'Malley Jr, BW, Newman JG, Weinstein GS, Lega B, Diaz J, Grady MS: Transoral robotic surgery of craniocervical junction and atlantoaxial spine: a cadaveric study. Journal of Neurosurgery (Spine) 12(1): 13-18, January 2010.

2c

7 1d

2c back to top
26 Last updated: 07/15/2025
34 The Trustees of the University of Pennsylvania c