Pediatric Neurology; Neurology; Epilepsy; Neurogenetics; Epiepsy Neurogenetics; Developmental Delay; Autism Spectrum Disorder.
Epilepsy; Neurobiology of Disease; Physiology; Ion channels; Two-photon imaging.
Selected Publications
Hill, S.F., Goldberg, E.M.: A hit for base editing: Treatment of developmental epilepsy in a mouse model. Journal of Clinical Investigation 136(3): e200689, Feb 2026.
Hill, S.F., Enakhimion, E.A., Furlanis, E., Dai, M., Garcia, B.L., Willis, S., Tran, T., Fishell, G., Wang, Y., Goldberg, E.M.: Developmental dysregulation of chandelier cell excitability in a mouse model of Dravet Syndrome. bioRxiv 2026.02.02.702918, 2026 Notes: doi: https://doi.org/10.64898/2026.02.02.702918.
Clatot, J., Monnerie, H., Panzer, A., Platzer, K., Goldberg, E.M.: An epilepsy-associated KV3.1 potassium channel variant acts via dominant positive effect. J Gen Physiol 2026.
Sherer, M., Goldberg, E.M.: Flip of the Switch: Targeting GABA Dysregulation to Treat Nonseizure Comorbidities in Dravet Syndrome. Epilepsy Currents Nov 14 2025 Notes: Online ahead of print. doi: 10.1177/15357597251389967.
Hill, S.F., Liebergall, S.L., Wengert, E.R., Goldberg, E.M., Theyel, B.: Attenuated ectopic action potential firing in parvalbumin expressing interneurons in a mouse model of Dravet Syndrome. J Neurophysiol 133(6): 1692-1698, Jun 2025.
Edmondson, A.C., Budhraja, R., Xia, Z., Melendez-Perez, A., Cai, C., Radenkovic, S., Collins, A.M., Shiplett, E.J., Hill, S.F., Somarowthu, A., Dam, J., Pai, L.L., Santi, M., Kim, S., He, M., Goldberg, E.M., Kozicz, T., Morava, E., Pandey, A., Zhou, Z.: Novel mouse model reveals neurodevelopmental origin of PMM2-CDG brain pathology.
bioRxiv 2025.06.01.657261; doi: https://doi.org/10.1101/2025.06.01.657261
Jun 2025.
Rosenthal, Z., Joseph Majeski, J., Somarowthu, A., Quinn, D., Lindquist, D., Putt, M., Karaj, A., Favilla, C., Baker, W., Hosseini, G., Rodriguez, J., Cristancho, M., Sheline, Y., Shuttleworth, Abbott, C., Yodh, A., Goldberg, E.M.: Electroconvulsive therapy generates a hidden wave after seizure. Nat Commun 15((2_suppl)): 793S-822S, May 2025 Notes: doi.org/10.1101/2024.10.31.621357.
Furlanis, E., Dai, M., Garcia, B.L., Vergara, J., Pereira, A., Pelkey, K., Tran, T., Gorissen, B.L., Vlachos, A., Hairston, A., Huang, S., Dwivedi, D., Du, S., Wills, S., McMahon, J., Lee, A.T., Chang, E.F., Razzaq, T., Qazi, A., Vargish, G., Yuan, X., Caccavano, A., Hunt, S., Chittajallu, R., McLean, N., Hewit, L., Paranzino, E., Rice, H., Cummins, A.C., Plotnikova, A., Mohanty, A., Tangen, A.C., Shin, J.H., Azadi, R., Eldridge, M.A.G. Alvarez, V.A., Averbeck, B.B., Alyahyay, M., Vallejo, T.R., Soheib, M., Vattino, L.G., MacGregor, C.P., Banks, E., Olah, V.J., Naskar, S., Hill, S., Liebergall, S., Badiani, R., Hyde, L., Xu, Q., Allaway, K.C., Goldberg, E.M., Nowakowski, T.J., Lee, S., Takesian, A.E., Ibrahim, L.A., Iqbal, A., McBain, C.J., Dimidschstein, J., Fishell, G., Wang, Y.: An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes. Neuron
113(10): 1525-1547, May 2025.
Clatot, J., Thompson, C.H., Susan Sotardi, S., Jiang, J., Trivisano, M., Balestrini, S., Ward, I., Ginn, N., Guaragni, B., Malerba, L., Vakrinou, A., Sherer, M., Helbig, I., Somarowthu, A., Sisodiya, S.M., Ben-Shalom, R., Guerrini, R., Specchio, N., George, Jr., A.L., Goldberg, E.M.: Rare dysfunctional SCN2A variants are associated with malformation of cortical development. Epilepsia 66(3): 914-928, Mar 2025.
Wengert, E.R., Cheng, M.A., Liebergall, S.R., Markwalter, K.H., Hong, Y., Arias, L., Marsh, E.D., Zhang, X., Somarowthu, A., Goldberg, E.M.: Impaired excitability of fast-spiking neurons in a novel mouse model of KCNC1 epileptic encephalopathy. eLife 13(RP103784), December 2024 Notes: https://doi.org/10.7554/eLife.103784.1
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Last updated: 02/03/2026
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