Selected Publications
Zheng SL, Henry A, Cannie D, Lee M, Miller D, McGurk KA, Bond I, Xu X, Issa H, Francis C, De Marvao A, Theotokis PI, Buchan RJ, Speed D, Abner E, Adams L, Aragam KG, Ärnlöv J, Raja AA, Backman JD, Baksi J, Barton PJR, Biddinger KJ, Boersma E, Brandimarto J, Brunak S, Bundgaard H, Carey DJ, Charron P, Cook JP, Cook SA, Denaxas S, Deleuze JF, Doney AS, Elliott P, Erikstrup C, Esko T, Farber-Eger EH, Finan C, Garnier S, Ghouse J, Giedraitis V, Guðbjartsson DF, Haggerty CM, Halliday BP, Helgadottir A, Hemingway H, Hillege HL, Kardys I, Lind L, Lindgren CM, Lowery BD, Manisty C, Margulies KB, Moon JC, Mordi IR, Morley MP, Morris AD, Morris AP, Morton L, Noursadeghi M, Ostrowski SR, Owens AT, Palmer CNA, Pantazis A, Pedersen OBV, Prasad SK, Shekhar A, Smelser DT, Srinivasan S, Stefansson K, Sveinbjörnsson G, Syrris P, Tammesoo ML, Tayal U, Teder-Laving M, Thorgeirsson G, Thorsteinsdottir U, Tragante V, Trégouët DA, Treibel TA, Ullum H, Valdes AM, van Setten J, van Vugt M, Veluchamy A, Verschuren WMM, Villard E, Yang Y; COVIDsortium; DBDS Genomic Consortium; Estonian Biobank Research Team; HERMES Consortium; Asselbergs FW, Cappola TP, Dube MP, Dunn ME, Ellinor PT, Hingorani AD, Lang CC, Samani NJ, Shah SH, Smith JG, Vasan RS, O'Regan DP, Holm H, Noseda M, Wells Q, Ware JS, Lumbers RT: Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy. Nat Genet 56(12): 2646-2658, Dec 2024.
Selvaraj S, Patel S, Sauer AJ, McGarrah RW, Jones P, Kwee LC, Windsor SL, Ilkayeva O, Muehlbauer MJ, Newgard CB, Borlaug BA, Kitzman DW, Shah SJ, Margulies KB, Husain M, Inzucchi SE, McGuire DK, Lanfear DE, Javaheri A, Umpierrez G, Mentz RJ, Sharma K, Kosiborod MN, Shah SH: Metabolic Effects of the SGLT2 Inhibitor Dapagliflozin in Heart Failure Across the Spectrum of Ejection Fraction. Circ Heart Fail 17(11): e011980, Nov 2024.
Hill MC, Simonson B, Roselli C, Xiao L, Herndon CN, Chaffin M, Mantineo H, Atwa O, Bhasin H, Guedira Y, Bedi KC Jr, Margulies KB, Klattenhoff CA, Tucker NR, Ellinor PT: Large-scale single-nuclei profiling identifies role for ATRNL1 in atrial fibrillation. Nat Commun 15(1): 10002, Nov 2024.
Chaumont C, Peyster E, Siontis KC, Muser D, Kapa S, Markman TM, Pathak RK, Oraii A, Rodriguez-Queralto O, Anselme F, Margulies KB, Marchlinski FE, Frankel DS: Unipolar Voltage Mapping to Predict Recovery of Left Ventricular Ejection Fraction in Patients With Recent-Onset Nonischemic Cardiomyopathy. Circulation Nov 2024.
Boyle TA, Reza N, Hyman M, Supple G, See VY, Marzolf A, Hornsby N, de Feria A, Wang T, Margulies KB, Owens AT, Frankel DS: Atrial Fibrillation in Patients Receiving Mavacamten for Obstructive Hypertrophic Cardiomyopathy: Real-World Incidence, Management, and Outcomes. JACC Clin Electrophysiol S2405-500X(24), Nov 2024.
Doan KV, Luongo TS, Ts'olo TT, Lee WD, Frederick DW, Mukherjee S, Adzika GK, Perry CE, Gaspar RB, Walker N, Blair MC, Bye N, Davis JG, Holman CD, Chu Q, Wang L, Rabinowitz JD, Kelly DP, Cappola TP, Margulies KB, Baur JA: Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics. Nat Cardiovasc Res 3(10): 1236-1248, Oct 2024.
Lu F, Liou C, Ma Q, Wu Z, Xue B, Xia Y, Xia S, Trembley MA, Ponek A, Xie W, Shani K, Bortolin RH, Prondzynski M, Berkson P, Zhang X, Naya FJ, Bedi KC, Margulies KB, Zhang D, Parker KK, Pu WT: Virally delivered CMYA5 enhances the assembly of cardiac dyads. Nat Biomed Eng Sep 2024.
Meddeb M, Koleini N, Binek A, Keykhaei M, Darehgazani R, Kwon S, Aboaf C, Margulies KB, Bedi KC Jr, Lehar M, Sharma K, Hahn VS, Van Eyk JE, Drachenberg CI, Kass DA: Myocardial ultrastructure of human heart failure with preserved ejection fraction. Nat Cardiovasc Res 3(8): 907-914, Aug 2024.
Eaton DM, Lee BW, Caporizzo MA, Iyengar A, Chen CY, Uchida K, Marcellin G, Lannay Y, Vite A, Bedi KC Jr, Brady CF, Smolyak JN, Meldrum D, Dominic J, Weingarten N, Patel M, Belec A, Hached K, Atluri P, Van Der Laan S, Prosser BL, Margulies KB: Vasohibin inhibition improves myocardial relaxation in a rat model of heart failure with preserved ejection fraction. Sci Transl Med 16(756): eadm8842, Jul 2024.
Lazaropoulos MP, Gibb AA, Chapski DJ, Nair AA, Reiter AN, Roy R, Eaton DM, Bedi KC Jr, Margulies KB, Wellen KE, Estarás C, Vondriska TM, Elrod JW. : Nuclear ATP-citrate lyase regulates chromatin-dependent activation and maintenance of the myofibroblast gene program. Nat Cardiovasc Res 3(7): 869-882, Jul 2024.
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Last updated: 12/12/2024
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