Arndt Siekmann

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Associate Professor of Cell and Developmental Biology
Department: Cell and Developmental Biology

Contact information
1114 Biomedical Research Building II/III
421 Curie Boulevard
Philadelphia, PA 19104
Office: 215-898-7805
Graduate Group Affiliations
Education:
BS (Biology)
Albert-Ludwigs-Universität Freiburg, 2000.
PhD (Molecular Cell Biology and Genetics)
Max Planck Institute, 2004.
Post-Graduate Training
Postdoctoral Fellow, University of Massachusetts Medical School , 2005-2008.
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Selected Publications

Gao P, Chen C, Howell ED, Li Y, Tober J, Uzun Y, He B, Gao L, Zhu Q, Siekmann AF, Speck NA, Tan K: Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells. Genes and Development 34: 950, June 2020.

Santoro MM, Beltrame M, Panáková D, Siekmann AF, Tiso N, Venero Galanternik M, Jung HM, Weinstein BM: Advantages and Challenges of Cardiovascular and Lymphatic Studies in Zebrafish Research. Frontiers in Cell and Developmental Biology(7), 89, May 2019.

Red-Horse Kristy, Siekmann Arndt F: Veins and Arteries Build Hierarchical Branching Patterns Differently: Bottom-Up versus Top-Down. BioEssays : news and reviews in molecular, cellular and developmental biology 41(3): e1800198, Mar 2019.

Bondareva Olga, Tsaryk Roman, Bojovic Vesna, Odenthal-Schnittler Maria, Siekmann Arndt F, Schnittler Hans-J: Identification of atheroprone shear stress responsive regulatory elements in endothelial cells. Cardiovascular research Feb 2019.

Benedito, Rui and Siekmann, Arndt Friedrich: The European Society of Cardiology (ESC) textbook of Cardiovascular Biology. Blood vessel differentiation and growth. Perez-Pomares, Jose and Kelly, Robert (eds.). Oxford University Press, ISBN: 9780198757269, October 2018.

Caporali Andrea, Bäck Magnus, Daemen Mat J, Hoefer Imo E, Jones Elizabeth A, Lutgens Esther, Matter Christian M, Bochaton-Piallat Marie-Luce, Siekmann Arndt F, Sluimer Judith C, Steffens Sabine, Tuñón José, Vindis Cecile, Wentzel Jolanda J, Ylä-Herttuala Seppo, Evans Paul C: Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working group on Atherosclerosis and Vascular Biology. Cardiovascular research 114(11): [Epub ahead of print] Jul 2018.

Siekmann Arndt F: Coronary artery development, one cell at a time. Nature 559(7714): 335-336, Jul 2018.

Sugden Wade W, Siekmann Arndt F: Endothelial cell biology of Endoglin in hereditary hemorrhagic telangiectasia. Current opinion in hematology 25(3): 237-244, May 2018.

Hasan Sana S, Tsaryk Roman, Lange Martin, Wisniewski Laura, Moore John C, Lawson Nathan D, Wojciechowska Karolina, Schnittler Hans, Siekmann Arndt F: Endothelial Notch signalling limits angiogenesis via control of artery formation. Nature cell biology 19(8): 928-940, Aug 2017.

Sugden Wade W, Meissner Robert, Aegerter-Wilmsen Tinri, Tsaryk Roman, Leonard Elvin V, Bussmann Jeroen, Hamm Mailin J, Herzog Wiebke, Jin Yi, Jakobsson Lars, Denz Cornelia, Siekmann Arndt F: Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues. Nature cell biology 19(6): 653-665, Jun 2017.

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Last updated: 08/10/2021
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