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Denis Hadjiliadis, MD, MHS, PhD

Paul F. Harron, Jr. Professor
Director, Adult Cystic Fibrosis Program, University of Pennsylvania
Co-Director, Cystic Fibrosis Program, Perelman School of Medicine, University of Pennsylvania
Department: Medicine

Contact information
Hospital of the University of Pennsylvania
3400 Spruce Street
9031A Floor, West Gates Building
Philadelphia, PA 19104
Office: 215-662-4202
Fax: 215-614-0869
Education:
(Chemical Engineering (B.Eng; 2 years completed))
Faculty of Engineering, McGill University, Montreal, Canada, 1991.
MD (Doctor of Medicine Program)
Faculty of Medicine, University of Toronto, Canada, 1995.
MHS (Master’s of Health Sciences Program)
Duke University Medical Center, Durham, NC, 2001.
PhD (Ph.D in Medicine Program)
University of Ioannina, Ioannina, Greece, 2005.
Post-Graduate Training
Resident, Internal Medicine, Mayo Graduate School of Medicine, Rochester, MN, 1995-1998.
Fellow, Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, NC, 1998-2001.
Fellow, Lung Transplantation and Cystic Fibrosis, University of Toronto, Toronto, Ontario, Canada, 2001-2002.
Leading Success Program, University of Pennsylvania, 2012-2013.
Cystic Fibrosis and Lung Transplant Learning Leadership Consortium, Cystic Fibrosis Foundation, 2017-2020.
Fellow, Palliative Care, University of Pennsylvania; , 2020-2021.
Certifications
Diplomate, American Board of Internal Medicine, Internal Medicine (Recertified in Oct. 2008), 1998.
Royal College of Physicians of Canada, Internal Medicine, November 1999, 1999.
Diplomate, American Board of Internal Medicine, Pulmonary Disease (Recertified in April 2010 and November 2019), 2000.
Diplomate, American Board of Internal Medicine, Critical Care Medicine (Recertified in November 2011), 2001.
Royal College of Physicians of Canada, Respiratory Medicine, September 2002, 2002.
Pneumonology, Greek Ministry of Health, December 2004, 2004.
Board Eligible, American Board of Internal Medicine, Hospice and Palliative Care;, 2022.
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Description of Research Expertise

Cystic Fibrosis
Lung Transplantation
Bronchiectasis
Bronchiolitis Obliterans
Database Analysis

Description of Clinical Expertise

Cystic Fibrosis
Bronchiectasis
Lung Transplantation
CFTR-Related Disorder
Bronchiolitis Obliterans
Non-tuberculous mycobacteria
Palliative Care

Description of Other Expertise

Dr Hadjiliadis oversees one of the largest adult cystic fibrosis clinics in North America. He also has experience in the diagnosis and management of patients with bronchiectasis and CFTR-related disorder. In addition, he is a member of the Penn Lung Transplantation team and takes care of patients with end-stage lung disease requiring transplant. He is also a member Palliative Care team at the University of Pennsylvania

Multiple clinical trials in the above areas are available to patients at the University of Pennsylvania

Selected Publications

Mendizabal, Manuel Cywes, Claire Munoz, Nicolas Banker, Amay Bermudez, Christian Hadjiliadis, Denis Abt, Peter L: Have CFTR modulators changed the need for liver and lung transplantation among patients with cystic fibrosis? An analysis of the UNOS database. Liver transplantation November 2024.

Faerber, Jennifer A Kawut, Steven M Hadjiliadis, Denis Hong, Gina: The Real-World Effectiveness of Antifungals in People with Cystic Fibrosis and Aspergillus-Positive Cultures. Annals of American Thoracic Society October 2024.

Jain, Raksha Peng, Giselle Lee, MinJae Keller, Ashley Cosmich, Sophia Reddy, Sarthak West, Natalie E Kazmerski, Traci M Goralski, Jennifer L Flume, Patrick A Roe, Andrea H Hadjiliadis, Denis Uluer, Ahmet Mody, Sheila Ladores, Sigrid Taylor-Cousar, Jennifer L: Impact of Cystic Fibrosis Transmembrane Conductance Regulator Modulators on Maternal Outcomes During and After Pregnancy. Chest September 2024.

Luong, Me-Linh Nakamachi, Yoshiko Silveira, Fernanda P. Morrissey, Catherine O. Danziger-Isakov, Lara Verschuuren, Erik A. M. Wolfe, Cameron R. Hadjiliadis, Denis Chambers, Daniel C. Patel, Jignesh K. Dellgren, Goran So, Miranda Verleden, Geert M. Blumberg, Emily A. Vos, Robin Perch, Michael Holm, Are M. Mueller, Nicholas J. Chaparro, Cecilia Husain, Shahid: Management of infectious disease syndromes in thoracic organ transplants and mechanical circulatory device recipients: a Delphi panel. Transplant Infectious Disease 26(3), June 2024.

Sheikh, Saba Stefanovski, Darko Kilberg, Marissa J. Hadjiliadis, Denis Rubenstein, Ronald C. Rickels, Michael R. Kelly, Andrea: Early-phase insulin secretion during mixed-meal tolerance testing predicts β-cell function and secretory capacity in cystic fibrosis. FRONTIERS IN ENDOCRINOLOGY 15, February 2024.

Peng G; Taylor-Cousar JL; Lee M; Keller A; West NE; Kazmerski TM; Goralski JL; Aitken ML; Roe AH; Hadjiliadis D; Uluer A; Flume PA; Mody S; Bray LA; Jain R: Association between unplanned pregnancies and maternal exacerbations in cystic fibrosis. J Cyst Fibros. 22(5):796-803, 2023 Sep. 2023.

O'Dea AL; Feng R; Glaser LJ; Kubrak C; Rubenstein RC; Dorgan DJ; Hadjiliadis D; Kawut SM; Hong G: The Clinical Association between Aspergillus fumigatus and Respiratory Outcomes in Adolescents and Adults with Cystic Fibrosis. Annals of the American Thoracic Society. 20(7):984-992, 2023 07. 2023.

Hong G; Daniel SG; Lee JJ; Bittinger K; Glaser L; Mattei LM; Dorgan DJ; Hadjiliadis D; Kawut SM; Collman RG: Distinct community structures of the fungal microbiome and respiratory health in adults with cystic fibrosis. J Cyst Fibros. 22(4):636-643, 2023 07. 2023.

Kazmerski TM; Stransky OM; Lavage DR; Taylor-Cousar JL; Sawicki GS; Ladores SL; Godfrey EM; Aitken ML; Fields A; Sufian S; Jain M; Barto TL; Billings J; Hadjiliadis D; Jain R: Sexual and reproductive health experiences and care of adult women with cystic fibrosis. Journal of Cystic Fibrosis. 22(2):223-233, 2023 03. 2023.

Roe AH; Koelper N; McAllister A; Barnhart KT; Schreiber CA; Hadjiliadis D: Cervical mucus quality in females with and without cystic fibrosis. J Cyst Fibros. 22(5):804-805, 2023 Sep. 2023.

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Last updated: 11/19/2024
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