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1. Pulmonary hypertension: Diagnosis & management
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2. Consultative pulmonology & second opinions
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3. Cardiopulmonary exercise testing and the evaluation of unexplained dyspnea (shortness of breath)
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Dr. Fritz co-directs the multidisciplinary Dyspnea Program at Penn Presbyterian Medical Center.
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The Pulmonary Hypertension/Pulmonary Vascular Disease Program at the University of Pennsylvania is accredited as a Center of Comprehensive Care by the Pulmonary Hypertension Association (PHA).
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Pulmonary vascular disease: Therapeutics, outcomes
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Selected Publications
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Meservey A, Al-Naamani N, Minhas J, Fritz JS, Appleby D, Baudry G, Girerd N, Feng R, Kawut SM, Moutchia J: Renal dysfunction and outcomes in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: an individual participant data meta-analysis. Eur Respir J 66(2): 2402400, August 2025.
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McCarthy BE, Feng R, Torigian DA, Tong Y, Fritz JS, Minhas JK, Mazurek JA, Smith KA, Palevsky HI, Pugliese SC, Homer NZ, MacLean MR, Udupa JK, Al-Naamani N: Epicardial adipose tissue as an independent risk factor for mortality in pulmonary arterial hypertension. Chest 167(5): 1481, May 2025.
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Al-Naamani N, Prakash M, Pugliese S, Fritz JS, Smith KA, Palevsky HI, Compher C: Nutrition and diet quality in pulmonary arterial hypertension. Ann Am Thorac Soc 22(3): 462, Mar 2025.
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Minhas J, Moutchia J, Al-Naamani N, Mazurek JA, Holmes JH, Appleby D, Smith KA, Fritz JS, Pugliese SC, Palevsky HI, Kawut SM: Electrocardiographic abnormalities and their association with outcomes in randomized clinical trials of pulmonary arterial hypertension. Ann Am Thorac Soc 21(6): 858, June 2024.
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Pan HM, McClelland RL, Moutchia J, Appleby DH, Fritz JS, Holmes JH, Minhas J, Palevsky HI, Urbanowicz RJ, Kawut SM, Al-Naamani N: Heterogeneity of treatment effects by risk in pulmonary arterial hypertension. Eur Respir J 62(1): 2300190, July 2023.
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McCarthy BE, McClelland RL, Appleby DH, Moutchia JS, Minhas JK, Min J, Mazurek JA, Smith KA, Fritz JS, Pugliese SC, Urbanowicz RJ, Holmes JH, Palevsky HI, Kawut SM, Al-Naamani N: BMI and treatment response in patients with pulmonary arterial hypertension: a meta-analysis. Chest 162(2): 436-447, Aug 2022.
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Matura LA, Fargo JD, Boyle K, Fritz JS, Smith KA, Mazurek JA, Pinder D, Archer-Chicko CL, Palevsky HI, Pack AI, Sommers MS, Kawut SM: Symptom phenotypes in pulmonary arterial hypertension: the PAH "symptome" Pulm Circ 12: e12135, July 2022.
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Min J, Appleby DH, McClelland RL, Minhas J, Holmes JH, Urbanowicz RJ, Pugliese SC, Mazurek JA, Smith KA, Fritz JS, Palevsky HI, Suh JM, Al-Naamani N, Kawut SM
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: Secular and regional trends among pulmonary arterial hypertension clinical trial participants. Ann Am Thorac Soc 19(6): 952-961, Jun 2022.
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Goodman R, Chirinos JA, Ky B, Mazurek JA, Smith KA, Palevsky HI, Fritz JS, Pugliese SC, Kawut SM, Al-Naamani N: Systemic arterial properties in pulmonary hypertension. Pulm Circ 11(4): 1-3, Dec 2021.
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Herzig M, Khandhar S, Palevsky H, Fritz J, Mehta M, Matthai W: Intermediate-term outcomes for patients with submassive pulmonary embolism treated with catheter-directed thrombolysis. J Invasive Cardiol 33(12): E949-E953, Nov 2021.
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Last updated: 11/11/2025
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The Trustees of the University of Pennsylvania
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