faculty photo

Ebbing Lautenbach, MD, MPH, MSCE

Robert Austrian Professor
Department: Medicine

Contact information
712 Blockley Hall
Philadelphia, PA 19104-6073
Education:
BS (Chemistry and Psychology)
Calvin College, 1989.
MD (Medicine)
Columbia University College of Physicians and Surgeons, 1993.
MPH (General Public Health)
Columbia University, School of Public Health, 1993.
MSCE (Clinical Epidemiology)
University of Pennsylvania School of Medicine, Center for Clinical Epidemiology and Biostatistics, 2001.
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Description of CCEB Expertise

Dr. Lautenbach's research focuses on antibiotic use, antimicrobial resistance, outbreak investigation, and epidemiologic methods in the study of infectious diseases. This research focuses on various healthcare settings including acute care hospitals and long term care facilities. Dr. Lautenbach investigates the emergence and impact of extended-spectrum beta-lactamase (ESBL) resistance among gram-negative organisms, particularly how the dissemination of this resistance mechanism responds to manipulations of hospital antimicrobial formularies. Dr. Lautenbach also studies patterns of use of the fluoroquinolone antibiotics, as well as how such use patterns affect current trends in resistance to these agents. Finally, Dr. Lautenbach studies the epidemiology and transmission of methicillin-resistant Staphylococcus aureus (MRSA) in the community.

Description of Content-based Expertise

Infectious Diseases, Patient-Oriented Research, Pharmacoepidemiology, Public Health

Description of Methodology Expertise

Categorical Data, Multivariate Analysis

Selected Publications

Hostler CJ, Krishnan J, Parish A, Baroco A, Cooper P, Donceras O, Lautenbach E, Tolomeo P, Sansossio T, Santos CAQ, Schwartz D, Zhang H, Welbel S, Lokhnygina Y, Anderson D: CDC Prevention Epicenters Program. Postoperative outcomes after receipt of ertapenem antimicrobial prophylaxis for colon surgery: a multicenter retrospective cohort study. Infect Control Hosp Epidemiol. doi: 10.1017/ice.2024.99 4(45): 1-6, October 2024.

Moore K, Lautenbach E, Blumberg EA, Han J, Lee DH, Clauss H, Hasz R, Bilker WB, Molnar E, Alimenti D, West S, Tolomeo P, Anesi JA: Impact of deceased organ donor marijuana use on donor culture positivity and solid organ transplant recipient outcomes. doi: 10.1016/j.ajt.2024.02.022 8(1): 1427-1439, August 2024.

Choi J, Thänert R, Reske KA, Nickel KB, Olsen MA, Hink T, Thänert A, Wallace MA, Wang B, Cass C, Barlet MH, Struttmann EL, Iqbal ZH, Sax SR, Fraser VJ, Baker AW, Foy KR, Williams B, Xu B, Capocci-Tolomeo P, Lautenbach E, Burnham CD, Dubberke ER, Dantas G, Kwon JH: CDC Prevention Epicenters Program. Gut microbiome correlates of recurrent urinary tract infection: a longitudinal, multi-center study EClinicalMedicine. doi: 10.1016/j.eclinm.2024.102490 26(71): 1024, April 2024.

Zhang HL, Perez R, Krishnan J, Lautenbach E, Anderson DJ.: Risk Factors for Recurrence of Community-Onset Urinary Tract Infections Caused by Extended-Spectrum Cephalosporin-Resistant Enterobacterales Open Forum Infect Dis. 10(12), Nov 2023.

Mannathoko N, Lautenbach E, Mosepele M, Otukile D, Sewawa K, Glaser L, Cressman L, Cowden L, Alby K, Jaskowiak-Barr A, Gross R, Mokomane M, Paganotti GM, Styczynski A, Smith RM, Snitkin E, Wan T, Bilker WB, Richard-Greenblatt M.J : Performance of CHROMagar ESBL media for the surveillance of extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) from rectal swabs in Botswana Med Microbiol. 72(11), Nov 2023.

Lautenbach E, Mosepele M, Smith RM, Styczynski A, Gross R, Cressman L, Jaskowiak-Barr A, Alby K, Glaser L, Richard-Greenblatt M, Cowden L, Sewawa K, Otukile D, Paganotti GM, Mokomane M, Bilker WB, Mannathoko N.: Risk Factors for Community Colonization With Extended-Spectrum Cephalosporin-Resistant Enterobacterales (ESCrE) in Botswana: An Antibiotic Resistance in Communities and Hospitals (ARCH) Study Clin Infect Dis. 77(Suppl 1): S89-S96, July 2023.

Zhang HL, Gontjes KJ, Han JH, Alby K, Lapp Z, Snitkin E, Goldstein EJC, Muldoon S, Tolomeo P, Lautenbach E.Infect : Characterization of resistance to newer antimicrobials among carbapenem-resistant Klebsiella pneumoniae in the post-acute-care setting. Control Hosp Epidemiol. 44(7): 1159-1162, July 2023.

Tsalik EL, Rouphael NG, Sadikot RT, Rodriguez-Barradas MC, McClain MT, Wilkins DM, Woods CW, Swamy GK, Walter EB, El Sahly HM, Keitel WA, Mulligan MJ, Tuyishimire B, Serti E, Hamasaki T, Evans SR, Ghazaryan V, Lee MS, Lautenbach E; TRAP-LRTI Study Group; Antibacterial Resistance Leadership Group : Efficacy and safety of azithromycin versus placebo to treat lower respiratory tract infections associated with low procalcitonin: a randomised, placebo-controlled, double-blind, non-inferiority trial. Lancet Infect Dis. 23(4): 484-495, Apr 2023.

Cotter CJ, Ferradas C, Ludwig S, Dalton K, Larsen J, Laucks D, Iverson SA, Baron P, Tolomeo PC, Brazil AM, Ferguson JM, Lautenbach E, Rankin SC, Morris DO, Davis : Risk factors for meticillin-resistant Staphylococcus aureus (MRSA) carriage in MRSA-exposed household pets. MF.Vet Dermatol. 34(1): 22-27, Feb 2023.

Anesi JA, Lautenbach E, Thom KA, Tamma PD, Blumberg EA, Alby K, Bilker WB, Werzen A, Ammazzalorso A, Tolomeo P, Omorogbe J, Pineles L, Han JH : Clinical Outcomes and Risk Factors for Carbapenem-resistant Enterobacterales Bloodstream Infection in Solid Organ Transplant Recipients. Transplantation 107(1): 254-263, Jan 2023.

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Last updated: 05/28/2025
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