Alexis Ogdie, MD, MSCE
Professor of Medicine (Rheumatology) at the Hospital of the University of Pennsylvania
Department: Medicine
Graduate Group Affiliations
Contact information
3400 Spruce Street
5 White Building
Hospital of the University of Pennsylvania
Philadelphia, PA 19104-4283
5 White Building
Hospital of the University of Pennsylvania
Philadelphia, PA 19104-4283
Office: 215-662-2454
Fax: 215-662-4500
Fax: 215-662-4500
Education:
BS
University of Minnesota, 2002.
MD
Georgetown University School of Medicine, 2006.
MSCE
University of Pennsylvania, 2012.
Permanent linkBS
University of Minnesota, 2002.
MD
Georgetown University School of Medicine, 2006.
MSCE
University of Pennsylvania, 2012.
Description of CCEB Expertise
Dr. Ogdie-Beatty’s research program focuses on pharmacoepidemiology and observational studies of psoriatic arthritis, an inflammatory arthritis with potentially devastating outcomes that affects around 30% of patients with psoriasis and approximately 500,000 Americans. The mission her program is to develop more effective therapeutic strategies for SpA by increasing the focus on meaningful, patient-centered outcomes, broadening the patient population studied, accelerating diagnosis, and developing and advancing methods for precision medicine strategies. To improve the quality of care available to patients with PsA, Dr. Ogdie-Beatty is leveraging the PsA clinic that she directs at the Hospital of the University of Pennsylvania to investigate methods of assessing the effectiveness of treatments for psoriatic disease within clinical practice. Dr. Ogdie-Beatty completed a Master of Science in Clinical Epidemiology in order to integrate pharmacoepidemiology and observational methodology into studies of inflammatory arthritis. As a result of this training, she is an expert in the use of large medical record databases, in particular The Health Improvement Network (THIN), to study disease outcomes in PsA.Selected Publications
Gladman DD, Eder L, Selmi C, Mease PJ, Ogdie A, Lozenski K, Adamson E, Sharaf M, Rampakakis E, Pina Vegas L, Coates LC.: Influence of Biological Sex on Participant Characteristics, Guselkumab Efficacy and Radiographic Progression in Active Psoriatic Arthritis: Post Hoc Analysis of Three Randomized Trials. Rheumatol Ther Dec 2025.Thrastardottir T, Bjornsson AH, Ogdie A, Hauksdottir A, Kristinsson SY, Gudbjornsson B, Love TJ; ICEBIO.: Antimicrobial Use and Serious Infections Among Patients With Psoriatic Arthritis After Initiating Tumor Necrosis Factor Inhibitors: A Nationwide Matched Cohort Study. J Rheumatol Dec 2025.
Ogdie A, Middaugh N, Blachley T, Bourgeois T, Ling YL, Mundayat R, Fallon L, Masri KR, Mease PJ.: Effectiveness of Tofacitinib in Patients with Psoriatic Arthritis Initiating Monotherapy Versus Combination Therapy: Results from the CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry. Rheumatol Ther Dec 2025.
Gossec L, Balanescu A, D'Agostino MA, Ogdie A, Sewerin P, Deng Y, Shi L, Sugimoto Y, Zhong S, Xing Y, Lippe R, Kishimoto M.: Efficacy of Risankizumab across distinct PsA phenotypes identified with machine learning analytics using data from biologic DMARD-Naïve patients in two phase 3 clinical trials. Arthritis Res Ther Nov 2025.
McInnes IB, Coates LC, Mease PJ, Ogdie A, Kavanaugh A, Eder L, Schett G, Kivitz A, McGonagle D, Brennan N, Godwood A, Cullen E, Reich K, Ritchlin CT, Merola JF.: Sonelokimab, an IL-17A/IL-17F-inhibiting nanobody for active psoriatic arthritis: a randomized, placebo-controlled phase 2 trial. Nat Med Oct 2025.
Landzberg E, Ogdie A, Yarnell C, Harhay MO, Yehya N.: Observational studies of early versus late salvage therapies in critical care exhibit intrinsic selection bias: two meta-analyses. Crit Care 29: 411, Sep 2025.
Armstrong AW, Mburu S, Gondo GC, Kornyeyeva E, Frade S, Ogdie A.: Patient Experiences with Psoriatic Disease in the USA: Results from the Psoriasis and Beyond Global Study. Drugs Real World Outcomes Aug 2025.
Mayer SE, Kluberg SA, Spence O, Oraichi D, Seifert H, Ali O, Yun H, Simon AL, Ko JS, Hugh C, Her M, Shattuck K, Jamal-Allial A, Djibo DA, Daniels K, Ma Q, McMahill-Walraven CN, Ogilvie RP, Palmsten K, Selvan M, Ziyadeh N, Ogdie A, George MD.: Effectiveness and safety of the recombinant zoster vaccine in adult patients with systemic lupus erythematosus: a claims-based retrospective cohort study in the USA. RMD Open 11: e005839, Aug 2025.
Wu A, Zhang A, Guo Y, Liu J, Yang DM, Chada LP, Ogdie A, Reddy SM, Gottlieb AB, Scher JU, Merola JF.: Comparative Risk of Infection and Prevalence of Combination Targeted Therapy in Psoriatic Arthritis. JAMA Dermatol Aug 2025.
Coates LC, Blanco R, Behrens F, Ogdie A, Van den Bosch F, Ranza R, Klionsky Y, Soliman AM, Chen M, Coombs D, Shi L, Urbanik JR, Iyile T, Lippe R, Gossec L.: Efficacy of risankizumab across GRAPPA domains in psoriatic arthritis: a pooled analysis of patients from the phase 3 KEEPsAKE 1 and 2 studies. RMD Open 11: e005522, Aug 2025.