Youwen You
Analytical Research and Forensics Coord., University of Pennsylvania
Equine Toxicology and Research Laboratory
Research Associate Professor of Equine Forensic Chemistry, University of Pennsylvania, School of Veterinary Medicine PA Equine Toxicology and Research Lab
Contact information
University of Pennsylvania
School of Veterinary Medicine
Pennsylvania Equine Toxicology and Research Lab
220 E. Rosedale Avenue
West Chester, PA 19382
School of Veterinary Medicine
Pennsylvania Equine Toxicology and Research Lab
220 E. Rosedale Avenue
West Chester, PA 19382
Office: 610-925-1930
Email:
ywyou@upenn.edu
ywyou@upenn.edu
Education:
B.S.
South China Agricultural University, 1991.
M.S.
Chinese Academy of Agricultural Sciences, 1997.
PhD
University of Wyoming, 2002.
Permanent linkB.S.
South China Agricultural University, 1991.
M.S.
Chinese Academy of Agricultural Sciences, 1997.
PhD
University of Wyoming, 2002.
Description of Clinical Expertise
Equine anti-doping control analysisDescription of Research Expertise
Equine forensic and anti-doping analysis; Equine drug metabolism, pharmacokinetics (DMPK) and toxicology; Development and validation of bioanalytical methods. High throughput analysis of drug and drug metabolites at low concentrations in complex biological matrices.Selected Publications
You, Y.W., J.R. Missanelli, R.M. Proctor, J.E. Haughan, M.A. Robinson: Simultaneous quantification and confirmation of oxycodone and its metabolites in equine urine using ultra-high performance liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 2024.You, Y.W., R.M. Proctor, J.E. Haughan, J.R. Missanelli, M.A. Robinson.: Use of liquid chromatography-tandem mass spectrometry to quantify and confirm fentanyl metabolite N-[1-(2-Phenethy-4-Piperidinyl)] Maloanilinic Acid in equine urine for doping control. J. Anal. Toxicol. 2023.
Haughan, J. E. Missanelli, J. R. You, Y. W. Stefanovski, D. Soma, L. R. Robinson, M. A.: Pharmacokinetics of glaucine after intravenous and oral administrations and detection of systemic aporphine alkaloids after ingestion of tulip poplar shavings in horses. J. Vet. Pharmacol. Ther. 2022.
You, Y.W., R.M. Proctor, K. Guo, X.Q. Li, E. Xue, F.Y. Guan, M.A. Robinson: Use of high resolution/accurate mass full scan/data-dependent acquisition for targeted/nontargeted screening in equine doping control. Anal. Methods. 2021.
Guan, F. Y. You, Y. W. Fay, S. Li, X. Q. Robinson, M. A.: Novel Algorithms for Comprehensive Untargeted Detection of Doping Agents in Biological Samples. Anal. Chem. 2021.
Robinson, M.A., D. Stefanovski, Y.W. You, R.C. Boston, L.R. Soma: Bayesian‐based withdrawal estimates using pharmacokinetic parameters for two capsaicinoid‐containing products administered to horses. J Vet Pharmacol Therap 2020.
Morgan, J., M.W. Ross, D.G. Levine, D. Stefanovski, Y.W. You, YW, M.A. Robinson, E.J. Davidson: Effects of acepromazine and xylazine on subjective and objective assessments of forelimb lameness. Equine Vet. J 2020.
Guan, F.Y., S. Fay, X.Q. Li, Y.W. You, M.A. Robinson: Identification of exvivo catabolites of peptides with doping potential in equine plasma by HILIC‐HRMS. Drug Test Anal 2020.
Guan, F.Y., Y.W. You, X.Q. Li, M.A. Robinson: A comprehensive approach to detecting multitudinous bioactive peptides in equine plasma and urine using hydrophilic interaction liquid chromatography coupled to high resolution mass spectrometry. Drug Test Anal 11: 1308-1325, 2019.
You, Y.W., F.Y. Guan, R. D'Ippolitoa, X.Q. Li, L.R. Soma, M.A. Robinson: High-throughput Racehorse Doping Control Analysis of 28 Amphetamine-type Stimulants in Equine Plasma Using Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry. Drug Test Anal 11: 441-454, 2019.