Emily Miedel
Associate Professor of Laboratory Animal Medicine, University of Pennsylvania School of Veterinary Medicine
Contact information
3800 Spruce Street, OVQ 177E
Philadelphia, PA 19104
Philadelphia, PA 19104
Office: 215-898-6467
Email:
emiedel@upenn.edu
emiedel@upenn.edu
Publications
Education:
B.S. (Business and Economics)
La Salle University, 2000.
V.M.D. (Veterinary Medicine)
University of Pennsylvania, 2007.
Permanent linkB.S. (Business and Economics)
La Salle University, 2000.
V.M.D. (Veterinary Medicine)
University of Pennsylvania, 2007.
Description of Clinical Expertise
Clinical interests include outbreak management in immune-deficient murine models, specifically containment and eradication of bacterial infections that threaten research model integrity. I also focus on model refinement and translational medicine models.Selected Publications
Miedel, E. L., Ragland, N. H., Slate, A. R., Engelman, R. W.: Persistent Corynebacterium bovis infectious hyperkeratotic dermatitis in immunocompetent epidermal-mutant dep/dep mice. Veterinary Pathology 57(4): 586-589, 2020.Wallace, C. K., Bell, S. E., LaTourette, P. C., 2nd, Miedel, E. M., Carty, A. J., Philips, B. H.: Suspected Anaphylactic Reaction to Ketamine in 3 Yucatan Swine (Sus scrofa). Comparative Medicine 69(5): 419-424, 2019.
Vedder, A. R., Miedel, E. L., Ragland, N. H., Balasis, M. E., Letson, C. T., Engelman, R. W., Padron, E.: Effects of Corynebacterium bovis on engraftment of patient-derived chronic-myelomonocytic leukemia cells in NSGS mice. Comparative Medicine 69(4): 276-282, 2019.
Rodriguez, I., Philips, B. H., Miedel, E. L., Bright, L. A., LaTourette Ii, P. C., Carty, A. J., Witschey, W. R., Gorman, R. C., Gorman Iii, J. H., Marx, J. O.: Hydromorphone-induced neurostimulation in a Yorkshire swine (Sus scrofa) after myocardial infarction surgery. J Am Assoc Lab Anim Sci 58(5): 601-605, 2019.
Ragland, N. H., Miedel, E. L., Engelman, R. W.: PCR prevalence of murine opportunistic microbes and their mitigation by using vaporized hydrogen peroxide. J Am Assoc Lab Anim Sci 58(2): 208-215, 2019.
Miedel, E. L., Ragland, N. H., Engelman, R. W.: Facility-wide eradication of Corynebacterium bovis by using PCR-validated vaporized hydrogen peroxide. J Am Assoc Lab Anim Sci 57(5): 465-476, 2018.
Misic, A. M., Miedel, E. L., Brice, A. K., Cole, S., Zhang, G. F., Dyer, C. D., Secreto, A., Smith, A. L., Danet-Desnoyers, G., Beiting, D. P.: Culture-independent profiling of the fecal microbiome to identify microbial species associated with a diarrheal outbreak in immunocompromised mice. Comparative Medicine 68(4): 261-268, 2018.
Ragland, N. H., Miedel, E. L., Gomez, J. M., Engelman, R. W.: Staphylococcus xylosus PCR-validated decontamination of murine individually ventilated cage racks and air handling units by using ''active-closed'' exposure to vaporized hydrogen peroxide. J Am Assoc Lab Anim Sci 56(6): 742-751, 2017.
Miedel, E. L., Brisson, B. K., Hamilton, T., Gleason, H., Swain, G. P., Lopas, L., Dopkin, D., Perosky, J. E., Kozloff, K. M., Hankenson, K. D., Volk, S. W.: Type III collagen modulates fracture callus bone formation and early remodeling. Journal of Orthopaedic Research 33(5): 675-84, 2015.
Miedel, Emily L., Hankenson, F. Claire: Biology and Diseases of Hamsters [Chapter 5] Laboratory Animal Medicine. Academic Press, Page: 209-245, 2015.
Burke, D., Dishowitz, M., Sweetwyne, M., Miedel, E., Hankenson, K. D., Kelly, D. J.: The role of oxygen as a regulator of stem cell fate during fracture repair in TSP2-null mice. Journal of Orthopaedic Research 31(10): 1585-96, 2013.
Miedel, E., Dishowitz, M. I., Myers, M. H., Dopkin, D., Yu, Y. Y., Miclau, T. S., Marcucio, R., Ahn, J., Hankenson, K. D.: Disruption of thrombospondin-2 accelerates ischemic fracture healing. Journal of Orthopaedic Research 31(6): 935-43, 2013.
Baran, S. W., Perret-Gentil, M. I., Johnson, E. J., Miedel, E. L., Kehler, J.: Rodent laparoscopy: refinement for rodent drug studies and model development, and monitoring of neoplastic, inflammatory and metabolic diseases. Laboratory Animals 45(4): 231-9, 2011.