Katrin Hinrichs
Chair, Department of Clinical Studies-New Bolton Center, University of Pennsylvania School of Veterinary Medicine
Harry Werner Endowed Professor of Equine Medicine, University of Pennsylvania School of Veterinary Medicine
Professor of Reproduction, University of Pennsylvania School of Veterinary Medicine
Contact information
Penn Vet New Bolton Center
382 W. Street Road
Kennett Square, PA 19348
382 W. Street Road
Kennett Square, PA 19348
Office: 610-925-6320
Email:
katrinh@vet.upenn.edu
katrinh@vet.upenn.edu
Publications
Education:
DVM (Veterinary Medicine-Equine Track)
University of California-Davis, 1978.
PhD (Biomedical Graduate Group)
University of Pennsylvania, 1988.
Permanent linkDVM (Veterinary Medicine-Equine Track)
University of California-Davis, 1978.
PhD (Biomedical Graduate Group)
University of Pennsylvania, 1988.
Description of Clinical Expertise
Equine reproduction, Reproductive medicineDescription of Research Expertise
Dr. Hinrichs' research efforts include diagnostic and clinical health areas, such as:* Equine reproductive management
* Reproductive medicine
* Embryo transfer
* Reproductive surgery
Past research includes:
• Use of time-lapse imaging to evaluate morphokinetics of in vitro equine blastocyst development
• Effect of intra-ovarian injection of mesenchymal stem cells in aged mares
• Equine fetal genotyping via aspiration of yolk-sac fluid at 22-28 days of gestation
• Intrafollicular oocyte transfer in the horse
• Conventional vs. Piezo ICSI in the horse: delayed sperm component remodeling and oocyte activation
• Vitrification of germinal-vesicle stage equine oocytes
• Culture of somatic cells isolated from frozen-thawed equine semen using fluorescence-assisted cell sorting
• Accuracy of preimplantation genetic diagnosis in equine in vivo-recovered and in vitro-produced blastocysts
• Cell lineage allocation in equine blastocysts cultured in varying glucose concentrations
• Timing factors affecting blastocyst development in equine somatic cell nuclear transfer
• Regulation of axonemal motility in demembranated equine sperm
Selected Publications
Angel, D., Canesin, H. S., Brom-de-Luna, J. G., Morado, S., Dalvit, G., Gomez, D., Posada, N., Pascottini, O. B., Urrego, R., Hinrichs, K., Velez, I. C.: Embryo development after vitrification of immature and in vitro-matured equine oocytes. Cryobiology 2020.Ripley, A. M., Penedo, M. C. T., Grahn, R. A., Martinez de Andino, E. V., Walbornn, S. R., Serafini, R., Love, C. C., Hinrichs, K.: Equine fetal genotyping via aspiration of yolk-sac fluid at 22–28 days of gestation. Theriogenology 142: 34-40, 2020.
Brom-De-Luna, J. G., Salgado, R. M., Canesin, H. S., Diaw, M., Hinrichs, K.: Equine blastocyst production under different incubation temperatures and different CO
Marzano, G., Mastrorocco, A., Zianni, R., Mangiacotti, M., Chiaravalle, A. E., Lacalandra, G. M., Minervini, F., Cardinali, A., Macciocca, M., Vicenti, R., Fabbri, R., Hinrichs, K., Dell’Aquila, M. E., Martino, N. A.: Altered morphokinetics in equine embryos from oocytes exposed to DEHP during IVM. Molecular Reproduction and Development 86(10): 1388-1404, 2019.
Martino, N. A., Marzano, G., Mastrorocco, A., Lacalandra, G. M., Vincenti, L., Hinrichs, K., Dell'Aquila, M. E.: Use of time-lapse imaging to evaluate morphokinetics of in vitro equine blastocyst development after oocyte holding for two days at 15°C versus room temperature before intracytoplasmic sperm injection. Reproduction, Fertility and Development 31(12): 1862-1873, 2019.
Martinez de Andino, E., Brom-de-Luna, J., Canesin, H., Rader, K., Resende, H., Ripley, A., Love, C., Hinrichs, K.: Intrafollicular oocyte transfer in the horse: effect of autologous vs. allogeneic transfer and time of administration of ovulatory stimulus before transfer. Journal of Assisted Reproduction and Genetics 36(6): 1237-1250, 2019.
Lewis, N., Schnauffer, K., Hinrichs, K., Morganti, M., Troup, S., Argo, C.: Morphokinetics of early equine embryo development in vitro using time-lapse imaging, and use in selecting blastocysts for transfer. Reproduction, Fertility and Development 31(12): 1851-1861, 2019.
Kelley, D. E., Hodo, C. L., Aceino, A., Lawhon, S. D., Hinrichs, K., Brinsko, S. P.: Abortion due to Bacillus pumilus in a mare. Equine Veterinary Education 2019.
Grady, S. T., Watts, A. E., Thompson, J. A., Penedo, M. C. T., Konganti, K., Hinrichs, K.: Effect of intra-ovarian injection of mesenchymal stem cells in aged mares. Journal of Assisted Reproduction and Genetics 36(3): 543-556, 2019.
Grady, S. T., Britton, L., Hinrichs, K., Nixon, A. J., Watts, A. E.: Persistence of fluorescent nanoparticle-labelled bone marrow mesenchymal stem cells in vitro and after intra-articular injection. Journal of Tissue Engineering and Regenerative Medicine 13(2): 191-202, 2019.