Raymond W Sweeney
Professor Emeritus of Medicine, University of Pennsylvania School of Veterinary Medicine
Contact information
University of Pennsylvania
School of Veterinary Medicine
Dept of Clinical Studies
New Bolton Center
382 West Street Road
Kennett Square, PA 19348
School of Veterinary Medicine
Dept of Clinical Studies
New Bolton Center
382 West Street Road
Kennett Square, PA 19348
Office: 610-925-6132
Fax: 610-925-6800
Fax: 610-925-6800
Email:
rsweeney@vet.upenn.edu
rsweeney@vet.upenn.edu
Education:
A.B. (Chemistry)
Dartmouth College, 1978.
V.M.D. (Veterinary Medicine)
University of Pennsylvania School of Veterinary Medicine, 1982.
Permanent linkA.B. (Chemistry)
Dartmouth College, 1978.
V.M.D. (Veterinary Medicine)
University of Pennsylvania School of Veterinary Medicine, 1982.
Description of Research Expertise
Paratuberculosis (Johne's Disease)-Diagnosis
-Immune Response
-Experimental Infection Models
-Vaccination
Pharmacokinetics of antimicrobial drugs
Description of Clinical Expertise
Large Animal Internal MedicineSelected Publications
Beaver, A, Sweeney, R.W., Hovingh, E., Wolfgang, D.R., Gröhn, Y.T., Schukken, Y.H. : Longitudinal relationship between fecal culture, fecal quantitative PCR, and milk ELISA in Mycobacterium avium ssp. paratuberculosis-infected cows from low-prevalence dairy herds. J Dairy Science 100: 7507, 2017.Fecteau M-E, Pitta DW, Vecchiarellis B, Indugu N, Kumar S, Gallagher SC, Fyock TL, Sweeney RW: Dysbiosis of the fecal microbiota in cattle infected with Mycobacterium avium subsp. paratuberculosis. PLoS ONE 11, 2016.
Sweeney RW, Whitlock RH, Bowersock TL, Cleary DL, Meinert TR, Habecker PL, Pruitt GW: Effect of subcutaneous administration of a killed Mycobacterium avium subsp. paratuberculosis vaccine on colonization of tissues following oral exposure to the organism in calves. Am J Vet Res 70: 493-498, 2009.
Sweeney RW, Collins MT, Koets AP, McGuirk SM, Roussel AJ: ACVIM Consensus Statement: Paratuberculosis (Johne’s Disease) in cattle and other susceptible species. Journal of Vet Int Med 26: 1239, 2012.
Fecteau ME, Whitlock RH, Fyock TL, McAdams SC, Boston RC, Sweeney RW: Antimicrobial activity of gallium nitrate against Mycobacterium avium subsp. paratuberculosis in neonatal calves. J Vet Int Med 25: 1152-1155, 2011.
Sweeney RW., Uzonna J., Whitlock RH., Habecker PL., Chilton P., Scott P.: Tissue predilection sites and effect of dose on Mycobacterium avium subs. paratuberculosis organism recovery in a short-term bovine experimental oral infection model. Research in Veterinary Science 80(3): 253-9, Jun 2006.
Uzonna JE., Chilton P., Whitlock RH., Habecker PL., Scott P., Sweeney RW.: Efficacy of commercial and field-strain Mycobacterium paratuberculosis vaccinations with recombinant IL-12 in a bovine experimental infection model. Vaccine 21(23): 3101-9, Jul 4 2003.
Sweeney RW, Whitlock RH, McAdams S: Comparison of three DNA preparation methods for real-time PCR confirmation of Mycobacterium avium subsp. paratuberculosis growth in an automated broth culture system. Journal Veterinary Diagnostic Investigation 18: 587-590, 2006.
Sweeney RW., Jones DE., Habecker P., Scott P.: Interferon-gamma and interleukin 4 gene expression in cows infected with Mycobacterium paratuberculosis. American Journal of Veterinary Research 59(7): 842-7, Jul 1998.
Sweeney RW., Whitlock RH., Rosenberger AE.: Mycobacterium paratuberculosis cultured from milk and supramammary lymph nodes of infected asymptomatic cows. Journal of Clinical Microbiology 30(1): 166-71, Jan 1992.
Sweeney RW., Whitlock RH., Buckley CL., Spencer P., Rosenberger AE., Hutchinson LJ.: Diagnosis of paratuberculosis in dairy cattle, using enzyme-linked immunosorbent assay for detection of antibodies against Mycobacterium paratuberculosis in milk. American Journal of Veterinary Research 55(7): 905-9, Jul 1994.
Johnson AL, McAdams-Gallagher SC, Sweeney RW: Quantitative real-time PCR for detection of neurotoxin genes of Clostridium botulinum types A, B, and C in equine samples. Veterinary Journal 199: 157, 2014.
Sielman ES., Sweeney RW., Whitlock RH., Reams RY.: Hypokalemia syndrome in dairy cows: 10 cases (1992-1996). Journal of the American Veterinary Medical Association 210(2): 240-3, Jan 15 1997.