Julie B. Engiles
Professor of Pathology, School of Veterinary Medicine
Department of Clinical Studies- New Bolton Center
Professor of Pathology, School of Veterinary Medicine
Department of Pathobiology
Contact information
University of Pennsylvania
New Bolton Center
Murphy Laboratory
382 West Street Road
Kennett Square, PA 19348
New Bolton Center
Murphy Laboratory
382 West Street Road
Kennett Square, PA 19348
Office: 610-925-6451
Fax: 610-925-6810
Lab: 610-925-6232
Fax: 610-925-6810
Lab: 610-925-6232
Email:
engiles@vet.upenn.edu
engiles@vet.upenn.edu
Publications
Education:
B.A. (Biophysics, Dean's Scholar Program)
University of Delaware, 1994.
VMD
School of Veterinary Medicine, University of Pennsylvania, 2002.
DACVP (Veterinary Anatomic Pathology )
University of Pennsylvania, 2006.
Permanent linkB.A. (Biophysics, Dean's Scholar Program)
University of Delaware, 1994.
VMD
School of Veterinary Medicine, University of Pennsylvania, 2002.
DACVP (Veterinary Anatomic Pathology )
University of Pennsylvania, 2006.
Description of Research Expertise
Julie Engiles is a Professor of Pathology at the University of Pennsylvania, School of Veterinary Medicine (PennVet). After receiving her VMD from PennVet in 2002 she completed a Surgical Internship (NJ Equine Clinic, 2003), followed by an Anatomic Pathology Residency (PennVet, 2006) with ACVP boards-certification. Dr. Engiles was appointed on faculty at PennVet, New Bolton Center in 2007, where she provides autopsy and biopsy services for the Pennsylvania Animal Diagnostic Laboratory System (PADLS) and teaching hospital. Dr. Engiles also provides research-related services that support clinical and translational large animal models. As a diagnostic pathologist, she employs a multi-disciplinary approach that correlates gross and histologic lesions with clinical and radiologic manifestations to improve diagnostic and prognostic accuracy and expand understanding of disease pathogenesis. Her research expertise includes equine pathology and orthopedic pathology, including equine laminitis.Selected Publications
Peredo AP, Gullbrand SE, Friday CS, Orozco BS, Dehghani B, Jenk AC, Bonnevie ED, Hilliard RL, Zlotnick HM, Dodge GR, Lee D, Engiles JB, Hast MW, Schaer TP, Smith HE, Mauck RL.: Tension-activated nanofiber patches delivering an anti-inflammatory drug improve repair in a goat intervertebral disc herniation model. Sci Transl Med 15: eadf1690, Nov 2023.Engiles JB, Fanzone N, Wulster KB, Schumacher J, Pierdon MK.: Gross, histopathologic, microbiologic, and radiologic characterization of lesions associated with clinical lameness in a cohort of group-housed sows euthanized for lameness. Vet Pathol Aug 2022.
Gilbertie JM, Schaer TP, Engiles JB, Seiler GS, Deddens BL, Schubert AG, Jacob ME, Stefanovski D, Ruthel G, Hickok NJ, Stowe DM, Frink A, Schnabel LV.: A Platelet-Rich Plasma-Derived Biologic Clears Staphylococcus aureus Biofilms While Mitigating Cartilage Degeneration and Joint Inflammation in a Clinically Relevant Large Animal Infectious Arthritis Model. Front Cell Infect Microbiol 12: 895022, May 2022.
Gullbrand Sarah E, Ashinsky Beth G, Bonnevie Edward D, Kim Dong Hwa, Engiles Julie B, Smith Lachlan J, Elliott Dawn M, Schaer Thomas P, Smith Harvey E, Mauck Robert L: Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc. Science translational medicine 10(468), Nov 2018.
Lee NN, Salzer E, Bach FC, Bonilla AF, Cook JL, Gazit Z, Grad S, Ito K, Smith LJ, Vernengo A, Wilke HJ, Engiles JB, Tryfonidou MA.: A comprehensive tool box for large animal studies of intervertebral disc degeneration. JOR Spine 4: e1162, Jun 2021.
Engiles JB, Uzal FA, Navarro MA, Reef VB, Bender SJ.: Phlegmonous gastritis in 2 yearling horses. J Vet Diagn Invest Jan 2022.
Stewart H L, Southwood L L, Indugu N, Vecchiarelli B, Engiles J B, Pitta D: Differences in the equine faecal microbiota between horses presenting to a tertiary referral hospital for colic compared to an elective surgical procedure. Equine veterinary journal Aug 2018.
Sateriale Adam, Šlapeta Jan, Baptista Rodrigo, Engiles Julie B, Gullicksrud Jodi A, Herbert Gillian T, Brooks Carrie F, Kugler Emily M, Kissinger Jessica C, Hunter Christopher A, Striepen Boris: A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective Immunity. Cell host & microbe 26(1): 135-146.e5, 07 2019.
Cassimeris L, Engiles JB, Galantino-Homer H.: Interleukin-17A pathway target genes are upregulated in Equus caballus supporting limb laminitis. PLoS One 15: e0232920, Dec 2020.
Casal Margret L, Engiles Julie B, Zakošek Pipan Maja, Berkowitz Asaf, Porat-Mosenco Yael, Mai Wilfried, Wurzburg Kirsten, Xu Mei-Qi, Allen Robyn, ODonnell Patricia A, Henthorn Paula S, Thompson Keith, Shore Eileen M: Identification of the Identical Human Mutation in in 2 Cats With Fibrodysplasia Ossificans Progressiva. Veterinary pathology 56(4): 614-618, 07 2019.