Angela K Brice
Director of Diagnostics and Quality Assurance, University of Pennsylvania Laboratory Animal Resources (ULAR)
Associate Professor, Laboratory Animal Medicine, University of Pennsylvania
School of Veterinary Medicine
Contact information
University Laboratory Animal Resources
Old Vet Quadrangle, Suite 177E
School of Veterinary Medicine
3800 Spruce Street
Philadelphia, PA 19104-6009
Old Vet Quadrangle, Suite 177E
School of Veterinary Medicine
3800 Spruce Street
Philadelphia, PA 19104-6009
Office: 215.898.4009
Fax: 215.573.9998
Fax: 215.573.9998
Email:
abrice@upenn.edu
abrice@upenn.edu
Publications
Education:
BS
North Carolina Agricultural and Technical State University, 1998.
DVM
Tuskegee University School of Veterinary Medicine, 2002.
PhD
Johns Hopkins University, 2009.
Permanent linkBS
North Carolina Agricultural and Technical State University, 1998.
DVM
Tuskegee University School of Veterinary Medicine, 2002.
PhD
Johns Hopkins University, 2009.
Description of Research Expertise
• Anti-vascular Endothelial Growth Factor Receptor-2 Antibody Accelerates Renal Disease Progression in the NZB/W F1 Murine SystemicLupus Erythematosus Model
• Coordinated Regulation of SIV replication and
Immune Responses in the CNS
• Systemic Activation of K-ras Rapidly Induces Gastric Hyperplasia and Metaplasia
• Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks.
Selected Publications
Brent, J. M., Tian, Z., Yao, L., Huang, J., Markova, D. Z., Shofer, F. S., Brice, A. K., Qin, L., Scanzello, C. R., Vitale, F., Chen, D., Zhang, Y.: Functional deficits in mice expressing human interleukin 8. Comp Med 70(3): 205-215, 2020.Wilson, J. M., Wallace, C. K., Brice, A. K., Makaron, L.: Mineralized trichobezoars in a Rhesus Macaque (Macaca Mulatta). J Med Primatol 49(3): 158-161, 2020.
Karmacharya, M. B., Sultan, L. R., Kirkham, B. M., Brice, A. K., Wood, A. K. W., Sehgal, C. M.: Photoacoustic imaging for assessing tissue oxygenation changes in rat hepatic fibrosis. Diagnostics (Basel) 10(9), 2020.
Ortiz, A., Gui, J., Zahedi, F., Yu, P., Cho, C., Bhattacharya, S., Carbone, C. J., Yu, Q., Katlinski, K. V., Katlinskaya, Y. V., Handa, S., Haas, V., Volk, S. W., Brice, A. K., Wals, K., Matheson, N. J., Antrobus, R., Ludwig, S., Whiteside, T. L., Sander, C., Tarhini, A. A., Kirkwood, J. M., Lehner, P. J., Guo, W., Rui, H., Minn, A. J., Koumenis, C., Diehl, J. A., Fuchs, S. Y.: An interferon-driven oxysterol-based defense against tumor-derived extracellular vesicles. Cancer Cell 35(1): 33-45 e6, 2019.
D'Souza, J. C., Sultan, L. R., Hunt, S. J., Schultz, S. M., Brice, A. K., Wood, A. K. W., Sehgal, C. M.: B-mode ultrasound for the assessment of hepatic fibrosis: a quantitative multiparametric analysis for a radiomics approach. Sci Rep 9(1): 8708, 2019.
D'Souza, J. C., Sultan, L. R., Hunt, S. J., Gade, T. P., Karmacharya, M. B., Schultz, S. M., Brice, A. K., Wood, A. K. W., Sehgal, C. M.: Microbubble-enhanced ultrasound for the antivascular treatment and monitoring of hepatocellular carcinoma. Nanotheranostics 3(4): 331-341, 2019.
Bright, L. A., Gardiner, K. L., Veeder, C. L., Brice, A. K.: Hepatic hemangiosarcoma in a Cynomolgus Macaque (Macaca Fascicularis). Comp Med 69(3): 240-248, 2019.
Misic, A. M., Miedel, E. L., Brice, A. K., Cole, S., Zhang, G. F., Dyer, C. D., Secreto, A., Smith, A. L., Danet-Desnoyers, G., Beiting, D. P.: Culture-independent profiling of the fecal microbiome to identify microbial species associated with a diarrheal outbreak in immunocompromised mice. Comp Med 68(4): 261-268, 2018.
de Souza Dyer, C., Brice, A. K., Marx, J. O.: Intraperitoneal administration of ethanol as a means of euthanasia for neonatal mice (Mus Musculus). J Am Assoc Lab Anim Sci 56(3): 299-306, 2017.
Johnston, J. M., Dyer, C. D., Madison-Antenucci, S., Mergen, K. A., Veeder, C. L., Brice, A. K.: Neurocysticercosis in a Rhesus Macaque (Macaca mulatta). Comp Med 66(6): 499-502, 2016.
Mice and Men.