Selected Publications

Takahashi K, Kwok JC, Sato Y, Aguirre GD, Miyadera K.: Extended functional rescue following AAV gene therapy in a canine model of LRIT3-congenital stationary night blindness. Vision Research 209: 108260, May 2023.

Ripolles-Garcia A, Murgiano L, Ziolkowska N, Marinho FP, Roszak K, Iffrig S, Aguirre GD, Miyadera K.: Natural disease history of a canine model of oligogenic RPGRIP1-cone-rod dystrophy establishes variable effects of previously and newly mapped modifier loci. Human Molecular Genetics Page: ddad046, Mar 2023.

Gray AP, Sato Y, Miyadera K, Aguirre GD.: Novel insights into chorioretinal and juxtapapillary colobomas by optical coherence tomography. Veterinary Ophthalmology 25(Suppl 1): 136-143, May 2022.

Miyadera K, Santana E, Roszak K, Iffrig S, Visel M, Iwabe S, Boyd RF, Bartoe JT, Sato Y, Gray A, Ripolles-Garcia A, Dufour VL, Byrne LC, Flannery JG, Beltran WA, Aguirre GD.: Targeting ON-bipolar cells by AAV gene therapy stably reverses LRIT3-congenital stationary night blindness. Proc Natl Acad Sci U S A 119: e2117038119, Mar 2022.

Sato Y, Gray A, Takahashi K, Dufour V, Lutty G, Miyadera K, Aguirre G.: Monocular retinopathy of prematurity-like retinal vasculopathy in a dog. Veterinary Ophthalmology 25(1): 78-84, Jan 2022.

Miyadera K, Conatser L, Llanga TA, Carlin K, O'Donnell P, Bagel J, Song L, Kurtzberg J, Samulski RJ, Gilger B, Hirsch ML.: Intrastromal gene therapy prevents and reverses advanced corneal clouding in a canine model of mucopolysaccharidosis I. Molecular Therapy 28(6): 1455-1463, Jun 2020.

Das RG, Becker D, Jagannathan V, Goldstein O, Santana E, Carlin K, Sudharsan R, Leeb T, Nishizawa Y, Kondo M, Aguirre GD, Miyadera K.: Genome-wide association study and whole-genome sequencing identify a deletion in LRIT3 associated with canine congenital stationary night blindness. Scientific Reports 9(1): 14166, Oct 2019.

Das Rueben G, Marinho Felipe Pompeo, Iwabe Simone, Santana Evelyn, McDaid Kendra Sierra, Aguirre Gustavo D, Miyadera Keiko: Variabilities in retinal function and structure in a canine model of cone-rod dystrophy associated with RPGRIP1 support multigenic etiology. Scientific Reports 7(1): 12823, Oct 2017.

Forman OP, Hitti RJ, Boursnell M, Miyadera K, Sargan D, Mellersh C: Canine genome assembly correction facilitates identification of a MAP9 deletion as a potential age of onset modifier for RPGRIP1-associated canine retinal degeneration. Mammalian Genome 27(5-6): 237-45, Jun 2016.

Tanaka N, Dutrow EV, Miyadera K, Delemotte L, MacDermaid CM, Reinstein SL, Crumley WR, Dixon CJ, Casal ML, Klein ML, Aguirre GD, Tanaka JC, Guziewicz KE.: Canine CNGA3 gene mutations provide novel insights into human achromatopsia-associated channelopathies and treatment. PLoS One 10(9): e0138943, 2015.