Joy E Tomlinson
Assistant Professor of Large Animal Medicine (CE), University of Pennsylvania School of Veterinary Medicine
Contact information
University of Pennsylvania, School of Veterinary Medicine
New Bolton Center
382 West Street Road
Kennett Square, PA 19348-1692
New Bolton Center
382 West Street Road
Kennett Square, PA 19348-1692
Office: 610-925-6439
Email:
joytom@vet.upenn.edu
joytom@vet.upenn.edu
Publications
Education:
BS (Engineering)
Cornell University, 2006.
DVM (Veterinary Medicine)
Cornell University College of Veterinary Medicine, 2010.
PhD (Immunology and Infectious Disease)
Cornell University College of Veterinary Medicine, 2022.
Permanent linkBS (Engineering)
Cornell University, 2006.
DVM (Veterinary Medicine)
Cornell University College of Veterinary Medicine, 2010.
PhD (Immunology and Infectious Disease)
Cornell University College of Veterinary Medicine, 2022.
Description of Clinical Expertise
Large Animal Internal MedicineHepatology/Liver disease
Headshaking syndrome
Primary hyperparathyroidism
Equine multinodular pulmonary fibrosis
Description of Research Expertise
Viral pathogenesis in horses. Specifically, my research program is focusing on recently discovered liver viruses in equids including Equine parvovirus-hepatitis, Equine hepacivirus, and Equid hepadnavirus. We are characterizing the routes of transmission, disease associations, and pathogenesis of each virus with a goal to develop treatment and prevention approaches.Selected Publications
Tomlinson, J. E., Jager, M., Struzyna, A., Laverack, M., Fortier, L. A., Dubovi, E., Foil, L. D., Burbelo, P. D., Divers, T. J., Van de Walle, G. R.: Tropism, pathology, and transmission of equine parvovirus-hepatitis. Emerging Microbes and Infections 9(1): 651-663, 2020.Tomlinson, J. E., Wolfisberg, R., Fahnoe, U., Patel, R. S., Trivedi, S., Kumar, A., Sharma, H., Nielsen, L., McDonough, S. P., Bukh, J., Tennant, B. C., Kapoor, A., Rosenberg, B. R., Rice, C. M., Divers, T. J., Van de Walle, G. R., Scheel, T. K. H.: Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection. Hepatology 74(3): 1148-1163, 2021.
Cavalleri, J. V., Korbacska-Kutasi, O., Leblond, A., Paillot, R., Pusterla, N., Steinmann, E., Tomlinson, J.: European College of Equine Internal Medicine consensus statement on equine flaviviridae infections in Europe. Journal of Veterinary Internal Medicine 36(6): 1858-1871, 2022.
Jager, M. C., Choi, E., Tomlinson, J. E., Van de Walle, G.: Naturally acquired equine parvovirus-hepatitis is associated with a wide range of hepatic lesions in horses. Veterinary Pathology Page: 3009858231214024, 2023.
Tomlinson, J. E., Van de Walle, G. R.: Nasal transmission of equine parvovirus hepatitis. Journal of Veterinary Internal Medicine 36(6): 2238-2244, 2022.
Jager, M. C., Tomlinson, J. E., Henry, C. E., Fahey, M. J., Van de Walle, G. R.: Prevalence and pathology of equine parvovirus-hepatitis in racehorses from New York racetracks. Virology Journal 19(1): 175, 2022.
Tomlinson, J. E., Tennant, B. C., Struzyna, A., Mrad, D., Browne, N., Whelchel, D., Johnson, P. J., Jamieson, C., Lohr, C. V., Bildfell, R., McKenzie, E. C., Laverack, M., Renshaw, R. W., Dubovi, E., Kapoor, A., Meirs, R. S., Belgrave, R., Engiles, J., Van de Walle, G. R., Divers, T. J.: Viral testing of 10 cases of Theiler''s disease and 37 in-contact horses in the absence of equine biologic product administration: A prospective study (2014-2018). Journal of Veterinary Internal Medicine 33(1): 258-265, 2019.
Divers, T. J., Tomlinson, J. E., Tennant, B. C.: The history of Theiler''s disease and the search for its aetiology. Veterinary Journal 287: 105878, 2022.
Tomlinson, J. E., Kapoor, A., Kumar, A., Tennant, B. C., Laverack, M. A., Beard, L., Delph, K., Davis, E., Schott Ii, H., Lascola, K., Holbrook, T. C., Johnson, P., Taylor, S. D., McKenzie, E., Carter-Arnold, J., Setlakwe, E., Fultz, L., Brakenhoff, J., Ruby, R., Trivedi, S., Van de Walle, G. R., Renshaw, R. W., Dubovi, E. J., Divers, T. J.: Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014-2018). Journal of Veterinary Internal Medicine 33(1): 251-257, 2019.
Jager, M. C., Tomlinson, J. E., Lopez-Astacio, R. A., Parrish, C. R., Van de Walle, G. R.: Small but mighty: old and new parvoviruses of veterinary significance. Virology Journal 18(1): 210, 2021.
Delvescovo, B., Tomlinson, J., DeNotta, S., Hodge, E., Bookbinder, L., Mohammed, H. O., Divers, T. J.: Bile acids, direct bilirubin and gamma-glutamyltransferase as prognostic indicators for horses with liver disease in the eastern United States: 82 cases (1997-2019). Journal of Equine Veterinary Science. W.B. Saunders, 105, 2021.
Mittel L, Norton P, Tomlinson JE, Divers TJ: AAEP Infectious Disease Guidelines: Equine Parvovirus-Hepatitis Virus (EqPV-H). American Association of Equine Practitioners white paper online, 2021.
Patel, R. S., Tomlinson, J. E., Divers, T. J., Van de Walle, G. R., Rosenberg, B. R.: Single-cell resolution landscape of equine peripheral blood mononuclear cells reveals diverse cell types including T-bet(+) B cells. BMC Biology 19(1): 13, 2021.
Gorenberg, E. B., Johnson, A. L., Magdesian, K. G., Bertin, F. R., Costa, L. R. R., Theelen, M. J. P., Durward-Akhurst, S. A., Cruz Villagran, C., Carslake, H., Frank, N., Tomlinson, J. E.: Diagnosis and treatment of confirmed and suspected primary hyperparathyroidism in equids: 17 cases (1999-2016). Equine Veterinary Journal 52(1): 83-90, 2020.
Tomlinson, J. E., Wolfisberg, R., Fahnoe, U., Sharma, H., Renshaw, R. W., Nielsen, L., Nishiuchi, E., Holm, C., Dubovi, E., Rosenberg, B. R., Tennant, B. C., Bukh, J., Kapoor, A., Divers, T. J., Rice, C. M., Van de Walle, G. R., Scheel, T. K. H.: Equine pegiviruses cause persistent infection of bone marrow and are not associated with hepatitis. PLoS Pathogens 16(7): e1008677, 2020.
Fenn, M. S., Bortsie-Aryee, A. D., Perkins, G. A., Mann, S., Tomlinson, J. E., Wood, E. M., Mix, S. E., Stokol, T.: Agreement of stall-side and laboratory major crossmatch tests with the reference standard method in horses. Journal of Veterinary Internal Medicine 34(2): 941-948, 2020.
Vengust, M., Jager, M. C., Zalig, V., Cociancich, V., Laverack, M., Renshaw, R. W., Dubovi, E., Tomlinson, J. E., Van de Walle, G. R., Divers, T. J.: First report of equine parvovirus-hepatitis-associated Theiler''s disease in Europe. Equine Veterinary Journal 52(6): 841-847, 2020.
Radcliffe, R. M., Bookbinder, L. C., Liu, S. Y., Tomlinson, J. E., Cook, V. L., Hurcombe, S. D. A., Divers, T. J.: Collection and administration of blood products in horses: Transfusion indications, materials, methods, complications, donor selection, and blood testing. Journal of Veterinary Emergency and Critical Care (San Antonio, Tex.: 2001) 32(S1): 108-122, 2022.
Tomlinson, J. E., Wagner, B., Felippe, M. J. B., Van de Walle, G. R.: Multispectral fluorescence-activated cell sorting of B and T cell subpopulations from equine peripheral blood. Veterinary Immunology and Immunopathology 199: 22-31, 2018.
Gorenberg EB, Johnson AL, Magdesian KG, Bertin FR, Costa LRR, Theelen MJP, Durward-Arkhurst S, Villagran CC, Carslake H, Frank N, Tomlinson JE. : Medical and surgical treatment of primary hyperparathyroidism in 17 equids (1999-2016). J Vet Intern Med 32(5): 2181-2182, 2018.