Selected Publications

Aparajeeta Majumder, Soomin Jeong, Marco Zamora, Nicolas Marzolini, Yufei Wang, Jia Nong, Taylor Brysgel, Priyal Patel, Michael Zaleski, Jichuan Wu, Collin Stabler, Liam Chase, Zhicheng Wang, Edward Morrisey, Vladimir Muzykantov, Laura Ferguson, Jacob Brenner, Oscar Contreras, Jacob Myerson: Nanoparticle albumin-bound paclitaxel targets pulmonary neutrophils. bioRxiv September 2026.

Stephanie Monson, Sahil Kulkarni, Jacob Myerson, Jacob Brenner, Ravi Radhakrishnan: Percolation-inspired criticality in complement activation: universal scaling and transport-limited complement surface amplification. bioRxiv August 2026.

Jacob W. Myerson and Drew Weissman: Rethink the cargo, rethink the carrier: New transfer RNA medicines require redesigned lipid nanoparticles for delivery. Science 393(6814): 862, August 2026.

Po-Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos-Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom: Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis. Advanced Science June 2026.

Nicolas Marzolini, Taylor V Brysgel, Ryan J Rahman, Eno‐Obong Essien, Saw Y Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N Patel, Sachchidanand Tiwari, Carolann L Espy, Fengyi Dong, Sabrina A Santos‐De León, Anit Shah, Vladimir V Shuvaev, Elizabeth D Hood, Liam S Chase, Drew Weissman, Jeremy B Katzen, David B Frank, Mariko L Bennett, Oscar A Marcos‐Contreras, Jacob W Myerson, Vladimir R Muzykantov, Sahily Reyes‐Esteves, Jacob S Brenne: Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity. Advanced Science 13(14): e15480, March 2026.

Taylor V Brysgel, Elizabeth D Hood, Aleksa Milosavljevic, Nicolas Marzolini, Marco E Zamora, Jichuan Wu, Vladimir V Shuvaev, Tea Shuvaeva, Michael Kegel, Jenna Muscat-Rivera, Drew Weissman, Jilian R Melamed, Jacob W Myerson, Jacob S Brenner, Vladimir R Muzykantov, Jia Nong: Decoupling Physisorption from Chemisorption in Clickable Lipid Nanoparticles. ACS Nanoscience Au February 2026.

Sahily Reyes-Esteves, Aparajeeta Majumder, Nicolas Marzolini, Marco E Zamora, Soomin Jeong, Yufei Wang, Manthan N Patel, Carolann Espy, Tyler Ellis Papp, Awurama Akyianu, Jia Nong, Lawson Messe, Serena Omo-Lamai, Hamideh Parhiz, Jacob W Myerson, Oscar A Marcos-Contreras, Jacob S Brenner: Targeted lipid nanoparticles containing IL-10 mRNA improve outcomes in experimental intracerebral hemorrhage. Journal of Neuroinflammation 22(1), October 2025.

Serena Omo-Lamai, Yufei Wang, Manthan N Patel, Aleksa Milosavljevic, Daniel Zuschlag, Subhajit Poddar, Jichuan Wu, Liuqian Wang, Fengyi Dong, Carolann Espy, Aparajeeta Majumder, Eno-Obong Essien, Mengwen Shen, Breana Channer, Tyler E Papp, Michael Tobin, Rhea Maheshwari, Sumin Jeong, Sofia Patel, Anit Shah, Shruthi Murali, Liam S Chase, Marco E Zamora, Mariah L Arral, Oscar A Marcos-Contreras, Jacob W Myerson, Christopher A Hunter, Dennis Discher, Peter J Gaskill, Andrew Tsourkas, Vladimir R Muzykantov, Igor Brodsky, Sunny Shin, Kathryn A Whitehead, Hamideh Parhiz, Jeremy Katzen, Jonathan J Miner, Dirk Trauner, Jacob S Brenner: Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape. Nature nanotechnology 20(9), September 2025.

Vladimir V Shuvaev, Ying K Tam, Benjamin W Lee, Jacob W Myerson, Alan Herbst, Raisa Yu Kiseleva, Patrick M Glassman, Hamideh Parhiz, Mohamad-Gabriel Alameh, Norbert Pardi, Hiromi Muramatsu, Tea I Shuvaeva, Evguenia Arguiri, Oscar A Marcos-Contreras, Elizabeth D Hood, Taylor V Brysgel, Jia Nong, Tyler E Papp, Deborah M Eaton, Rachel Riley, Rohan Palanki, Kiran Musunuru, Jacob S Brenner, Michael J Mitchell, Victor A Ferrari, Barbara L Mui, Sean C Semple, Sherry A Weppler, Pavan Atluri, Kenneth B Margulies, Drew Weissman, Vladimir R Muzykantov: Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo. Proceedings of the National Academy of Sciences 122(29), July 2025.

Zhicheng Wang, Sahil Kulkarni, Jia Nong, Marco Zamora, Alireza Ebrahimimojarad, Elizabeth Hood, Tea Shuvaeva, Michael Zaleski, Damodar Gullipalli, Emily Wolfe, Carolann Espy, Evguenia Arguiri, Jichuan Wu, Yufei Wang, Oscar A Marcos-Contreras, Wenchao Song, Vladimir R Muzykantov, Jinglin Fu, Ravi Radhakrishnan, Jacob W Myerson, Jacob S Brenner: A percolation phase transition controls complement protein coating of surfaces. Cell 188(15), July 2025.