Selected Publications

Po-Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos-Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom: Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis. Advanced Science June 2026.

Nicolas Marzolini, Taylor V Brysgel, Ryan J Rahman, Eno‐Obong Essien, Saw Y Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N Patel, Sachchidanand Tiwari, Carolann L Espy, Fengyi Dong, Sabrina A Santos‐De León, Anit Shah, Vladimir V Shuvaev, Elizabeth D Hood, Liam S Chase, Drew Weissman, Jeremy B Katzen, David B Frank, Mariko L Bennett, Oscar A Marcos‐Contreras, Jacob W Myerson, Vladimir R Muzykantov, Sahily Reyes‐Esteves, Jacob S Brenne: Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity. Advanced Science 13(14): e15480, March 2026.

Taylor V Brysgel, Elizabeth D Hood, Aleksa Milosavljevic, Nicolas Marzolini, Marco E Zamora, Jichuan Wu, Vladimir V Shuvaev, Tea Shuvaeva, Michael Kegel, Jenna Muscat-Rivera, Drew Weissman, Jilian R Melamed, Jacob W Myerson, Jacob S Brenner, Vladimir R Muzykantov, Jia Nong: Decoupling Physisorption from Chemisorption in Clickable Lipid Nanoparticles. ACS Nanoscience Au February 2026.

Sahily Reyes-Esteves, Aparajeeta Majumder, Nicolas Marzolini, Marco E Zamora, Soomin Jeong, Yufei Wang, Manthan N Patel, Carolann Espy, Tyler Ellis Papp, Awurama Akyianu, Jia Nong, Lawson Messe, Serena Omo-Lamai, Hamideh Parhiz, Jacob W Myerson, Oscar A Marcos-Contreras, Jacob S Brenner: Targeted lipid nanoparticles containing IL-10 mRNA improve outcomes in experimental intracerebral hemorrhage. Journal of Neuroinflammation 22(1), October 2025.

Serena Omo-Lamai, Yufei Wang, Manthan N Patel, Aleksa Milosavljevic, Daniel Zuschlag, Subhajit Poddar, Jichuan Wu, Liuqian Wang, Fengyi Dong, Carolann Espy, Aparajeeta Majumder, Eno-Obong Essien, Mengwen Shen, Breana Channer, Tyler E Papp, Michael Tobin, Rhea Maheshwari, Sumin Jeong, Sofia Patel, Anit Shah, Shruthi Murali, Liam S Chase, Marco E Zamora, Mariah L Arral, Oscar A Marcos-Contreras, Jacob W Myerson, Christopher A Hunter, Dennis Discher, Peter J Gaskill, Andrew Tsourkas, Vladimir R Muzykantov, Igor Brodsky, Sunny Shin, Kathryn A Whitehead, Hamideh Parhiz, Jeremy Katzen, Jonathan J Miner, Dirk Trauner, Jacob S Brenner: Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape. Nature nanotechnology 20(9), September 2025.

Zhicheng Wang, Sahil Kulkarni, Jia Nong, Marco Zamora, Alireza Ebrahimimojarad, Elizabeth Hood, Tea Shuvaeva, Michael Zaleski, Damodar Gullipalli, Emily Wolfe, Carolann Espy, Evguenia Arguiri, Jichuan Wu, Yufei Wang, Oscar A Marcos-Contreras, Wenchao Song, Vladimir R Muzykantov, Jinglin Fu, Ravi Radhakrishnan, Jacob W Myerson, Jacob S Brenner: A percolation phase transition controls complement protein coating of surfaces. Cell 188(15), July 2025.

Vladimir V Shuvaev, Ying K Tam, Benjamin W Lee, Jacob W Myerson, Alan Herbst, Raisa Yu Kiseleva, Patrick M Glassman, Hamideh Parhiz, Mohamad-Gabriel Alameh, Norbert Pardi, Hiromi Muramatsu, Tea I Shuvaeva, Evguenia Arguiri, Oscar A Marcos-Contreras, Elizabeth D Hood, Taylor V Brysgel, Jia Nong, Tyler E Papp, Deborah M Eaton, Rachel Riley, Rohan Palanki, Kiran Musunuru, Jacob S Brenner, Michael J Mitchell, Victor A Ferrari, Barbara L Mui, Sean C Semple, Sherry A Weppler, Pavan Atluri, Kenneth B Margulies, Drew Weissman, Vladimir R Muzykantov: Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo. Proceedings of the National Academy of Sciences 122(29), July 2025.

Michael H Zaleski, Liam S Chase, Elizabeth D Hood, Zhicheng Wang, Jia Nong, Carolann L Espy, Marco E Zamora, Jichuan Wu, Lianne J Morrell, Vladimir R Muzykantov, Jacob W Myerson, Jacob S Brenner: Conjugation chemistry markedly impacts toxicity and biodistribution of targeted nanoparticles, mediated by complement activation. Advanced Materials 37(5), February 2025.

Alina D Peshkova, Taylor V Brysgel, Parth Mody, Jia Nong, Zhicheng Wang, Jacob W Myerson, Rustem I Litvinov, John W Weisel, Jacob S Brenner, Patrick M Glassman, Oscar A Marcos-Contreras, Vladimir R Muzykantov: Biomechanical and functional features of the carrier erythrocytes prolonging circulation time of biotherapeutic targeted to glycophorin A. Bioconjugate Chemistry 36(2), January 2025.

Michael H Zaleski, Serena Omo-Lamai, Jia Nong, Liam S Chase, Jacob W Myerson, Patrick M Glassman, Florence Lee, Sahily Reyes-Esteves, Zhicheng Wang, Manthan N Patel, Alina D Peshkova, Hiroaki Komatsu, Paul H Axelsen, Vladimir R Muzykantov, Oscar A Marcos-Contreras, Jacob S Brenner: Nanocarriers' repartitioning of drugs between blood subcompartments as a mechanism of improving pharmacokinetics, safety, and efficacy. Journal of Controlled Release 374, October 2024.