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Dirk Trauner, PhD
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George A. Weiss University Professor
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Department: Systems Pharmacology and Translational Therapeutics
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Contact information
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231 South 34th Street
Philadelphia, PA 10003
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Email:
dtrauner@upenn.edu
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dtrauner@upenn.edu
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Graduate Group Affiliations
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Publications
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Education:
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36 University of Vienna, Austria, 1997.
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Permanent link21 8 PhD c
36 University of Vienna, Austria, 1997.
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eb Mukhopadyhay, T.; Morstein, J.; Trauner, D.: Photopharmacological Control Hof Cell Signaling with Photoswitchable Lipids. Curr. Opin. Pharmacol. 63: 102202, 2022.
c5 Hetzler, B.E.; Trauner, D.; Lawrence, A.L.: Natural Product Anticipation Through Synthesis. Nat. Rev. Chem 6: 170-181, 2022.
11c Morstein, J.; Romano, G.; Hetzler, B.E.; Plante, A.; Haake, C.; Levitz. J.*, Trauner, D.*: Photoswitchable Serotonins for Optical Control of the 5-HT2A Receptor. Angew. Chem. Int. Ed. 61, 2022 Notes: e202117094.
122 Pritzl, S. D.; Konrad, D. B.; Ober, M. F.; Richter, A. F.; Frank, J. A.; Nickel, B.; Trauner, D.; Lohmüller, T.: Optical Membrane Control with Red Light Enabled by Red-Shifted Photolipids. Langmuir 38: 385-393, 2022.
120 Doroudgar, M.; Morstein, J.; Becker-Baldus, J.; Trauner, D.; Glaubitz. C.: How Photoswitchable Lipids Affect the Order and Dynamics of Lipid Bilayers and Embedded Proteins J. Am. Chem. Soc. 143: 9515–9528, 2021.
17d Matsuura, B. S.; Huss, S.; Zheng, Z.; Yuan, S.; Wang, T.; Chen, B.; Badding, J. V.; Trauner, D.; Elacqua, E.; van Duin, A. C. T.; Crespi, V. H.; Schmidt-Rohr, K.: Perfect and Defective 13C-Furan-Derived Nanothreads from Modest-Pressure Synthesis Analyzed by 13C NMR J. Am. Chem. Soc. 143: 9529–9542, 2021.
16a Morstein, J.; Kol, M.; Novak, A. J. E.; Feng, S.; Khayyo, S.; Hinnah,K.; Li-Purcell, N.; Pan, G.; Williams, B. M.; Riezman, H.; Atilla-Gokcumen, G. E.; Holthuis, J. C. M.; Trauner, D.: Short Photoswitchable Ceramides Enable Optical Control of Apoptosis. ACS Chem. Biol. 16: 452¬456, 2021.
f5 Konrad, D.; Ruehmann, P.; Ando, H.; Hetzler, B.; Matsuura, B.*, Trauner, D.*: An Efficient Synthesis of Tetrodotoxin. ChemRxiv 2021 Notes: DOI 10.33774/chemrxiv-2021-xkftp.
117 Donthamsetti, P.; Konrad, D. B.; Hetzler, B.; Fu, Z.; Trauner, D.;* Isacoff, E. Y.*: Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor J. Am. Chem. Soc. 143: 8951–8956, 2021.
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Selected Publications
12e Impastato, A. C.; Shemet, A.; Vepřek, N. A.; Saper, G.; Rao, L.; Hess, H.; Gennerich, A.; Trauner, D.: Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor" Impastato. Angew. Chem. Int. Ed. 61, 2022 Notes: e202115846.eb Mukhopadyhay, T.; Morstein, J.; Trauner, D.: Photopharmacological Control Hof Cell Signaling with Photoswitchable Lipids. Curr. Opin. Pharmacol. 63: 102202, 2022.
c5 Hetzler, B.E.; Trauner, D.; Lawrence, A.L.: Natural Product Anticipation Through Synthesis. Nat. Rev. Chem 6: 170-181, 2022.
11c Morstein, J.; Romano, G.; Hetzler, B.E.; Plante, A.; Haake, C.; Levitz. J.*, Trauner, D.*: Photoswitchable Serotonins for Optical Control of the 5-HT2A Receptor. Angew. Chem. Int. Ed. 61, 2022 Notes: e202117094.
122 Pritzl, S. D.; Konrad, D. B.; Ober, M. F.; Richter, A. F.; Frank, J. A.; Nickel, B.; Trauner, D.; Lohmüller, T.: Optical Membrane Control with Red Light Enabled by Red-Shifted Photolipids. Langmuir 38: 385-393, 2022.
120 Doroudgar, M.; Morstein, J.; Becker-Baldus, J.; Trauner, D.; Glaubitz. C.: How Photoswitchable Lipids Affect the Order and Dynamics of Lipid Bilayers and Embedded Proteins J. Am. Chem. Soc. 143: 9515–9528, 2021.
17d Matsuura, B. S.; Huss, S.; Zheng, Z.; Yuan, S.; Wang, T.; Chen, B.; Badding, J. V.; Trauner, D.; Elacqua, E.; van Duin, A. C. T.; Crespi, V. H.; Schmidt-Rohr, K.: Perfect and Defective 13C-Furan-Derived Nanothreads from Modest-Pressure Synthesis Analyzed by 13C NMR J. Am. Chem. Soc. 143: 9529–9542, 2021.
16a Morstein, J.; Kol, M.; Novak, A. J. E.; Feng, S.; Khayyo, S.; Hinnah,K.; Li-Purcell, N.; Pan, G.; Williams, B. M.; Riezman, H.; Atilla-Gokcumen, G. E.; Holthuis, J. C. M.; Trauner, D.: Short Photoswitchable Ceramides Enable Optical Control of Apoptosis. ACS Chem. Biol. 16: 452¬456, 2021.
f5 Konrad, D.; Ruehmann, P.; Ando, H.; Hetzler, B.; Matsuura, B.*, Trauner, D.*: An Efficient Synthesis of Tetrodotoxin. ChemRxiv 2021 Notes: DOI 10.33774/chemrxiv-2021-xkftp.
117 Donthamsetti, P.; Konrad, D. B.; Hetzler, B.; Fu, Z.; Trauner, D.;* Isacoff, E. Y.*: Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor J. Am. Chem. Soc. 143: 8951–8956, 2021.
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