Clyde E. Markowitz, M.D.
Associate Professor of Neurology at the Hospital of the University of Pennsylvania
Department: Neurology
Contact information
Hospital of the University of Pennsylvania
3 West Gates Building
3400 Spruce Street
Philadelphia, PA 19104
3 West Gates Building
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-4521
Fax: 215-349-5579
Fax: 215-349-5579
Email:
cmarkowi@mail.med.upenn.edu
cmarkowi@mail.med.upenn.edu
Education
B.S. (Business Administration)
State University of New York at Buffalo, 1982.
(Post-baccalaureate pre-med program)
Columbia University, 1986.
M.D. (Medicine)
Columbia Univ. College of Physicians & Surgeons, 1990.
B.S. (Business Administration)
State University of New York at Buffalo, 1982.
(Post-baccalaureate pre-med program)
Columbia University, 1986.
M.D. (Medicine)
Columbia Univ. College of Physicians & Surgeons, 1990.
Post-Graduate Training
Internal Medicine, Columbia-Presbyterian Medical Center New York, N.Y., 1990-1991.
Resident in Neurology, Neurological Institute-Columbia-Presbyterian Medical Center New York, N.Y. , 1991-1994.
Neuroimmunology/MS-Research/Clinical Postdoc. Fellowship, Neurological Institute- Columbia-Presbyterian Medical Center New York, N.Y., 1994-1998.
Internal Medicine, Columbia-Presbyterian Medical Center New York, N.Y., 1990-1991.
Resident in Neurology, Neurological Institute-Columbia-Presbyterian Medical Center New York, N.Y. , 1991-1994.
Neuroimmunology/MS-Research/Clinical Postdoc. Fellowship, Neurological Institute- Columbia-Presbyterian Medical Center New York, N.Y., 1994-1998.
Certifications
National Board of Medical Examiners, 1991.
American Board of Psychiatry and Neurology, 1995.
American Board of Psychiatry and Neurology- Recertification, 2005.
Permanent linkNational Board of Medical Examiners, 1991.
American Board of Psychiatry and Neurology, 1995.
American Board of Psychiatry and Neurology- Recertification, 2005.
Selected Publications
Miller TM, Cudkowicz ME, Shaw PJ, Genge A, Sobue G, Bucelli RC, Chiò A, Van Damme P, Ludolph AC, Glass JD, Andrews JA, Babu S, Benatar M, McDermott CJ, Salachas F, Bruneteau G, Al-Chalabi A, Amorin M, Nestorov I, Graham D, Lin L, Sun P, McNeill M, Malek S, Inra J, Garafalo S, Fradette S; VALOR and OLE Working Group.: Long-Term Tofersen in SOD1 Amyotrophic Lateral Sclerosis. JAMA Neurol 83: 115-125, Feb 2026.Cooper EC, Schindler MK, Bar-Or A, Brandstadter RB, Calkins ME, Gur R, Jacobs DA, Markowitz C, Moore T, Naydovich LR, Perrone CM, Ruparel K, Spangler BC, Troyan S, Shinohara RT, Satterthwaite TD, Baller EB.: Investigating mood and cognition in people with multiple sclerosis: a prospective cross-sectional study protocol. BMJ Open 15: e094733, May 2025.
Naydovich LR, Orthmann-Murphy JL, Markowitz CE.: Beyond relapses: How BTK inhibitors are shaping the future of progressive MS treatment. Neurotherapeutics 22 (4), July 2025.
Baller EB, Sweeney EM, Cieslak M, Robert-Fitzgerald T, Covitz SC, Martin ML, Schindler MK, Bar-Or A, Elahi A, Larsen BS, Manning AR, Markowitz CE, Perrone CM, Rautman V, Seitz MM, Detre JA, Fox MD, Shinohara RT, Satterthwaite TD.: Mapping the Relationship of White Matter Lesions to Depression in Multiple Sclerosis. Biol Psychiatry 95: 1072-1080, Jun 2024.
Martin ML, Robert-Fitzgerald T, Schindler MK, Perrone C, Schultz G, Lynch S, Mirkovic N, Thomas S, Elahi A, Reid D, Moore TM, Baller EB, Satterthwaite TD, Cieslak M, Covitz S, Adebimpe A, Manning A, Markowitz CE, Detre JA, Bar-Or A, Kakara M, Shinohara RT.: Impact of insurance status on MRI phenotypes in MS. Mult Scler Relat Disord December 2024.
Gandelman S, Lenzi KA, Markowitz C, Berger JR.: A Proposed Approach to Screening and Surveillance Labs for Patients With Multiple Sclerosis on Anti-CD20 Therapy. Neurol Clin Pract 14(1), February 2024.
Coyle PK, Freedman MS, Cohen BA, Cree BAC, Markowitz CE.: Sphingosine 1-phosphate receptor modulators in multiple sclerosis treatment: A practical review. Ann Clin Transl Neurol 11(4): 842-855, April 2024.
Thebault S, Gandelman S, Lane C, Kim EJ, Pileggi C, Zuroff L, Yamashita LD, Schindler MK, Chiu C, Wilson MR, Berger JR, Markowitz C, Bar-Or A, Fuller R, Brandstadter R, Pruitt AA, Jacobs DA.: Severe Neuroinvasive West Nile Virus in Association With Anti-CD20 Monotherapy for Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm 10: e200154, Aug 2023.