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Brett L. Cucchiara, MD

Professor of Neurology at the Hospital of the University of Pennsylvania
Director, Neurovascular Ultrasound Laboratory, Hospital of the University of Pennsylvania
Department: Neurology

Contact information
Department of Neurology
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-662-6738
Fax: 215-349-5579
B.A. (English, magna cum laude)
Carleton College, 1992.
Tulane University School of Medicine, 1996.
Post-Graduate Training
Intern in Medicine, Tulane University School of Medicine, 1996-1997.
Resident in Neurology, Hospital of the University of Pennsylvania , 1997-2000.
Fellow in Stroke and Neurocritical Care, Hospital of the University of Pennsylvania, 2000-2001.
American Board of Psychiatry and Neurology (Neurology), 2001.
American Board of Psychiatry and Neurology (Vascular Neurology), 2006.
American Board of Psychiatry and Neurology (Neurology), Recertification, 2011.
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Description of Research Expertise

Current research involves studying 1) blood biomarkers in patients with transient ischemic attack (TIA), stroke, and other types of cerebrovascular disease, 2) alterations in vascular structure and function in patients with migraine, and 3) use of transcranial Doppler emboli detection for assessment of patients with cerebrovascular disease.

Description of Clinical Expertise

Cerebrovascular disease. Stroke. TIA. Intracerebral hemorrhage. Carotid stenosis. Arterial dissection. Transcranial Doppler.

Selected Publications

Cucchiara B, Datta, R, Aguirre G, Idoko K, Detre J. : Measurement of visual sensitivity in migraine – validation of two scales and correlation with visual cortex activation. Cephalalgia 35(7): 585-92, 2015.

Cucchiara B, Wolf RL, Nagae L, Zhang Q, Kasner S, Datta R, Aguirre GK, Detre JA.: Migraine with aura is associated with an incomplete circle of willis: results of a prospective observational study. PLoS ONE 8: e71007, 2013.

Datta R, Aguirre GK, Hu S, Detre JA, Cucchiara B.: Interictal cortical hyperresponsiveness in migraine is directly related to the presence of aura. Cephalalgia 33(6): 365-74, 2013.

Merwick A, Albers GW, Arsava EM, Ay H, Calvet D, Coutts SB, Cucchiara BL, Demchuk AM, Giles MF, Mas JL, Olivot JM, Purroy F, Rothwell PM, Saver JL, Sharma VK, Tsivgoulis G, Kelly PJ.: Reduction in early stroke risk in carotid stenosis with transient ischemic attack associated with statin treatment. Stroke. 44: 2814-2820, 2013.

Ishida K, Raser-Schramm JM, Wilson CA, Kasner SE, Mullen MT, Messe SR, Cucchiara B. : Convergent validity and interrater reliability of estimating the ABCD2 score from medical records. Stroke 44(3): 803-5, 2013.

Raser J, Cucchiara B.: Modifications of the ABCD2 score do not improve risk stratification of TIA patients. Journal of stroke and cerebrovascular diseases. 21(6): 467-70, Aug 2012.

Datta R, Detre JA, Aguirre GK, Cucchiara B.: Absence of changes in cortical thickness in patients with migraine. Cephalalgia. 31(14): 1452-8, Oct 2011.

Raser JM, Mullen MT, Kasner SE, Cucchiara BL, Messe SR. : Cervical carotid artery dissection is associated with styloid process length. Neurology. 77(23): 2061-66, Dec 2011.

Cucchiara BL, Messe SR, Sansing L, MacKenzie L, Taylor RA, Pacelli J, Shah Q, Kasner SE: Lipoprotein-associated phospholipase A2 and C-reactive protein for risk-stratification of patients with TIA. Stroke 40(7): 2332-6, Jul 2009.

Cucchiara, BL, Kasner, SE, Tanne, D, Levine, SR, Demchuk, AM, Messe, S, Sansing, LH, Lyden, P: Factors Associated With Post-Thrombolysis Intracerebral Hemorrhage-Pooled Analysis Of The SAINT-I And SAINT-II Trials. Stroke 40(4): E121, APR 2009.

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Last updated: 01/31/2024
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