Nicholas S. Abend, MD
Professor of Neurology at the Children's Hospital of Philadelphia
Medical Director, Clinical Neurophysiology, Children's Hospital of Philadelphia
Associate Scholar, Perelman School of Medicine at the University of Pennsylvania (Epidemiology Unit, Center for Clinical Epidemiology and Biostatistics)
Senior Medical Director, Neurology and Neurosurgery, Children's Hospital of Philadelphia (Neuroscience Center)
Core Faculty, Children’s Hospital of Philadelphia (Clinical Futures Center of Excellence; Center for Pediatric Clinical Effectiveness)
Distinguished Endowed Chair in the Department of Pediatrics, Children's Hospital of Philadelphia
Associate Chief for Inpatient Operations and Clinical Strategy, Division of Neurology, Children's Hospital of Philadelphia
Department: Neurology
Contact information
Children's Hospital of Philadelphia
Division of Neurology, HUB 10548
3501 Civic Center Blvd
Philadelphia, PA 19104
Division of Neurology, HUB 10548
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 215-590-1719
Fax: 215-590-1771
Fax: 215-590-1771
Email:
abend@chop.edu
abend@chop.edu
Education
BS
Washington University, 1998.
MD (Medicine)
University of Chicago School of Medicine, 2002.
MSCE (Clinical Epidemiology )
University of Pennsylvania School of Medicine, 2015.
BS
Washington University, 1998.
MD (Medicine)
University of Chicago School of Medicine, 2002.
MSCE (Clinical Epidemiology )
University of Pennsylvania School of Medicine, 2015.
Post-Graduate Training
Pediatrics Internship, University of Chicago Children's Hospital, 2002-2003.
Pediatrics Residency, University of Chicago Children's Hospital, 2003-2004.
Child Neurology Fellowship, Children’s Hospital of Philadelphia and the Hospital of University of Pennsylvania , 2004-2007.
Epidemiology and Biostatistics Certificate, University of Pennsylvania School of Medicine, 2007-2008.
Epilepsy and Clinical Neurophysiology Fellowship, Children's Hospital of Philadelphia, 2007-2009.
Certificate - Development in Leadership, Wharton School of Business, University of Pennsylvania, 2014-2016.
Certificate - Healthcare Innovation, School of Medicine, University of Pennsylvania, 2019-2020.
Pediatrics Internship, University of Chicago Children's Hospital, 2002-2003.
Pediatrics Residency, University of Chicago Children's Hospital, 2003-2004.
Child Neurology Fellowship, Children’s Hospital of Philadelphia and the Hospital of University of Pennsylvania , 2004-2007.
Epidemiology and Biostatistics Certificate, University of Pennsylvania School of Medicine, 2007-2008.
Epilepsy and Clinical Neurophysiology Fellowship, Children's Hospital of Philadelphia, 2007-2009.
Certificate - Development in Leadership, Wharton School of Business, University of Pennsylvania, 2014-2016.
Certificate - Healthcare Innovation, School of Medicine, University of Pennsylvania, 2019-2020.
Certifications
Neurology (with special qualification in child neurology) - American Board of Psychiatry and Neurology, 2008.
Epilepsy - American Board of Psychiatry and Neurology, 2012.
Permanent linkNeurology (with special qualification in child neurology) - American Board of Psychiatry and Neurology, 2008.
Epilepsy - American Board of Psychiatry and Neurology, 2012.
Description of Research Expertise
Pediatric EpilepsyEEG Monitoring in Critically Ill Children and Neonates
Management of Pediatric Status Epilepticus
Description of Clinical Expertise
Pediatric EpilepsyPediatric Electroencephalography
Description of Other Expertise
Quality ImprovementSelected Publications
Molisani SE, Kaufman MC, Tencer J, Fitzgerald M, Witzman S, Gonzalez A, Ramos M, DiGiovine M, Kessler SK, McDonnel PP, McKee J, Melamed S, Prelack M, Tefft S, Abend NS.: Medication Barriers in Pediatric Patients with Epilepsy. Pediatric Neurology 177: 140-147, 2026.Mazzio E, Catenaccio E, Liu R, Vossough A, Abend NS, Alcamo A, Huh J, Chen SS, Berg RA, Topjian A, Press C, Kirschen MP.: Association of EEG Response to Hypertonic Saline and Neurologic Outcomes in Pediatric Acute Brain Injury. Neurocritical Care 44(3): 841-849, 2026.
Marshall A, Kaufman MC, Murphy C, Molisani SE, Riisen AC, Scotti-Degnan CM, Witzman S, Gonzalez AK, Ramos MO, Szperka CL, Abend NS.: Screening for Anxiety Symptoms with the GAD-2 versus GAD-7 in Children with Headache or Epilepsy. Pediatric Neurology 178: 7--14, 2026.
Essaid L, Haque K, Shillingford A, Zimmerman L, Burnham A, Hampton L, Okunowo O, Gaynor JW, Abend NS, Naim MY, Gardner MM. : Medical and Socioeconomic Risk Factors Associated with Lack of Neurodevelopmental Evaluation Following Neonatal Cardiac Surgery. Pediatric Cardiology 47(1): 257-265, 2026.
Silva LEV, Chen CC, Press CA, Graham K, Shi L, Abend NS, Morgan RW, Topjian A, Tsui F, Kirschen MP. : Pediatric cardiac arrest outcome prediction using data-driven machine learning of early quantitative electroencephalogram (qEEG) features. Resuscitation 201(110854), 2025.
Becker AE, Abend NS, Benedetti GM, Buttram SDW, Chung MG, Erklauer JC, Friess SH, Hong SJ, Huh J, Kirschen MP, LaRovere KL, Lovett ME, Schober ME, Smith KA, Wolfe K, Zurca AD, Topjian AA, Boyer DL.: Neurocritical Care Entrustable Professional Activities for Pediatric Critical Care Medicine Education and Professional Development. Pediatric Critical Care Medicine 26(11): e1394-e1402, 2025.
Silver MR, Caffee L, Fried LE, Gonzalez AK, Huber R, Kaufman MC, Means M, Patel N, Ramos M, Witzman S, Beam K, Zook J, Abend NS, Press C, Molisani S.: A Quality Improvement Initiative to Reduce Underdosing of Rectal Diazepam as Home Seizure Rescue Medication after Hospitalization. Neurology in Clinical Practice 15(5): e200529, 2025.
Ostendorf AP, Loddenkemper T, Morgan LA, Appavu B, Farias-Moeller R, Harrar D, Press C, Abend NS, Gaillard WD, Bai S, Eisner M, McHenry L, Kroshus E, Vannatta K, Goodkin HP. : Treating seizures faster: The quality improvement in time to treat status epilepticus (QuITT-SE) multicenter randomized stepped-wedge clinical trial protocol. Contemporary Clinical Trials 151: 107831, 2025.
Murphy C, Molisani SE, Riisen AC, Scotti-Degnan CM, Karvounides D, Witzman S, Kaufman MC, Gonzalez AK, Ramos, MO, Szperka CL, Abend NS. : A Quality Improvement Initiative to Implement Anxiety Screening to Children and Teens with Headache and Epilepsy. Neurology in Clinical Practice 15(3): e200458, 2025.
Massey SL, Sandoval Karamanian AG, Fitzgerald MP, Fung FW, Abramson A, Salmon MK, Parikh D, Abend NS.: Development of a Model to Predict Electroencephalographic Seizures in Neonates with Hypoxic Ischemic Encephalopathy Treated with Therapeutic Hypothermia. Epilepsia 66(2), 518-530 2025.