Christopher G Favilla, MD
Associate Professor of Neurology at the Hospital of the University of Pennsylvania
Director, Non-Invasive Cerebral Hemodynamic Evaluation (NICHE) Center
Department: Neurology
Contact information
Hospital of the University of Pennsylvania, Dept. of Neurology
3400 Spruce Street, 3 West Gates Building
Philadelphia, PA 19146
3400 Spruce Street, 3 West Gates Building
Philadelphia, PA 19146
Office: 2156153727
Fax: 2153495579
Fax: 2153495579
Education:
BA
University of Pennsylvania, 2007.
MD
University of Florida College of Medicine, 2012.
BA
University of Pennsylvania, 2007.
MD
University of Florida College of Medicine, 2012.
Post-Graduate Training
Doris Duke Clinical Research Fellowship, University of Pennsylvania , 2009-2010.
Intern in Medicine, Hospital of the University of Pennsylvania, 2012-2013.
Resident in Neurology, Hospital of the University of Pennsylvania, 2013-2016.
Fellow in Vascular Neurology , Hospital of the University of Pennsylvania, 2016-2017.
Doris Duke Clinical Research Fellowship, University of Pennsylvania , 2009-2010.
Intern in Medicine, Hospital of the University of Pennsylvania, 2012-2013.
Resident in Neurology, Hospital of the University of Pennsylvania, 2013-2016.
Fellow in Vascular Neurology , Hospital of the University of Pennsylvania, 2016-2017.
Certifications
American Board of Psychiatry and Neurology, 2016.
American Board of Psychiatry and Neurology - Vascular Neurology, 2018.
Permanent linkAmerican Board of Psychiatry and Neurology, 2016.
American Board of Psychiatry and Neurology - Vascular Neurology, 2018.
Description of Research Expertise
Dr. Favilla's research program focuses on the translation and adaptation of non-invasive imaging modalities to monitor cerebral hemodynamics at the bedside. His lab is particularly interested in developing biomarkers and treatment targets that will facilitate personalized care that optimizes cerebral hemodynamics.Selected Publications
Sarraj A, Thomalla G, Yoshimura S, Huo X, Costalat V, Zaidat OO, Arquizan C, Johns H, Yogendrakumar V, Churilov L, Pujara D, Sitton CW, Liebeskind DS, Inoue M, Majoie C, Beenen L, Abdulrazzak MA, Chaturvedi A, Singh S, Parsons MW, Denis A, Sakai N, Nguyen TN, Albucher JF, Kasab SA, Hassan AE, Abraham M, Rai A, Henon H, Sun D, Yamagami H, Subtil F, Bonekamp S, Uchida K, Yuan G, Gory B, Smith W, Ortega-Gutierrez S, Blackburn S, Sheth SA, Marnat G, Liu L, Shirakawa M, Fiehler J, Jensen M, Shindo S, Nogueira RG, Grandhi R, Jabbour P, Hussain MS, Dippel D, Wang Y, Yazawa Y, Simonsen CZ, Wang Y, Chen M, Hill MD, Grotta JC, Lapergue B, Jovin TG, Yoo AJ, Bendszus M, Campbell BCV, Morimoto T, Miao Z; ATLAS Investigators: Endovascular thrombectomy for patients with large-core ischaemic stroke presenting up to 24 h after onset (ATLAS): a systematic review and individual patient data meta-analysis with central imaging adjudication. Lancet 407(10543): 2015-2026, May 2026.Ghosh S, Dubow J, Favilla CG, Sutherland J, Kalmes A, Mock J, Chiu D, Clark WM, Ansari SA, Nicodemus-Johnson J, Anderson L, Liebeskind DS, Fisher M, McTaggart RA: RNS60 RESCUE Trial in Acute Ischemic Stroke: Post Hoc Analysis in Participants Enrolled <12 Hours Since Last Known Well. Stroke Vasc Interv Neurol 6(3): e002196, Apr 2026.
Broderick JP, Mistry EA, Wechsler PM, Elkind MSV, Liebeskind DS, Harston G, Wolenberg J, Frontera JA, Kimberly WT, Favilla CG, Boltze J, Ospel J, Samaniego EA, Adeoye O, Kasner SE, Schwamm LH, Albers GW; Stroke Treatment Academic Industry Roundtable XIII Participants: Artificial Intelligence and Novel Trial Designs for Acute Ischemic Stroke: Opportunities and Challenges. Stroke 57(1): 265-274, Feb 2026.
Campbell BCV, Aziz YN, Harston GWJ, Adeoye O, Khatri P, Fischer U, Xiong Y, Alexandrov AV, Makris GC, Baron JC, Ng FC, Ter Schiphorst A, Nguyen TN, Ortega-Gutierrez S, Maier C, Liu L, Hill MD, Albers GW, Heit JJ; STAIR XIII Consortium: Optimizing Reperfusion Trials: A Consensus Research Roadmap From the STAIR XIII Conference. Stroke 57(2): 514-525, Feb 2026.
Zuflacht J, Miller J, Ljungberg L, Little J, Zhou S, Messe S, Favilla C, Cucchiara B, Kasner SE: Role of CT Perfusion Imaging in Patients With Minor Stroke: A Cohort Study. Neurohospitalist online ahead of print, Jan 2026.
Wu AQ, Gitlevich R, Palepu C, Hoglund ZT, Sollenberger CH, Kahlon AS, Scott KW, Ehtiati T, Burkhardt JK, Catapano JS, Kandregula S, Favilla CG, Srinivasan VM: Mapping real-time hemodynamic changes in venous sinus stenting using intraoperative transcranial Doppler ultrasonography and quantitative angiography. Neurosurg Focus 60(1): E10, Jan 2026.
Favilla CG: Clinical Applications of Optical Cerebral Blood Flow Imaging. Inside Scientific Jan 2026 Notes: webinar.
Ghosh S, Dubow JS, Sutherland J, Smith W, Chiu D, Clark WM, Favilla CG, Ansari SA, Kalmes A, Mock J, Cook DJ, Madsen TE, Jayaraman M, Moldovan K, Torabi R, Liebeskind DS, Fisher M, McTaggart RA: Randomized, Proof-of-Concept Trial (RESCUE) of RNS60 as an Adjunct Therapy in Acute Ischemic Stroke. Stroke 56(9): 2386-2397, Sep 2025.
Favilla CG, Mullen MT, Konecky S, McCardell T, McTaggart RA, Baird GL: Pre-hospital LVO detection: One size does not fit all. J Stroke Cerebrovasc Dis 34(7), Jul 2025.
Sarraj A, Blackburn S, Abraham MG, Hussain MS, Ortega-Gutierrez S, Chen M, Kasner SE, Churilov L, Sitton CW, Pujara DK, Sundararajan S, Hu YC, Herial NA, Budzik RF, Hicks WJ, Vora N, Arenillas JF, Alfonso ML, Ramos Araque ME, Tsai JP, Abdulrazzak MA, Kozak O, Yan B, Mitchell PJ, Cordato DJ, Manning NW, Cheung A, Hanel RA, Aghaebrahim AN, Wu TY, Portela PC, Merchán AJP, Gandhi CD, Al-Mufti F, Samaniego EA, Maali L, Qureshi A, Lechtenberg CG, Slavin S, Rosterman L, Gibson D, Wallace AN, Sahlein D, Pérez de la Ossa N, Hernández Pérez M, Schaafsma JD, Blasco J, Renú A, Sangha N, Warach S, Kleinig TJ, Mullen M, Elijovich L, Shaker F, Al-Shaibi FK, Johns H, Duncan KR, Opaskar A, Popovic MJ, Altose M, Ray A, Xiong W, Sunshine J, DeGeorgia M, Nguyen TN, Fifi JT, Tjoumakaris S, Jabbour P, Pereira VM, Lansberg MG, Albers GW, Sila C, Bambakidis N, Davis S, Wechsler L, Hill MD, Grotta JC, Ribo M, Hassan AE, Campbell BC; SELECT2 Investigators.: General vs Nongeneral Anesthesia for Endovascular Thrombectomy in Patients With Large Core Strokes: A Prespecified Secondary Analysis of SELECT2 Trial. Neurology 105(2): e213819, Jul 2025.