Michael Gelfand, MD, PhD
Associate Professor of Clinical Neurology
Department: Neurology
Contact information
Department of Neurology
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104-4283
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104-4283
Office: 215-662-3606
Education:
BS & MS (Molecular Biophysics and Biochemistry )
Yale University, 2001.
PhD (Neuroscience)
Rockefeller University, 2009.
MD (Doctor of Medicine)
Weill Cornell Medical College, 2010.
BS & MS (Molecular Biophysics and Biochemistry )
Yale University, 2001.
PhD (Neuroscience)
Rockefeller University, 2009.
MD (Doctor of Medicine)
Weill Cornell Medical College, 2010.
Post-Graduate Training
Intern in Medicine, St. Luke`s-Roosevelt Hospital Center, New York, NY, 2010-2011.
Resident in Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2011-2014.
Fellow in Epilepsy/Neurophysiology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2014-2015.
Intern in Medicine, St. Luke`s-Roosevelt Hospital Center, New York, NY, 2010-2011.
Resident in Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2011-2014.
Fellow in Epilepsy/Neurophysiology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2014-2015.
Certifications
Neurology (American Board of Psychiatry and Neurology(ABPN)), 2014.
Epilepsy (American Board of Psychiatry and Neurology(ABPN)), 2016.
Permanent linkNeurology (American Board of Psychiatry and Neurology(ABPN)), 2014.
Epilepsy (American Board of Psychiatry and Neurology(ABPN)), 2016.
Description of Clinical Expertise
Epilepsy, EEG, Clinical Neurophysiology, Epilepsy Surgery, Antiepileptic Drugs, ElectrocorticographyDescription of Research Expertise
Clinical TrialsSelected Publications
Barnard SN, Chen Z, Holmes M, Kanner AM, Hegde M, Kuzniecky R, Lowenstein D, French JA; Human Epilepsy Project (1) Investigators.: Treatment Response to Antiseizure Medications in People With Newly Diagnosed Focal Epilepsy. JAMA Neurol Aug 2025.Xie K, Korzun J, Zhou DJ, Chang E, Ghosn NJ, Lavelle S, Oganisian A, Acton EK, Gelfand MA, Roth D, Litt B, Ellis CA.: Comparative effectiveness of anti-seizure medications in emulated trials using medical informatics. Brain Jul 2025.
Xu Z, Scheid BH, Conrad EC, Davis KA, Ganguly T, Gelfand MA, Gugger JJ, Jiang X, LaRocque JJ, Ojemann WKS, Sinha SR, Waldman GJ, Wagenaar J, Sinha N, Litt B.: Annotating neurophysiologic data at scale with optimized human input. J Neural Eng 22: 046003, Jul 2025.
Dave H, Sperling MR, Altalib HH, Henninger H, Porter RJ, Gelfand M, Dongre P, Elmoufti S, Martin MS, Schulz AL, French JA.: Brivaracetam effectiveness and patient-reported outcomes in clinical practice: Data from a 12-month prospective, observational study in the United States. Epilepsy Behav 173: 110565, Jul 2025.
Alkofer M, Yang C, Ganglberger W, Beal J, Hegde M, Kang JY, Yoo JY, Gelfand MA, Thio LL, Kutluay E, Campbell Z, Schmitt S, Gleichgerrcht E, Waterhouse E, Lopez MR, Eisenschenk S, Galanti M, Singh RK, Wills KE, Meulenbrugge EJ, Dlugos D, Dean B, Halford JJ, Goldenholz D, Jing J, Thomas R, Westover MB.: Automated detection of interictal epileptiform discharges with few electroencephalographic channels. Epilepsia 66: e114-20, May 2025.
French JA, Porter RJ, Perucca E, Brodie MJ, Rogawski MA, Harden C, Qian J, Rosenblut CL, Kenney C, Beatch GN; X‐TOLE Study Group.: Interim analysis of the long-term efficacy and safety of azetukalner in an ongoing open-label extension study following a phase 2b clinical trial (X-TOLE) in adults with focal epilepsy. Epilepsia Open 2025.
Barnard SN, Chen Z, Kanner AM, Holmes MG, Klein P, Abou-Khalil BW, Gidal BE, French J, Perucca P; Human Epilepsy Project.: The Adverse Effects of Commonly Prescribed Antiseizure Medications in Adults With Newly Diagnosed Focal Epilepsy. Neurology 103: e209821, Oct 2024.
Acton EK, Hennessy S, Gelfand MA, Leonard CE, Bilker WB, Shu D, Willis AW, Kasner SE.: Direct-Acting Oral Anticoagulants and Antiseizure Medications for Atrial Fibrillation and Epilepsy and Risk of Thromboembolic Events. JAMA Neurol 81: 835-844, Aug 2024.
Greenwood HT, French J, Ferrer M, Jandhyala N, Thio LL, Dlugos DJ, Park KL, Kanner AM; Human Epilepsy Project Investigators.: Prevalence of Suicidality in Adolescents With Newly Diagnosed Focal Epilepsy at Diagnosis and Over the Following 36 Months. Neurology 103: e209397, Jul 2024.
Emmert BE, Xie K, Conrad EC, Ghosn NJ, Bauman K, Korzun J, Kulick-Soper CV, Naveed O, Hartmann N, LaRocque JJ, Mindy Ganguly T, Gugger JJ, Raghupathi R, Gelfand MA, Davis KA, Sinha SR, Litt B, Shinohara RT, Ellis CA.: Alcohol for seizure induction in the epilepsy monitoring unit. Epilepsy Behav 2024.