faculty photo

Michael Gelfand, MD, PhD

Associate Professor of Clinical Neurology
Department: Neurology

Contact information
Department of Neurology
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104-4283
Office: 215-662-3606
Education:
BS & MS (Molecular Biophysics and Biochemistry )
Yale University, 2001.
PhD (Neuroscience)
Rockefeller University, 2009.
MD (Doctor of Medicine)
Weill Cornell Medical College, 2010.
Post-Graduate Training
Intern in Medicine, St. Luke`s-Roosevelt Hospital Center, New York, NY, 2010-2011.
Resident in Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2011-2014.
Fellow in Epilepsy/Neurophysiology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2014-2015.
Certifications
Neurology (American Board of Psychiatry and Neurology(ABPN)), 2014.
Epilepsy (American Board of Psychiatry and Neurology(ABPN)), 2016.
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Description of Clinical Expertise

Epilepsy, EEG, Clinical Neurophysiology, Epilepsy Surgery, Antiepileptic Drugs, Electrocorticography

Description of Research Expertise

Clinical Trials

Selected Publications

Emmert BE, Xie K, Conrad EC, Ghosn NJ, Bauman K, Korzun J, Kulick-Soper CV, Naveed O, Hartmann N, LaRocque JJ, Mindy Ganguly T, Gugger JJ, Raghupathi R, Gelfand MA, Davis KA, Sinha SR, Litt B, Shinohara RT, Ellis CA.: Alcohol for seizure induction in the epilepsy monitoring unit. Epilepsy Behav 2024.

French JA, Porter RJ, Perucca E, Brodie MJ, Rogawski MA, Pimstone S, Aycardi E, Harden C, Qian J, Rosenblut CL, Kenney C, Beatch GN; X-TOLE Study Group.: Efficacy and Safety of XEN1101, a Novel Potassium Channel Opener, in Adults With Focal Epilepsy: A Phase 2b Randomized Clinical Trial. JAMA Neurol 80: 1145-1154, Nov 2023.

Bases B, Barnard S, French JA, Pellinen J; Human Epilepsy Project.: Impact of Seizures While Driving Prior to Diagnosis in People With Focal Epilepsy: Motor Vehicle Accidents and Time to Diagnosis. Neurology 101: e1370-e1375, Sep 2023.

Kanner AM, Saporta AS, Kim DH, Barry JJ, Altalib H, Omotola H, Jette N, O'Brien TJ, Nadkarni S, Winawer MR, Sperling M, French JA, Abou-Khalil B, Alldredge B, Bebin M, Cascino GD, Cole AJ, Cook MJ, Detyniecki K, Devinsky O, Dlugos D, Faught E, Ficker D, Fields M, Gidal B, Gelfand M, Glynn S, Halford JJ, Haut S, Hegde M, Holmes MG, Kalviainen R, Kang J, Klein P, Knowlton RC, Krishnamurthy K, Kuzniecky R, Kwan P, Lowenstein DH, Marcuse L, Meador KJ, Mintzer S, Pardoe HR, Park K, Penovich P, Singh RK, Somerville E, Szabo CA, Szaflarski JP, Lin Thio KL, Trinka E, Burneo JG; Human Epilepsy Project.: Mood and Anxiety Disorders and Suicidality in Patients With Newly Diagnosed Focal Epilepsy: An Analysis of a Complex Comorbidity. Neurology 100: e1123-e1134, Mar 2023.

French J, Biton V, Dave H, Detyniecki K, Gelfand MA, Gong H, Liow K, O'Brien TJ, Sadek A, DiVentura B, Reich B, Isojarvi J.: A randomized phase 2b efficacy study in patients with seizure episodes with a predictable pattern using Staccato® alprazolam for rapid seizure termination. Epilepsia 2023.

Pellinen J, Pardoe H, Sillau S, Barnard S, French J, Knowlton R, Lowenstein D, Cascino GD, Glynn S, Jackson G, Szaflarski J, Morrison C, Meador KJ, Kuzniecky R; Human Epilepsy Project Investigators.: Later onset focal epilepsy with roots in childhood: Evidence from early learning difficulty and brain volumes in the Human Epilepsy Project. Epilepsia 2023.

Hina Dave, MD - UT Southwestern Medical Center; Jacqueline French, MD - NYU Comprehensive Epilepsy Center; Hamada Hamid Altalib, DO, MPH, FAES - Yale University; Heidi Henninger, MD - Maine Medical Center; Roger Porter, MD, ScD - Perelman School of Medicine, University of Pennsylvania; Michael Gelfand, MD, PhD - University of Pennsylvania; Melinda Martin, PhD - UCB Pharma, Smyrna; Prashant Dongre, MD - UCB Pharma, Smyrna; Sami Elmoufti, MS - UCB Pharma, Raleigh; Anne-Liv Schulz, MD - UCB Pharma, Monheim am Rhein; Michael Sperling, MD - Thomas Jefferson University: Real-World Study of Brivaracetam in the United States. American Epilepsy Society December 2021.

Heidi Henninger, MD - Maine Medical Center; Michael Sperling, MD – Thomas Jefferson University; Hamada Hamid Altalib, DO, MPH – Yale University; Hina Dave, MD – University of Texas Southwestern Medical Center; Michael Gelfand, MD, PhD – University of Pennsylvania; Roger Porter, MD - University of Pennsylvania; Melinda Martin, PhD – UCB Pharma, Smyrna; Sami Elmoufti, MS – UCB Pharma, Raleigh; Anne-Liv Schulz, MD – UCB Pharma, Monheim am Rhein; Prashant Dongre, MD – UCB Pharma, Smyrna; Jacqueline French, MD – NYU Comprehensive Epilepsy Center: Effectiveness and Tolerability of Brivaracetam by Reason for Initiation in Adults with Focal Seizures: Post-hoc Analysis of a Real-world, US Study. American Epilepsy Society December 2021.

Manisha Holmes; aaron smith; Dennis Dlugos; Michael Gelfand; tricia Ting; Orrin Devinsky; Jacqueline French: Differentiating Generalized Epilepsy vs Focal Epilepsy with Secondary Bilateral Synchrony in Newly Diagnosed Patients. American Epilepsy Society December 2021.

Syndi Seinfeld, DO - Joe DiMaggio Children’s Hospital; Carla Buan - Aquestive Therapeutics; Michael Gelfand - University of Pennsylvania; Allen Heller - Pharma Study Design, LLC; Ayman Kafal - Aquestive Therapeutics; gary Slatko - Aquestive Therapeutics: Diazepam Buccal Film (DBF): Final Results from a Phase 3, Open-Label, Safety and Tolerability Study of Chronic Intermittent Use in Pediatric, Adolescent and Adult Subjects with Epilepsy. American Epilepsy Society December 2021.

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Last updated: 01/18/2024
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