faculty photo

Lauren Elman, MD

Professor of Neurology at the Hospital of the University of Pennsylvania and the Pennsylvania Hospital
Director of the Muscular Dystrophy Association Clinic, University of Pennsylvania Medical Center
Director of the Penn Comprehensive Amyotrophic Lateral Sclerosis Center, University of Pennsylvania Medical Center
Associate Director and Clinical Lead of the Translational Center of Excellence, University of Pennsylvania Medical Center
Department: Neurology

Contact information
Pennsylvania Hospital
330 South 9th Street
Philadelphia, PA 19107
Office: 215-829-6708
Fax: 215-829-6606
BA (Psychology)
Cornell University, 1994.
MD (Medicine)
Cornell University Medical College, 1998.
Post-Graduate Training
Medicine Internship, Hospital of the University of Pennsylvania, 1998-1999.
Neurology Residency, Hospital of the University of Pennsylvania, 1999-2002.
Neuromuscular Fellowship, Hospital of the Universityof Pennsylvania, 2002-2004.
Clinical Research Certificate Program, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 2003-2005.
American Board of Psychiatry and Neurology, 2003.
American Board of Psychiatry and Neurology, Maintenance of Certification, 2013.
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Selected Publications

Mitsumoto H, Jang G, Lee I, Simmons Z, Sherman AV, Heitzman D, Sorenson E, Cheung K, Andrews J, Harms M, Shneider NA, Santella R, Paganoni S, Ajroud-Driss S, Fernandes JAM, Burke KM, Gwathmey K, Habib AA, Maragakis NJ, Walk D, Fournier C, Heiman-Patterson T, Wymer J, Diaz F, Scelsa SN, Elman L, Genge A, Goutman SA, Hayat G, Jawdat O, Johnston WS, Joyce NC, Kasarskis EJ, Kisanuki YY, Lomen-Hoerth C, Pulley MT, Shah JS, Shoesmith C, Zinman L; PLS Natural History Study Group.: Primary lateral sclerosis natural history study - planning, designing, and early enrollment. Amyotroph Lateral Scler Frontotemporal Degener December 2022.

McMillan CT, Wuu J, Rascovsky K, Cosentino S, Grossman M, Elman L, Quinn C, Rosario L, Stark JH, Granit V, Briemberg H, Chenji S, Dionne A, Genge A, Johnston W, Korngut L, Shoesmith C, Zinman L; Canadian ALS Neuroimaging Consortium (CALSNIC); Kalra S, Benatar M: Defining cognitive impairment in amyotrophic lateral sclerosis: an evaluation of empirical approaches. Amyotroph Lateral Scler Frontotemporal Degener November 2022.

Cousins KAQ, Shaw LM, Shellikeri S, Dratch L, Rosario L, Elman LB, Quinn C, Amado DA, Wolk DA, Tropea TF, Chen-Plotkin A, Irwin DJ, Grossman M, Lee EB, Trojanowski JQ, McMillan CT: Elevated Plasma Phosphorylated Tau 181 in Amyotrophic Lateral Sclerosis. Ann Neurol November 2022.

Ramos-Platt L, Elman L, Shieh PB: Experience and Perspectives in the US on the Evolving Treatment Landscape in Spinal Muscular Atrophy. Int J Gen Med September 2022.

Statland JM, Campbell C, Desai U, Karam C, Díaz-Manera J, Guptill JT, Korngut L, Genge A, Tawil RN, Elman L, Joyce NC, Wagner KR, Manousakis G, Amato AA, Butterfield RJ, Shieh PB, Wicklund M, Gamez J, Bodkin C, Pestronk A, Weihl CC, Vilchez-Padilla JJ, Johnson NE, Mathews KD, Miller B, Leneus A, Fowler M, van de Rijn M, Attie KM: Randomized phase 2 study of ACE-083, a muscle-promoting agent, in facioscapulohumeral muscular dystrophy. Muscle Nerve July 2022.

Ohm DT, Cousins KAQ, Xie SX, Peterson C, McMillan CT, Massimo L, Raskovsky K, Wolk DA, Van Deerlin VM, Elman L, Spindler M, Deik A, Trojanowski JQ, Lee EB, Grossman M, Irwin DJ: Signature laminar distributions of pathology in frontotemporal lobar degeneration. Acta Neuropathol March 2022.

Elman L, Youn B, Proud CM, Frey MR, Ajroud-Driss S, McCormick ME, Michelson D, Cartwright MS, Heiman-Patterson T, Choi JM, Chandak A, Khachatryan A, Martinez M, Paradis AD: Real-world Adherence to Nusinersen in Adults with Spinal Muscular Atrophy in the US: A Multi-site Chart Review Study. J Neuromuscul Dis. 2022.

Mao F, Robinson JL, Unger T, Posavi M, Amado DA, Elman L, Grossman M, Wok DA, Lee EB, Van Deerlin VM, Porta S, Lee V M-Y, Trojanowski JQ, Chen-Plotkin AS.: TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy. Acta Neuropathol June 2021.

Guo M, Bardakjian TM, Brzozowski MR, Scherer SS, Quinn C, Elman L, Orthmann-Murphy J, Tropea TF, Ellis CA, Gonzlaz-Alegre P.: Temporal trends and yield of clinical diagnostic genetic testing in adult neurology. Am J Med Genet A 185(10): 2922-2928, June 2021.

Zhang JV, Irwin DJ, Blennow K, Zetterberg H, Lee EB, Shaw LM, Rascovsky K, Massimo L, McMillan CT, Chen-Plotkin A, Elman L, Lee VM, McCluskey L, Toledo JB, Weintraub D, Wolk D, Trojanowski JQ, Grossman M.: Neurofilament Light Chain Related to Longitudinal Decline in Frontotemporal Lobar Degeneration. Neurol Clin Pract 11(2): 105-116, Apr 2021.

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Last updated: 02/21/2023
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