Danielle Sandsmark, MD, PhD
Associate Professor of Neurology at the Hospital of the University of Pennsylvania
Director of Neurocritical Care Research, University of Pennsylvania
Program Director of Neurocritical Care Fellowship , University of Pennsylvania
Co-Director, Penn Acute Care Research Collaborative
Department: Neurology
Contact information
Department of Neurology
Perelman School of Medicine University of Pennsylvania
3400 Spruce St
3 West Gates Building
Philadelphia, PA 19104
Perelman School of Medicine University of Pennsylvania
3400 Spruce St
3 West Gates Building
Philadelphia, PA 19104
Education:
B.A. (Molecular Biology)
Coe College, Cedar Rapids, Iowa, 2001.
Ph.D. (Neurosciences)
Washington University School of Medicine, St. Louis, MO, 2006.
M.D. (Medical Doctorate)
Washington University School of Medicine, St. Louis, MO, 2008.
B.A. (Molecular Biology)
Coe College, Cedar Rapids, Iowa, 2001.
Ph.D. (Neurosciences)
Washington University School of Medicine, St. Louis, MO, 2006.
M.D. (Medical Doctorate)
Washington University School of Medicine, St. Louis, MO, 2008.
Post-Graduate Training
Intern, Internal Medicine, Barnes-Jewish Hospital, St. Louis, MO, 2008-2009.
Resident, Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2009-2012.
Fellow, Neurocritical Care, Hospital of the University of Pennsylvania, Philadelphia, PA, 2012-2014.
Intern, Internal Medicine, Barnes-Jewish Hospital, St. Louis, MO, 2008-2009.
Resident, Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2009-2012.
Fellow, Neurocritical Care, Hospital of the University of Pennsylvania, Philadelphia, PA, 2012-2014.
Certifications
American Board of Neurology and Psychiatry, 2013.
United Council for Neurological Subspecialties, 2015.
Permanent linkAmerican Board of Neurology and Psychiatry, 2013.
United Council for Neurological Subspecialties, 2015.
Selected Publications
Flanigan, M Zhou, J Sandsmark, DK: Traumatic Brain Injury. The Practice of Neurocritical Care Benjamin Tan, MD (eds.). Neurocritical Care Society 2026.Jed A. Hartings, Laura B. Ngwenya, Jennifer Goldthwait, Danielle Sandsmark, Ediberto Amorim De Cerqueira Filho, Britta Lindquist, Jens P. Dreier, Brandon Foreman: Feasibility Trial of Spreading Depolarization Monitoring to Guide Management of Severe Traumatic Brain Injury: Initial Results. American Academy of Neurology Annual Meeting 2026.
Trevor McCutcheon, Justin Desprebiteres, Amber Erich, Kate Deppen, Stefanie Darnley, Danielle Sandsmark, Ramon Diaz-Arrastia, Vidyulata Kamath, Jeffrey Ware, Andrea L.C. Schneider, Alexa Walter: Subjective and Objective Findings of Anosmia are Discordant and Persist for 6 months in Hospitalized Individuals with Traumatic Brain Injury. American Academy of Neurology Annual Meeting 2026.
Nuala J. Meyer Rogan Magee John P. Reilly Ali Kamal James C. Jackson E Wesley Ely Jillian Rhoads Matthew Shotwell Samuel M. Brown Carolyn S. Calfee Michael O. Harhay Robert Hyzy Marc Moss Lorraine B. Ware Wesley H. Self Michelle N. Gong Dale M. Neeham Sarah J. Beesley Mihir R. Atreya Kathleen A. Stringer Pratik Sinha Angela J. Rogers Joseph A. Hippensteel Danielle K. Sandsmark : Plasma tau and neurofilament light chain, markers of neuronal injury, associate with delirium duration, survival, and subjective cognitive complaints in the ARDS, Pneumonia, and Sepsis Consortium. American Thoracic Society Annual Meeting 2026.
De Boer, Christopher Sandsmark, Danielle Pascual, Jose: Bedside neurologic monitoring Principles of Adult Surgical Critical Care. Springer Nature, 2025.
Andrea L. C. Schneider, MD, PhD1 Katherine J. Hunzinger, PhD Benjamin L. Brett, PhD Danielle K. Sandsmark, MD, PhD Sonia Jain, PhD Xiaoying Sun, MS Raquel C. Gardner, MD Geoffrey T. Manley, MD, PhD Ramon Diaz-Arrastia, MD, PhD Lindsay D. Nelson, PhD and the TRACK-TBI Study Investigators: Vascular Risk Factors and 1-Year Cognitive Change Among Individuals With Traumatic Brain Injury. JAMA Network Open 8: e2525719, 2025.
Yamashita, Luana Manning, Sara Kolson, Dennis Sandsmark, Danielle Desai, Neel M Manning, Abigail Pileggi, Caitlin Schindler, Matthew : Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro-COVID Clinic. Annals of Clinical and Translational Neurology 2025.
Magee, R Shen, J Walter, AE Schneider, ALC Puccio, AM Lynch, CE Diaz-Arrastia, R Sandsmark, DK: MiRNAs detected in whole blood following traumatic brain injury are associated with recovery 6 months after injury Neurotrauma Reports 2025.
Walter AE, Savalia K, Yoon J , Morrison J, Schneider ALC, Diaz-Arrastia R, and Sandsmark DK.: Change in enlarged perivascular spaces over time and associations with outcomes after traumatic brain injury Neurotrauma Reports 5(1): 738-748, July 2024.
Silverman, EL Sandsmark, DK Field, RI : Assessment of Resident Physician Comfort in Screening for Social Determinants of Health in a Specialty Clinic Population. The Journal of Law, Medicine & Ethics. DOI: 10.1017/jme.2024.22, 51: 874-879, 2024.