Danielle Sandsmark, MD, PhD
Associate Professor of Neurology at the Hospital of the University of Pennsylvania
Director of Neurocritical Care Research, University of Pennsylvania
Program Director of Neurocritical Care Fellowship , University of Pennsylvania
Co-Director, Penn Acute Care Research Collaborative
Department: Neurology
Contact information
Department of Neurology
Perelman School of Medicine University of Pennsylvania
3400 Spruce St
3 West Gates Building
Philadelphia, PA 19104
Perelman School of Medicine University of Pennsylvania
3400 Spruce St
3 West Gates Building
Philadelphia, PA 19104
Education:
B.A. (Molecular Biology)
Coe College, Cedar Rapids, Iowa, 2001.
Ph.D. (Neurosciences)
Washington University School of Medicine, St. Louis, MO, 2006.
M.D. (Medical Doctorate)
Washington University School of Medicine, St. Louis, MO, 2008.
B.A. (Molecular Biology)
Coe College, Cedar Rapids, Iowa, 2001.
Ph.D. (Neurosciences)
Washington University School of Medicine, St. Louis, MO, 2006.
M.D. (Medical Doctorate)
Washington University School of Medicine, St. Louis, MO, 2008.
Post-Graduate Training
Intern, Internal Medicine, Barnes-Jewish Hospital, St. Louis, MO, 2008-2009.
Resident, Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2009-2012.
Fellow, Neurocritical Care, Hospital of the University of Pennsylvania, Philadelphia, PA, 2012-2014.
Intern, Internal Medicine, Barnes-Jewish Hospital, St. Louis, MO, 2008-2009.
Resident, Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2009-2012.
Fellow, Neurocritical Care, Hospital of the University of Pennsylvania, Philadelphia, PA, 2012-2014.
Certifications
American Board of Neurology and Psychiatry, 2013.
United Council for Neurological Subspecialties, 2015.
Permanent linkAmerican Board of Neurology and Psychiatry, 2013.
United Council for Neurological Subspecialties, 2015.
Selected Publications
Flanigan, M Zhou, J Sandsmark, DK: Traumatic Brain Injury. The Practice of Neurocritical Care Benjamin Tan, MD (eds.). Neurocritical Care Society 2026.Jed A. Hartings, Laura B. Ngwenya, Jennifer Goldthwait, Danielle Sandsmark, Ediberto Amorim De Cerqueira Filho, Britta Lindquist, Jens P. Dreier, Brandon Foreman: Feasibility Trial of Spreading Depolarization Monitoring to Guide Management of Severe Traumatic Brain Injury: Initial Results. American Academy of Neurology Annual Meeting 2026.
Self WH, Calfee CS, Brown SM, Moss M, Ware LB, Hyzy RC, Meyer NJ, Reilly JP, Harhay MO, Shashaty MG, Sandsmark DK, Auriemma CL, Jones TK, Prescott HC, Dickson RP, Nelson K, McSparron JI, Lagina M, Denstaedt SJ, Admon AJ, Patel BK, Wolfe KS, Hite RD, Hudock KM, Bastarache JA, Koyama T, Kerchberger VE, Ely EW, Jackson JC, Sinha P, Mudd PA, Kraft BD, Fremont RD, Singh R, Aggarwal NR, Jolley SE, Burnham EL, Mantelli RA, Janssen WJ, Moore CM, Douglas IS, Peterson R, Peltan ID, Barkauskas CE, Pratt EH, Harris ES, Scharfstein DO, Needham DM, Sahetya SK, Parker AM, Iwashyna TJ, Shenderov K, Matthay MA, Alipanah-Lechner N, Magee L, Shwartzman T, Lin C, Weingart MF, Langelier CR, Chao O, Hendrickson CM, Kornblith LZ, Chak S, Bardillon K, Rodriguez KH, Rogers AJ, Moore AR, Levitt JE, Vojnik R, Perez C, Lindsell CJ, Shotwell MS, Blette BS, Imhoff BW, Rice TW, Rhoads JP, Womack KN, Merkel AR, Ahmad LN, Zhao X, Grandon IE, Gong MN for the APS Consortium: The ARDS, Pneumonia, and Sepsis (APS) Consortium: Rationale, Design, and Feasibility of a National Platform for Phenotyping Critical Illness Syndromes. Chest 2026 Notes: in press.
Trevor McCutcheon, Justin Desprebiteres, Amber Erich, Kate Deppen, Stefanie Darnley, Danielle Sandsmark, Ramon Diaz-Arrastia, Vidyulata Kamath, Jeffrey Ware, Andrea L.C. Schneider, Alexa Walter: Subjective and Objective Findings of Anosmia are Discordant and Persist for 6 months in Hospitalized Individuals with Traumatic Brain Injury. American Academy of Neurology Annual Meeting 2026.
Nuala J. Meyer Rogan Magee John P. Reilly Ali Kamal James C. Jackson E Wesley Ely Jillian Rhoads Matthew Shotwell Samuel M. Brown Carolyn S. Calfee Michael O. Harhay Robert Hyzy Marc Moss Lorraine B. Ware Wesley H. Self Michelle N. Gong Dale M. Neeham Sarah J. Beesley Mihir R. Atreya Kathleen A. Stringer Pratik Sinha Angela J. Rogers Joseph A. Hippensteel Danielle K. Sandsmark : Plasma tau and neurofilament light chain, markers of neuronal injury, associate with delirium duration, survival, and subjective cognitive complaints in the ARDS, Pneumonia, and Sepsis Consortium. American Thoracic Society Annual Meeting 2026.
Weppner JL Gray J Kuehl D Sandsmark D Mirshahi N Diaz-Arrastia R Rascovsky K Peacock F Van Meter TE: Differentiating Traumatic Brain Injury from Dementia in Older Adults Using BrainCheck: An Emergency Department Feasibility Study. Diagnostics 2026.
Moyer M Maloney-Wilensky E Tsang Y Boivin CC Kumar S Coghlan L Wu A Mendez J Hinkle J Murphy H Sandsmark DK: The characterization of patient with external ventricular drains who participated in a nurse-initiated early mobilization program in the neurological intensive care unit. J Neurosci Nurse 2026.
Thomas R Sandsmark DK et al: Associations of VEGF-A Levels with Traumatic Brain Injury Severity and Outcomes: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study (TRACK-TBI) Study Neurotrauma Reports 2026.
Sabrina Abbruzzese Ronit Patel Alexa E. Walter Cillian E. Lynch Danielle K. Sandsmark Douglas H. Smith Andrea L.C. Schneider Ramon Diaz-Arrastia: Proteomic changes of neurodegenerative and inflammatory plasma biomarkers following traumatic brain injury. Neurotrauma Reports 2026.
De Boer, Christopher Sandsmark, Danielle Pascual, Jose: Bedside neurologic monitoring Principles of Adult Surgical Critical Care. Springer Nature, 2025.