Matthew P Kirschen, MD, PhD, MSCE
Associate Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania and the Children's Hospital of Philadelphia
Director, Pediatric Neurocritical Care Fellowship Program, Children's Hospital of Philadelphia
Director, Pediatric Neurocritical Care, Children's Hospital of Philadelphia
Department: Anesthesiology and Critical Care
Contact information
Children's Hospital of Philadelphia
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104-4399
Department of Anesthesiology and Critical Care Medicine
3401 Civic Center Boulevard
Philadelphia, PA 19104-4399
Office: 215-590-7430
Email:
kirschenm@chop.edu
kirschenm@chop.edu
Education:
BS (Neuroscience)
Brandeis University , 2000.
PhD (Neuroscience)
Stanford University School of Medicine , 2006.
MD (Medicine)
Stanford University School of Medicine, 2007.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2025.
BS (Neuroscience)
Brandeis University , 2000.
PhD (Neuroscience)
Stanford University School of Medicine , 2006.
MD (Medicine)
Stanford University School of Medicine, 2007.
MSCE (Clinical Epidemiology)
University of Pennsylvania, 2025.
Post-Graduate Training
Resident in Pediatrics, Lucile Packard Children’s Hospital, Stanford University School of Medicine, Palo Alto, CA, 2007-2009.
Fellow in Child Neurology, Children’s Hospital of Philadelphia, Philadelphia, PA, 2009-2012.
Fellow in Pediatric Critical Care Medicine, Children’s Hospital of Philadelphia, Philadelphia, PA, 2012-2015.
Resident in Pediatrics, Lucile Packard Children’s Hospital, Stanford University School of Medicine, Palo Alto, CA, 2007-2009.
Fellow in Child Neurology, Children’s Hospital of Philadelphia, Philadelphia, PA, 2009-2012.
Fellow in Pediatric Critical Care Medicine, Children’s Hospital of Philadelphia, Philadelphia, PA, 2012-2015.
Certifications
Pediatric Advanced Life Support , 2007.
American Board of Neurology and Psychiatry (Child Neurology) , 2012.
Advanced Cardiac Life Support , 2012.
Advanced Trauma Life Support , 2012.
American Board of Pediatrics, 2013.
Pediatric Advanced Life Support Instructor, 2014.
American Board of Pediatrics (Critical Care Medicine), 2016.
Emergency Neurological Life Support (ENLS), 2016.
Basic Life Support Instructor re-certification, 2018.
Permanent linkPediatric Advanced Life Support , 2007.
American Board of Neurology and Psychiatry (Child Neurology) , 2012.
Advanced Cardiac Life Support , 2012.
Advanced Trauma Life Support , 2012.
American Board of Pediatrics, 2013.
Pediatric Advanced Life Support Instructor, 2014.
American Board of Pediatrics (Critical Care Medicine), 2016.
Emergency Neurological Life Support (ENLS), 2016.
Basic Life Support Instructor re-certification, 2018.
Selected Publications
Silva LEV, Gaudio HA, Padmanabhan V, Forti RM, Shi L, Mason M, Sueishi T, Kirschen MP, Baker WB, Kilbaugh TJ, Morgan RW, Tsui FR, Ko TS: Machine Learning-Based Return of Spontaneous Circulation Prediction During Cardiopulmonary Resuscitation in a Swine Model of Cardiac Arrest: Effect of Data Resolution and Multimodal Physiological Waveforms. Critical Care Medicine 54(2): 257–269, February 2026.Loaec M, Vossough A, Francoeur C, Graham K, Morgan RW, Topjian AA, Kirschen MP: Spinal cord ischemia following pediatric cardiac arrest: An unexplored complication of hypoxic ischemic injury. Journal of Clinical Neuroscience 147: 111916, February 2026 Notes: Online ahead of print.
Silva LEV, Balcarcel D, Ko TS, Morgan RW, Berg RA, Topjian A, Tsui FR, Kirschen MP: Prediction of neurological outcome after pediatric cardiac arrest using heart rate variability and machine learning. Resuscitation 219: 110961, February 2026 Notes: Epub 2026 Jan 5.
Steinberg A, Annoni F, Hayashida K, Hutton J, Kirschen MP, Morgan RW: Wolf Creek XVIII Part 8: Wolf Creek Innovator in Cardiac Arrest and Resuscitation Science Award. Resuscitation Plus 28: 101230, January 2026.
Andrist E, Kiragu A, Kirschen MP, Agarwal K, Pope TM, Vercler CJ, Saylor KM, Flori HR, Carroll CL; Society of Critical Care Medicine Contestation of Pediatric Brain Death Task Force: Brain Death Contestation: A Scoping Review of Its Incidence and Management. Critical Care Medicine 54(1): 154–162, January 2026 Notes: Epub 2025 Nov 27.
Mazzio EL, Catenaccio E, Liu R, Vossough A, Abend NS, Alcamo A, Huh JW, Lang SS, Berg RA, Topjian AA, Press C, Kirschen MP: Association of EEG Response to Hypertonic Saline and Neurologic Outcomes in Pediatric Acute Brain Injury. Neurocritical Care January 2026 Notes: Online ahead of print.
Ullman NL, Reeder RW, Topjian A, Morgan RW, Berg RA, Nadkarni VM, Palmer CA, Sutton RM, Press CA, Kirschen MP; ICU-RESUS, CPCCRN Investigators: Severe intracranial hemorrhage or ischemia associated with unfavorable outcomes after pediatric in-hospital cardiac arrest. Resuscitation 218: 110886, January 2026 Notes: Epub 2025 Nov 7.
Kirschen MA, Topjian A, Berg R: Author response: NIRS illuminates, but MAPopt should guide post-cardiac arrest care. Resuscitation 217: 110849, December 2025.
Montag E, Kirschen MP, Nathanson P, Morrison W, Fieldston E, Walter JK: Prioritization of Ethical Themes When Surrogates Object to Technology Removal After Brain Death Determination. Neurocritical Care 43(3): 727–735, December 2025 Notes: Epub 2025 Oct 8.
Andrist E, Kiragu A, Kirschen MP, Agarwal K, Pope TM, Vercler CJ, Saylor KM, Flori HR, Carroll CL; Society of Critical Care Medicine Contestation of Pediatric Brain Death Task Force: Brain Death Contestation: A Scoping Review of Occurrences and Management. Critical Care Medicine December 2025 Notes: Online ahead of print.