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Jeffrey Scott Phillips, PhD
4eResearch Assistant Professor of Neurology
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Department: Neurology
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Contact information
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B602 Richards
2f Penn Frontotemporal Degeneration Center
35 3700 Hamilton Walk
Philadelphia, PA 19104
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2f Penn Frontotemporal Degeneration Center
35 3700 Hamilton Walk
Philadelphia, PA 19104
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Graduate Group Affiliations
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- Neuroscience e
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Publications
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Links
b5 Search PubMed for articles
95 Penn Frontotemporal Degeneration Center profile
78 Github site for academic research projects
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b5 Search PubMed for articles
95 Penn Frontotemporal Degeneration Center profile
78 Github site for academic research projects
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Education:
21 7 BA 1d (English & Honors) c
2d Villanova University, 1997.
21 7 MS 21 (Cognitive psychology) c
31 University of Pittsburgh, 2009.
21 8 PhD 21 (Cognitive psychology) c
31 University of Pittsburgh, 2012.
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21 7 BA 1d (English & Honors) c
2d Villanova University, 1997.
21 7 MS 21 (Cognitive psychology) c
31 University of Pittsburgh, 2009.
21 8 PhD 21 (Cognitive psychology) c
31 University of Pittsburgh, 2012.
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Post-Graduate Training
24 a6 Postdoctoral fellow in neuroimaging, Vanderbilt Memory & Alzheimer's Center in the Department of Neurology for Vanderbilt University, TN, 2012-2013.
24 da Postdoctoral fellow in neurodegenerative disease, Penn Frontotemporal Degeneration Center for the Department of Neurology at the Perelman School of Medicine, University of Pennsylvania, PA, 2013-2019.
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Permanent link24 a6 Postdoctoral fellow in neuroimaging, Vanderbilt Memory & Alzheimer's Center in the Department of Neurology for Vanderbilt University, TN, 2012-2013.
24 da Postdoctoral fellow in neurodegenerative disease, Penn Frontotemporal Degeneration Center for the Department of Neurology at the Perelman School of Medicine, University of Pennsylvania, PA, 2013-2019.
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1f Frontotemporal dementia
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28 Magnetic resonance imaging (MRI)
3b Positron emission tomography (PET): amyloid and tau
22 Computational neuroimaging
2a Statistical programming (R, Python)
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Description of Research Expertise
2d Atypical Alzheimer's disease1f Frontotemporal dementia
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28 Magnetic resonance imaging (MRI)
3b Positron emission tomography (PET): amyloid and tau
22 Computational neuroimaging
2a Statistical programming (R, Python)
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197 McKinstry, D., Shi, Z., Ramos-Rolón, A. P., Phillips, J., Das, S., Li, X., Hager, N. M., Pond, T., Volkow, N. D., Kranzler, H. R., Dubroff, J. G., Nasrallah, I. M., & Wiers, C. E.: Hippocampal volume and brain tau pathology in opioid use disorder: Associations with non-fatal opioid overdose. Addiction Neuroscience 19: 100253, 2026.
279 Khandelwal, P., Duong, M. T., Levorse, L. M., A. Lim, S., Gauthier, N., Shenoy, V., Chung, E., Denning, A. E., Bahena, A., Trotman, W., Olm, C. A., Radhakrishnan, H., Ittyerah, R., Prabhakaran, K., Mizsei, G., Schuck, T., Robinson, J., Ohm, D. T., Phillips, J. S., ... Yushkevich, P. A.: VIOLET: Volumetric Image registration via Optimization and Learning for Efficient image Translation. Simulation and Synthesis in Medical Imaging V. Fernandez, D. Wiesner, L. Zuo, A. Casamitjana, & S. W. Remedios (eds.). Springer Nature Switzerland, Page: 84-96, 2026.
1a6 John L Robinson, Helen Cai, Nicholas J Loh, Omar Vazquez, Zahra Khodakaramimaghsoud, EunRan Suh, Vivianna M. Van Deerlin, Paul A. Yushkevich, Sharon X. Xie, Daniel T Ohm, David J Irwin, Jeffrey S Phillips, Edward B Lee.: Idiotypic-susceptible: a clinically relevant, neurofibrillary tangle subtype of Alzheimer's disease. Acta Neuropathologica 2026.
17b Daniel T. Ohm, Noah Capp, Philip Sabitini, Katheryn A.Q. Cousins, Jeffrey S. Phillips, Katya Rascovsky, David A. Wolk, Edward B. Lee, Corey T. McMillan, and David J. Irwin: Selectively vulnerable myeloarchitecture in behavioral variant frontotemporal dementia. Society for Neuroscience Annual Meeting 2025.
204 Watanabe, R., Papatriantafyllou, J. D., Maeda, K., Aguirre, G. K., Ando, M., Benoit, B., Grossman, M., Irwin, D. J., Kim, B., Massimo, L., McMillan, C. T., Papageorgiou, S. G., Phillips, J. S., Shiraishi, T., Sugihara, Y., Suh, E., Takashima, H., Toro, C., Van Deerlin, V. M., Nasrallah, I. M., and Lee, E. B.: Clinicopathological characterization of vacuolar tauopathy associated with VCP D395G. Alzheimer’s & Dementia 21(7): e70427, 2025.
1e3 Jesse S Cohen, Jeffrey Phillips, Sandhitsu R Das, Christopher A Olm, Hamsanandini Radhakrishnan, Emma Rhodes, Katheryn AQ Cousins, Sharon X Xie, Ilya M Nasrallah, Paul A Yushkevich, David A Wolk, Edward B Lee, Daniel Weintraub, David J Irwin, and Corey T McMillan: Posterior hippocampal sparing in Lewy body disorders with Alzheimer’s copathology: An in vivo MRI study. NeuroImage: Clinical 45(103714), 2025.
249 Jeffrey S. Phillips, Dahlia Kamel, Sevila Temirova, Marianthi Hareras, Chigozie Ibe, Quinn Hlava, Emily Xie, Katheryn A. Q. Cousins, Leslie M. Shaw, Sandhitsu R. Das, Jeffrey Maneval, Sara Manning, Christopher Brown, Katherine Lopez, Richard Keegan, Andrew Stephens, Corey T. McMillan, David J. Irwin, Liz Li, Ilya M. Nasrallah, and David A. Wolk: [18F]-PI-2620 uptake in the medial temporal lobes discriminates Alzheimer's disease from normal cognition and non-Alzheimer's dementias. Human Amyloid Imaging 2025.
16f Matyi, M. A., Radhakrishnan, H., Olm, C. A., Phillips, J. S., Cook, P. A., Rhodes, E., Gee, J. C., Irwin, D. J., McMillan, C. T., & Massimo, L.: Executive dysfunction relates to salience network desegregation in behavioral variant frontotemporal dementia. NeuroImage: Clinical 48: 103853, 2025.
21f Khandelwal, P., Duong, M. T., Levorse, L. M., Trotman, W., Bahena, A., Lim, S. A., Denning, A. E., Chung, E., Olm, C. A., Radhakrishnan, H., Ittyerah, R., Prabhakaran, K., Mizsei, G., Schuck, T., Emrani, S., Vizcarra, J. A., Robinson, J., Ohm, D. T., Phillips, J. S., … Yushkevich, P. A.: Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neuropathology patterns. bioRxiv Page: 2025.12.30.697140, 2025.
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Selected Publications
1df Briar Nowling, Hamsanandini Radhakrishnan, Christopher A. Sandolm, Christopher Brown, Sandhitsu Das, James C. Gee, Corey T. McMillan, Allison Snyder, Lauren Massimo, David A. Wolk, David J. Irwin, and Jeffrey S. Phillips: Developing a novel metric of atypicality in Alzheimer's disease regional volume changes. AD/PD 2026 International Conference on Alzheimer's and Parkinson's Diseases, Copenhagen. 2026.197 McKinstry, D., Shi, Z., Ramos-Rolón, A. P., Phillips, J., Das, S., Li, X., Hager, N. M., Pond, T., Volkow, N. D., Kranzler, H. R., Dubroff, J. G., Nasrallah, I. M., & Wiers, C. E.: Hippocampal volume and brain tau pathology in opioid use disorder: Associations with non-fatal opioid overdose. Addiction Neuroscience 19: 100253, 2026.
279 Khandelwal, P., Duong, M. T., Levorse, L. M., A. Lim, S., Gauthier, N., Shenoy, V., Chung, E., Denning, A. E., Bahena, A., Trotman, W., Olm, C. A., Radhakrishnan, H., Ittyerah, R., Prabhakaran, K., Mizsei, G., Schuck, T., Robinson, J., Ohm, D. T., Phillips, J. S., ... Yushkevich, P. A.: VIOLET: Volumetric Image registration via Optimization and Learning for Efficient image Translation. Simulation and Synthesis in Medical Imaging V. Fernandez, D. Wiesner, L. Zuo, A. Casamitjana, & S. W. Remedios (eds.). Springer Nature Switzerland, Page: 84-96, 2026.
1a6 John L Robinson, Helen Cai, Nicholas J Loh, Omar Vazquez, Zahra Khodakaramimaghsoud, EunRan Suh, Vivianna M. Van Deerlin, Paul A. Yushkevich, Sharon X. Xie, Daniel T Ohm, David J Irwin, Jeffrey S Phillips, Edward B Lee.: Idiotypic-susceptible: a clinically relevant, neurofibrillary tangle subtype of Alzheimer's disease. Acta Neuropathologica 2026.
17b Daniel T. Ohm, Noah Capp, Philip Sabitini, Katheryn A.Q. Cousins, Jeffrey S. Phillips, Katya Rascovsky, David A. Wolk, Edward B. Lee, Corey T. McMillan, and David J. Irwin: Selectively vulnerable myeloarchitecture in behavioral variant frontotemporal dementia. Society for Neuroscience Annual Meeting 2025.
204 Watanabe, R., Papatriantafyllou, J. D., Maeda, K., Aguirre, G. K., Ando, M., Benoit, B., Grossman, M., Irwin, D. J., Kim, B., Massimo, L., McMillan, C. T., Papageorgiou, S. G., Phillips, J. S., Shiraishi, T., Sugihara, Y., Suh, E., Takashima, H., Toro, C., Van Deerlin, V. M., Nasrallah, I. M., and Lee, E. B.: Clinicopathological characterization of vacuolar tauopathy associated with VCP D395G. Alzheimer’s & Dementia 21(7): e70427, 2025.
1e3 Jesse S Cohen, Jeffrey Phillips, Sandhitsu R Das, Christopher A Olm, Hamsanandini Radhakrishnan, Emma Rhodes, Katheryn AQ Cousins, Sharon X Xie, Ilya M Nasrallah, Paul A Yushkevich, David A Wolk, Edward B Lee, Daniel Weintraub, David J Irwin, and Corey T McMillan: Posterior hippocampal sparing in Lewy body disorders with Alzheimer’s copathology: An in vivo MRI study. NeuroImage: Clinical 45(103714), 2025.
249 Jeffrey S. Phillips, Dahlia Kamel, Sevila Temirova, Marianthi Hareras, Chigozie Ibe, Quinn Hlava, Emily Xie, Katheryn A. Q. Cousins, Leslie M. Shaw, Sandhitsu R. Das, Jeffrey Maneval, Sara Manning, Christopher Brown, Katherine Lopez, Richard Keegan, Andrew Stephens, Corey T. McMillan, David J. Irwin, Liz Li, Ilya M. Nasrallah, and David A. Wolk: [18F]-PI-2620 uptake in the medial temporal lobes discriminates Alzheimer's disease from normal cognition and non-Alzheimer's dementias. Human Amyloid Imaging 2025.
16f Matyi, M. A., Radhakrishnan, H., Olm, C. A., Phillips, J. S., Cook, P. A., Rhodes, E., Gee, J. C., Irwin, D. J., McMillan, C. T., & Massimo, L.: Executive dysfunction relates to salience network desegregation in behavioral variant frontotemporal dementia. NeuroImage: Clinical 48: 103853, 2025.
21f Khandelwal, P., Duong, M. T., Levorse, L. M., Trotman, W., Bahena, A., Lim, S. A., Denning, A. E., Chung, E., Olm, C. A., Radhakrishnan, H., Ittyerah, R., Prabhakaran, K., Mizsei, G., Schuck, T., Emrani, S., Vizcarra, J. A., Robinson, J., Ohm, D. T., Phillips, J. S., … Yushkevich, P. A.: Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neuropathology patterns. bioRxiv Page: 2025.12.30.697140, 2025.
2c