Jeffrey Scott Phillips, PhD
Research Assistant Professor of Neurology
Department: Neurology
Contact information
B602 Richards
Penn Frontotemporal Degeneration Center
3700 Hamilton Walk
Philadelphia, PA 19104
Penn Frontotemporal Degeneration Center
3700 Hamilton Walk
Philadelphia, PA 19104
Graduate Group Affiliations
Publications
Links
Search PubMed for articles
Github site for academic research projects
Penn Frontotemporal Degeneration Center profile
Search PubMed for articles
Github site for academic research projects
Penn Frontotemporal Degeneration Center profile
Education
BA (English & Honors)
Villanova University, 1997.
MS (Cognitive psychology)
University of Pittsburgh, 2009.
PhD (Cognitive psychology)
University of Pittsburgh, 2012.
BA (English & Honors)
Villanova University, 1997.
MS (Cognitive psychology)
University of Pittsburgh, 2009.
PhD (Cognitive psychology)
University of Pittsburgh, 2012.
Post-Graduate Training
Postdoctoral fellow in neuroimaging, Vanderbilt Memory & Alzheimer's Center in the Department of Neurology for Vanderbilt University, TN, 2012-2013.
Postdoctoral fellow in neurodegenerative disease, Penn Frontotemporal Degeneration Center for the Department of Neurology at the Perelman School of Medicine, University of Pennsylvania, PA, 2013-2019.
Permanent linkPostdoctoral fellow in neuroimaging, Vanderbilt Memory & Alzheimer's Center in the Department of Neurology for Vanderbilt University, TN, 2012-2013.
Postdoctoral fellow in neurodegenerative disease, Penn Frontotemporal Degeneration Center for the Department of Neurology at the Perelman School of Medicine, University of Pennsylvania, PA, 2013-2019.
Description of Research Expertise
Atypical Alzheimer's diseaseFrontotemporal dementia
Magnetic resonance imaging (MRI)
Positron emission tomography (PET): amyloid and tau
Computational neuroimaging
Statistical programming (R, Python)
Selected Publications
Khandelwal, P., Duong, M. T., Levorse, L. M., Trotman, W., Bahena, A., Lim, S. A., Denning, A. E., Chung, E., Olm, C. A., Radhakrishnan, H., Ittyerah, R., Prabhakaran, K., Mizsei, G., Schuck, T., Emrani, S., Vizcarra, J. A., Robinson, J., Ohm, D. T., Phillips, J. S., … Yushkevich, P. A.: Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neurodegenerative pathologies. Alzheimer's & Dementia 22(7): e71649, 2026.Matyi, M. A., Pecsok, M. K., Olm, C. A., Radhakrishnan, H., Dratch, L., Van Deerlin, V. M., Rhodes, E., Phillips, J. S., Cook, P. A., Gee, J. C., Irwin, D. J., McMillan, C. T., Roalf, D., & Massimo, L.: Spatial covariance of mGluR5 density and structural degeneration in behavioral variant frontotemporal degeneration. Imaging Neuroscience 2026.
Briar Nowling, Hamsanandini Radhakrishnan, Christopher A. Sandolm, Christopher Brown, Sandhitsu Das, James C. Gee, Corey T. McMillan, Allison Snyder, Lauren Massimo, David A. Wolk, David J. Irwin, and Jeffrey S. Phillips: Developing a novel metric of atypicality in Alzheimer's disease regional volume changes. AD/PD 2026 International Conference on Alzheimer's and Parkinson's Diseases, Copenhagen. 2026.
Khandelwal, P., Duong, M. T., Levorse, L. M., A. Lim, S., Gauthier, N., Shenoy, V., Chung, E., Denning, A. E., Bahena, A., Trotman, W., Olm, C. A., Radhakrishnan, H., Ittyerah, R., Prabhakaran, K., Mizsei, G., Schuck, T., Robinson, J., Ohm, D. T., Phillips, J. S., ... Yushkevich, P. A.: VIOLET: Volumetric Image registration via Optimization and Learning for Efficient image Translation. Simulation and Synthesis in Medical Imaging V. Fernandez, D. Wiesner, L. Zuo, A. Casamitjana, & S. W. Remedios (eds.). Springer Nature Switzerland, Page: 84-96, 2026.
John L Robinson, Helen Cai, Nicholas J Loh, Omar Vazquez, Zahra Khodakaramimaghsoud, EunRan Suh, Vivianna M. Van Deerlin, Paul A. Yushkevich, Sharon X. Xie, Daniel T Ohm, David J Irwin, Jeffrey S Phillips, Edward B Lee.: Idiotypic-susceptible: a clinically relevant, neurofibrillary tangle subtype of Alzheimer's disease. Acta Neuropathologica 2026.
McKinstry, D., Shi, Z., Ramos-Rolón, A. P., Phillips, J., Das, S., Li, X., Hager, N. M., Pond, T., Volkow, N. D., Kranzler, H. R., Dubroff, J. G., Nasrallah, I. M., & Wiers, C. E.: Hippocampal volume and brain tau pathology in opioid use disorder: Associations with non-fatal opioid overdose. Addiction Neuroscience 19: 100253, 2026.
Khandelwal, P., Duong, M. T., Levorse, L. M., Trotman, W., Bahena, A., Lim, S. A., Denning, A. E., Chung, E., Olm, C. A., Radhakrishnan, H., Ittyerah, R., Prabhakaran, K., Mizsei, G., Schuck, T., Emrani, S., Vizcarra, J. A., Robinson, J., Ohm, D. T., Phillips, J. S., … Yushkevich, P. A.: Postmortem brain MRI reveals differential associations of subcortical and limbic volumes with cortical thinning and neuropathology patterns. bioRxiv Page: 2025.12.30.697140, 2025.
Daniel T. Ohm, Noah Capp, Philip Sabitini, Katheryn A.Q. Cousins, Jeffrey S. Phillips, Katya Rascovsky, David A. Wolk, Edward B. Lee, Corey T. McMillan, and David J. Irwin: Selectively vulnerable myeloarchitecture in behavioral variant frontotemporal dementia. Society for Neuroscience Annual Meeting 2025.
Matyi, M. A., Radhakrishnan, H., Olm, C. A., Phillips, J. S., Cook, P. A., Rhodes, E., Gee, J. C., Irwin, D. J., McMillan, C. T., & Massimo, L.: Executive dysfunction relates to salience network desegregation in behavioral variant frontotemporal dementia. NeuroImage: Clinical 48: 103853, 2025.
Shen, T., Vogel, J. W., Van Deerlin, V. M., Suh, E., Dratch, L., Phillips, J. S., Massimo, L., Lee, E. B., Irwin, D. J., & McMillan, C. T.: Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration. Molecular Degeneration 20(1): 17, 2025.