2 11 40 3d 3d 40 8 16 35 43 2b8 21 1a e 7d George T Kannarkat | Department of Neurology | Perelman School of Medicine at the University of Pennsylvania 62 4d 65 48 48 54 4e 52 5f 41 43 52 5b 7e 7a 88 59 55 4e 5f 57 4b 10 13 58 94 88 1e9 9 10e 3c 1f
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89 faculty photo 38

George T Kannarkat, MD, PhD

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Assistant Professor of Neurology at the Hospital of the University of Pennsylvania
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Department: Neurology
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46 Contact information
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3900 Woodland Avenue
Philadelphia, PA 19104-4551
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18 Publications
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13 Education:
21 7 BA 2b (Biology, International Studies) c
2a Baylor University, 2009.
21 8 PhD c
3c Emory University School of Medicine, 2016.
21 7 MD c
3c Emory University School of Medicine, 2017.
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1f Post-Graduate Training
24 48 Intern in Medicine, Johns Hopkins Hospital, 2017-2018.
24 4b Resident in Neurology, Johns Hopkins Hospital, 2018-2021.
24 6f Fellow in Movement Disorders, Pennsylvania Hospital and Veterans Affairs Hospital, 2021-2023.
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17 Certifications
28 3e Fundamentals of Critical Care Support, 2017.
28 3c Emergency Neurological Life Support, 2018.
28 4d Unified Dyskinesia Rating Scale Training Certificate, 2021.
28 51 American Board of Psychiatry and Neurology – Neurology, 2021.
28 58 Unified Parkinson’s Disease Rating Scale Training Certificate, 2021.
28 3d Advanced Care and Basic Life Support, 2022.
28 53 The Essential Tremor Rating Assessment Scale Certification, 2022.
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Description of Clinical Expertise

9e Movement disorders clinician who focuses on Parkinson's disease, REM-sleep behavior disorder, and those at-risk for neurodegenerative disease.
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Description of Research Expertise

bb Physician-scientist who is interested in mechanisms outside the brain (inflammation, protein misfolding, and environmental toxicants) that contribute to neurodegeneration.
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Selected Publications

149 George Kannarkat, Dimple Chouhan, D. Kacy Cullen, John Duda: Tissue-Engineered Nigrostriatal Pathways (TE-NSPs)Serve as a Novel Tool to Study the Cell-to-Cell Spread of Pathologic Alpha-Synuclein. American Neurological Association Annual Meeting 2025 2025.

d8 George Kannarkat: The Source and Pathogenic Potential of Blood-derived Alpha-Synuclein. American Academy of Neurology Annual Meeting 2025 2025.

18c George Kannarkat, Travis Unger, Robert Skrinak, Caroline Lewis, Kelvin Luk, Thomas Tropea, Daniel Weintraub, Alice Chen-Plotkin: Blood-Derived Alpha-Synuclein Strains in Lewy Body Diseases are Associated with Extracellular Vesicles and Induce Cellular Inclusions. American Neurological Association Annual Meeting 2025 2025.

101 Nathan Zhang, Andres Fernandez del Castillo, George Kannarkat: Establishing the Parkinson's Disease At-Risk Clinic (PD-ARC). American Neurological Association Annual Meeting 2025 2025.

17b Kannarkat GT, Zack R, Skrinak RT, Morley JF, Davila-Rivera R, Arezoumandan S, Dorfman K, Luk K, Wolk DA, Weintraub D, Tropea TF, Lee EB, Xie SX, Chandrasekaran G, Lee VM, Irwin D, Akhtar RS, Chen-Plotkin AS.: Blood α-Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies. Ann Neurol 2025.

130 Gilboa T, Ter-Ovanesyan D, Wang SC, Whiteman S, Kannarkat GT, Church GM, Chen-Plotkin AS, Walt DR.: Measurement of α-synuclein as protein cargo in plasma extracellular vesicles. Proc Natl Acad Sci U S A 121: e2408949121, Nov 2024.

190 Kannarkat GT, Zack R, Skrinak RT, Morley JF, Davila-Rivera R, Arezoumandan S, Dorfmann K, Luk K, Wolk DA, Weintraub D, Tropea TF, Lee EB, Xie SX, Chandrasekaran G, Lee VM, Irwin D, Akhtar RS, Chen-Plotkin AS.: α-Synuclein Conformations in Plasma Distinguish Parkinson's Disease from Dementia with Lewy Bodies. Res Sq Sep 2024.

c0 Kannarkat JT, Kannarkat GT, Jones LK Jr.: Neurologic Alternative Payment Models-Bridging the Gap. JAMA Neurol Jan 2024.

119 Tropea TF, Kannarkat GT, Shaw LM.: Early and Accurate Diagnosis of Parkinson’s Disease May Be Rooted in Seed Amplification Assays. Clinical Chemistry 69(11), Nov 2023 Notes: DOI: 10.1093/clinchem/hvad111.

ec Tropea TF, Kannarkat GT, Shaw LM.: Early and Accurate Diagnosis of Parkinson Disease May Be Rooted in Seed Amplification Assays. Clin Chem 69: 1209-1211, Nov 2023.

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26 Last updated: 11/10/2025
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