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Srdjan Joksimovic, PharmD, PhD

Research Assistant Professor of Neurology
Penn Research Associate, CHOP
Department: Neurology

Contact information
3615 Civic Center Blvd.
Abramson, Suite 409
Philadelphia, PA 19104-4319
PharmD (Pharmacy)
School of Pharmacy University of Belgrade, 2006.
PhD (Pharmacology)
School of Pharmacy University of Belgrade, 2013.
Post-Graduate Training
Postdoctoral fellow in Anesthesiology, School of Medicine University of Virginia, 2014-2016.
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Selected Publications

Joksimovic SM, Ghodsi SM, Heinsbroek JA, Orfila JE, Busquet N, Tesic V, Valdez R, Fine-Raquet B, Jevtovic-Todorovic V, Raol YH, Herson PS, Todorovic SM: CaV3.1 T-type calcium channels are important for spatial memory processing in the dorsal subiculum. Neuropharmacology. Elsevier Ltd. Dec 2022.

Joksimovic SM, Sampath D, Krishnan K, Covey DF, Jevtovic-Todorovic V, Raol YH, Todorovic SM.: Differential effects of the novel neurosteroid hypnotic (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile on electroencephalogram activity in male and female rats. Br J Anaesth 127(3): 435-446, Sept 2021.

Tat QL, Joksimovic SM, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V.: Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels. Cells 9: 2674, Dec 2020.

Raol YH, Joksimovic SM, Sampath D, Matter BA, Lam PM, Kompella UB, Todorovic SM, González MI.: The role of KCC2 in hyperexcitability of the neonatal brain. Neurosci Lett 738: 135324, Nov 2020.

Manzella FM, Joksimovic SM, Orfila JE, Fine BR, Dietz RM, Sampath D, Fiedler HK, Tesic V, Atluri N, Raol YH, Jevtovic-Todorovic V, Herson PS, Todorovic SM.: Neonatal Ketamine Alters High-Frequency Oscillations and Synaptic Plasticity in the Subiculum But Does not Affect Sleep Macrostructure in Adolescent Rats. Front Syst Neurosci 14: 26, May 2020.

Tesic V, Joksimovic SM, Quillinan N, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V.: Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABA(A) currents, but are not neurotoxic to the developing rat brain. Br J Anaesth 124(5): 603-613, May 2020.

Joksimovic SL, Joksimovic SM, Manzella FM, Asnake B, Orestes P, Raol YH, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM.: Novel neuroactive steroid with hypnotic and T-type calcium channel blocking properties exerts effective analgesia in a rodent model of post-surgical pain. Br J Pharmacol 177(8): 1735-1753, Apr 2020.

Diana P, Joksimovic SM, Faisant A, Jevtovic-Todorovic V.: Early exposure to general anesthesia impairs social and emotional development in rats. Mol Neurobiol 57(1): 41-50, Jan 2020.

Joksimovic SM, DiGruccio MR, Boscolo A, Jevtovic-Todorovic V, Todorovic SM.: The Role of Free Oxygen Radicals in Lasting Hyperexcitability of Rat Subicular Neurons After Exposure to General Anesthesia During Brain Development. Mol Neurobiol 57(1): 208-216, Jan 2020.

Joksimovic SM, Izumi Y, Joksimovic SL, Tesic V, Krishnan K, Asnake B, Jevtovic-Todorovic V, Covey DF, Zorumski CF, Todorovic SM.: Novel neurosteroid hypnotic blocks T-type calcium channel-dependent rebound burst firing and suppresses long-term potentiation in the rat subiculum. Br J Anaesth 122(5): 643-651, May 2019.

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Last updated: 01/14/2023
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