Samuel Alperin, MD
Assistant Professor of Clinical Neurology
Co-Chair of Section of Community Neurology, CHOP
Medical Director Inpatient Neurology Consult Service, CHOP
Department: Neurology
Education
BS
Cornell University, 2011.
MD
Hofstra Northwell Medical School, 2017.
BS
Cornell University, 2011.
MD
Hofstra Northwell Medical School, 2017.
Post-Graduate Training
Child Neurology Residency, Cincinnati Children's Hospital, 2017-2022.
Child Neurology Residency, Cincinnati Children's Hospital, 2017-2022.
Certifications
ABPN, 2022.
Permanent linkABPN, 2022.
Description of Clinical Expertise
Angelman Syndrome, Dup15q Syndrome, 22q11 Deletion Syndrome, 22q11 Duplication Syndrome, Autism, ADHDORCID identifier 
0000-0003-4703-2870
Selected Publications
Potter SN, Petzold C, Garbarini K, Forsythe AN, Jalazo E, Gable J, Zentz S, Okoniewski KC, Alperin S, Berry-Kravis E, Bird LM, Carson RP, de Wit MY, Heimer G, Le Pichon JB, Lindsey W, Lowden A, Makowski C, Marsh E, Myers KA, Nangia S, Nespeca M, Roche-Martínez A, Schleifer P, Sell E, Thibert R, Walleigh D, Moore A, Wheeler A. : Examining Epilepsy in Angelman Syndrome: Insights From Caregiver-Reported Data in the Linking Angelman and Dup15q Data for Expanded Research Database. Pediatric Neurology 182: 36-45, September 2026.Giuliana Caprara, Ashley Acevedo, Ashely Quinones, Samuel Alperin, Pamela Feliciano, Juhi Pandey, and the SPARK Consortium: A Glimpse into the Autism Phenotype within Rare Genetic Syndromes: An Exploration within the SPARK Study. Insar April 2026 Notes: Poster Presentation.
Ihnen SKZ, Alperin S, Capal JK, Cohen AL, Peters JM, Bebin EM, Northrup HA, Sahin M, Krueger DA; TACERN Study Group.: Accumulated seizure burden predicts neurodevelopmental outcome at 36 months of age in patients with tuberous sclerosis complex. Epilepsia 66(1): 117-133, January 2025.
Tyler M. Spivey, Donald L. Gilbert, Samuel Alperin: Neurological Conferences: A Comparison Study. Child Neurology Society 2023 October 2023 Notes: Poster Presentation.
Ihnen SK, Alperin S, Capal J, Horn P, Griffith M, Cohen A, Peters J, Warfield S, Kroeck M, Sahin M, Wu J, Bebin M, Northrup, Krueger D: Developmental Profiles in Early-Life Tuberous Sclerosis Complex (TSC). Child Neurology Society in Cincinnati October 2022 Notes: Oral Presentation.
Alperin S, Krueger DA, Franz DN, Agricola KD, Stires G, Horn PS, Capal JK.: Symptom rates and profile clustering in tuberous sclerosis complex-associated neuropsychiatric disorders (TAND). J Neurodev Disord 13(1): 60, December 2021.
Alperin, S., Krueger, D.A., & Capal J.K.: Tuberous Sclerosis-Associated Neuropsychiatric Disorders at Cincinnati Children’s Hospital. CNS-ICNA 2020 Meeting(Virtual) October 2020 Notes: Poster presentation.
Alperin, S., Clemens, N., Merritt, C., Statile A.M., & Mallon, D.: Implementation of a humanities in medicine curriculum for pediatric residents. Association of Pediatric Program Directors' Annual Spring Meeting, San Diego, CA March 2020 Notes: Poster Presentation.
Silverstein, M.J., Faraone, S.V., Alperin, S., Leon, T.L., Biederman, J., Spencer, T.J., & Adler L.A.: Validation of the expanded versions of the adult ADHD Self-Report Scale v1. 1 Symptom Checklist and the Adult ADHD Investigator Symptom Rating Scale. Journal of Attention Disorders 10(1): 1101-1110, August 2019.
Silverstein M.J., Alperin S., Hochstein Y., Adler L.A.: Moody Adults with ADHD. Moodiness in ADHD. Daviss W. (eds.). Springer, Cham, 12: 161–185, November 2018.