Harvey E. Smith - Faculty Biosketch

Harvey E. Smith, MD

Associate Professor of Orthopaedic Surgery at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center

Attending Orthopaedic Surgeon, Veteran Affairs Medical Center

Attending Orthopaedic Surgeon, Penn Presbyterian Medical Center

Attending Orthopaedic Surgeon, Hospital of the University of Pennsylvania

Attending Orthopaedic Surgeon, Pennsylvania Hospital

Department: Orthopaedic Surgery

Contact information

University of Pennsylvania School of Medicine
Department of Orthopaedic Surgery
3737 Market Street, 6th Floor
Philadelphia, PA 19104
Philadelphia, PA 19104

Office: 215-662-3340

Education:
A.B. (Chemistry & Physics)
Harvard University, 1997.
MD (Medicine)
Pennsylvania State University College of Medicine, 2002.

Post-Graduate Training
Research Training Fellowship for Medicial Students, Howard Hughes Medical Institute, 1999-2000.
Internship, Orthopaedic Surgery, Thomas Jefferson University, 2002-2003.
Resident, Orthopaedic Surgery, Thomas Jefferson University, 2003-2007.
Spine Surgery Basic Science Research and Clinical, Thomas Jefferson University and The Rothman Institute, 2007-2009.

Certifications
Diplomate, The American Board of Orthopaedic Surgery , 2012.

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Fainor M, Bazaz A, Smith HE, Gullbrand SE: Assessing Cell Therapy Retention And Survival Across A Spectrum Of Intervertebral Disc Degeneration In Rabbits. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2025.

Gullbrand SE, Kiapour A, Barrett C, Fainor M, Orozco BS, Hilliard R, Mauck RL, Hast MW, Schaer TP, Smith HE: Restoration of physiologic loading after engineered disc implantation mitigates immobilization-induced facet joint and paraspinal muscle degeneration. Acta Biomaterialia 192: 128-139, 2025.

Ongini, ED, Abdullah M, Engiles JB, Orozco BS, Moehl A, Peredo A, Mahindroo S, Hilliard R, Schaer TP, Mauck RL, Smith HE, Farshad M, Snedeker JG, Gullbrand SE: Annulus Repair Via Interpenetrated Non-woven Scaffold Supports Tissue Integration And Prevents Herniation. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2025.

Fainor M, Bazaz A, Mauck RL, Smith HE, Gullbrand SE: Controlled Delivery of Deferoxamine in a Subcutaneous Model of Semi-Orthotopic Bone Formation. Proceedings of the Annual Meeting of the Orthopaedeic Research Society 2025.

Ongini ED, Abdullah M, Engiles JB, Orozco BS, Moehl A, Peredo A, Mahindroo S, Hilliard R, Schaer TP, Mauck RL, Smith HE, Farshad M, Snedeker JG, Gullbrand Se: Annulus Fibrosus Repair via Interpenetration of a Non-Woven Scaffold Supports Tissue Integration and Prevents Re-Herniation. JOR Spine 2025.

Peredo AP, Tsinman TK, Bonnevie ED, Jiang X, Smith HE, Gullbrand SE, Dyment NA, Mauck RL: Developmental Morphogens Direct Human Induced Pluripotent Stem Cells Toward an Annulus Fibrosus-like Cell Phenotype. JOR Spine 7(1), 2024.

Burt KG, Barrett C, Schaer T, Smith HE, Mauck RL, Gullbrand S: Innervation And Inflammation Correlate With Structural And Mechanical Changes In A Large Animal Model Of Intervertebral Disc Degeneration. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2024.

Gullbrand SE, Kiapour A, Hast M, Orozco B, Fainor M, Godshall S, Hilliard R, Schaer T, Mauck RL, Smith HE: Mechanisms Of Facet Degeneration Adjacent To Engineered Discs Implanted With Plate Fixation. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2024.

Abdullah MS, Dehghani B, Engiles J, Barrett C, Burt K, Mauck RL, Smith HE, Schaer T, Gullbrand S: In Situ And In Vivo Mechanoactivation Of Anti-inflammatory Tension-activated Repair Patches. Proceedings of the Annual Meeting of the Orthopaedic Research Society 2024.

Gullbrand SE, Orozco BS, Fainor M, Meadows K, Hilliard R, Boyes M, Mahindroo S, Mauck RL, Elliott DM, Schaer TP, Smith HE: Intervertebral disc degeneration instigates vertebral endplate remodeling and facet joint pathology in a large animal model. European Cells and Materials 47: 125-41, 2024.