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Benjamin Anthony D'Souza, MD

Associate Professor of Clinical Medicine (Cardiovascular Medicine)
Department: Medicine

Contact information
Penn Presbyterian Medical Center
Hospital and Vascular Pavilion
51 N. 39th Street, 4th floor
Philadelphia, PA 19104
Office: 215-662-9000
Education:
B.S./B.A. (Biology/Honors Studies)
Villanova University , 2003.
MD (Medicine)
Jefferson Medical College of Thomas Jefferson University, 2007.
Post-Graduate Training
Intern, Internal Medicine/Pediatrics, Hospital of the University of Pennsylvania/The Children’s Hospital of Philadelphia, Philadelphia, PA, 2007-2008.
Resident, Internal Medicine/Pediatrics, Hospital of the University of Pennsylvania/The Children’s Hospital of Philadelphia, Philadelphia, PA, 2008-2011.
Fellow, Cardiovascular Diseases, Hospital of the University of Pennsylvania, Philadelphia, PA, 2011-2013.
Fellow, Cardiac Electrophysiology, Hospital of the University of Pennsylvania, Philadelphia, PA, 2013-2015.
Chief Fellow, Cardiovascular, Hospital of the University of Pennsylvania, 2013-2014.
Chief Fellow, Electrophysiology, Hospital of the University of Pennsylvania, 2014-2015.
Certifications
Diplomate, American Board of Internal Medicine, 2011.
Diplomate, American Board of Pediatrics, 2011.
Diplomate, American Board of Internal Medicine, Cardiovascular Disease, 2014.
Diplomate, American Board of Internal Medicine, Cardiac Electrophysiology, 2015.
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Selected Publications

Patel PJ, Gilge JL, D'Souza BA, Srivastava A, Sheik F, Hsaio S, Ravichandran AK; IDEAL‐HF researchers.: Periprocedural Risk Factors for Early Incident Acute Heart Failure After Catheter Ablation of Atrial Fibrillation: Findings From the CLAPHAF Study. J Cardiovasc Electrophysiol Jul 2025.

Oza SR, Hincapie D, Gupta M, Varley AL, Thorne C, Silverstein JR, Gabr M, Thosani AJ, Miranda-Arboleda AF, Osorio J, Velasco A, Jazayeri MA, Sackett MC, Costea A, Moretta A, Kuk R, Silva JM, D'Souza B, Belden W, Metzl MD, Quin M, Morris KE, Romero JE, Steiger NA, Sauer W, Zei PC.: Isoproterenol for Unmasking Dormant Conduction and Non-Pulmonary Vein Triggers During Atrial Fibrillation Ablation: Prospective Multicenter Study. J Cardiovasc Electrophysiol Jul 2025.

Reddy VY, Gerstenfeld EP, Schmidt B, Nair D, Natale A, Saliba W, Verma A, Sommer P, Metzner A, Turagam M, Weiner S, Champagne J, Garcio-Bolao I, Calkins H, Olson J, Issa Z, Winner M, Su W, Tomassoni G, Kim J, Hook B, Delurgio DB, Gibson DN, Daccarett M, Patel C, Bhalla K, Shehata M, Harding JD, Cheung JW, Raybuck JD, Roelke S, Schwartz T, Sutton BS, Mansour M; ADVANTAGE-AF Investigators.: Pulsed Field Ablation for Persistent Atrial Fibrillation: 1-Year Results of ADVANTAGE AF. J Am Coll Cardiol 85: 1664-1678, May 2025.

Wazni OM, Saliba WI, Nair DG, Marijon E, Schmidt B, Hounshell T, Ebelt H, Skurk C, Oza S, Patel C, Kanagasundram A, Sadhu A, Sundaram S, Osorio J, Mark G, Gupta M, DeLurgio DB, Olson J, Nielsen-Kudsk JE, Boersma LVA, Healey JS, Phillips KP, Asch FM, Wolski K, Roy K, Christen T, Sutton BS, Stein KM, Reddy VY; OPTION Trial Investigators.: Left Atrial Appendage Closure after Ablation for Atrial Fibrillation. N Engl J Med 392: 1277-1287, Apr 2025.

Zei PC, Hincapie D, Rodriguez-Taveras J, Osorio J, Alviz I, Miranda-Arboleda AF, Gabr M, Thorne C, Silverstein JR, Thosani AJ, Varley AL, Moreno F, Zapata DA, D'Souza B, Rajendra A, Oza S, Linda Justice RN, Baranowski A, Phan H, Velasco A, Te CC, Sackett MC, Singleton MJ, Magnano AR, Singh D, Kuk R, Steiger NA, Sauer WH, Romero JE.: Procedural and Clinical Outcomes of High-Frequency Low-Tidal Volume Ventilation Plus Rapid-Atrial Pacing in Paroxysmal Atrial Fibrillation Ablation. J Cardiovasc Electrophysiol 2025.

Mountantonakis SE, Gerstenfeld EP, Mansour M, Cuoco FA, Natale A, Patel C, Gibson DN, Halperin BD, Santangeli P, D'Souza B, Coleman KM, Richards E, Albrecht EM, Schneider CW, Sutton BS, Reddy VY.: Predictors of atrial fibrillation freedom postablation with the pentaspline pulsed field ablation catheter: Subanalysis of the ADVENT Study. Heart Rhythm 2025.

Gupta M, Thosani AJ, Thorne C, Osorio J, Jain R, Zei PC, Varley A, Singleton MJ, Oza S, Metzl M, D'Souza B, Magnano AR, Silverstein JR.: Real-world data analysis of trends in oral anticoagulation use in patients with atrial fibrillation following catheter ablation from a nationwide multicentric registry. Heart Rhythm 2025.

Claudio Schuger 1, Boyoung Joung 2, Kenji Ando 3, Lluís Mont 4, Pier D Lambiase 5, Gilles E O'Hara 6, John M Jennings 7, Derek Yung 8, Giuseppe Boriani 9, Jonathan P Piccini 10, Nicholas Wold 11, Kenneth M Stein 11, James P Daubert 10; APPRAISE ATP Investigators: Assessment of Antitachycardia Pacing in Primary Prevention Patients: The APPRAISE ATP Randomized Clinical Trial. JAMA 332: 1723-1731, November 2024.

Jose Osorio 1, Andres F Miranda-Arboleda 2, Alejandro Velasco 3, Allyson L Varley 4, Anil Rajendra 5, Gustavo X Morales 5, Carolina Hoyos 2, Carlos Matos 2, Christopher Thorne 4, Benjamin D'Souza 6, Joshua R Silverstein 7, Mark D Metzl 8, Shrinivas Hebsur 9, Alexandru I Costea 10, Steven Kang 11, Matthew Sellers 12, David Singh 13, Tariq Salam 14, Jose Nazari 8, Alex S Ro 8, Sean Mazer 15, Antonio Moretta 16, Saumil R Oza 17, Anthony R Magnano 18, Matthew Sackett 19, Jonathan Dukes 20, Parin Patel 21, Sandeep K Goyal 22, Todd Senn 23, David Newton 23, Jorge E Romero 2, Paul C Zei 24; REAL-AF Investigators: Real-world data of radiofrequency catheter ablation in paroxysmal atrial fibrillation: Short- and long-term clinical outcomes from the prospective multicenter REAL-AF Registry. Heart Rhythm November 2024.

Haran Yogasundaram 1, Muralidhar Reddy Papireddy 1, Saman Nazarian 1, Gustavo S Guandalini 1, Timothy M Markman 1, Robert D Schaller 1, Michael P Riley 1, David Lin 1, Sanjay Dixit 1, Benjamin D'Souza 2, Ramanan Kumareswaran 1, David J Callans 1, David S Frankel 1, Fermin C Garcia 1, Erica Zado 1, Rajat Deo 1, Andrew E Epstein 1, Gregory E Supple 1, Francis E Marchlinski 1, Matthew C Hyman 3: Long-term risk of right coronary artery injury after catheter ablation of cavotricuspid isthmus-dependent flutter. Heart Rhythm . September 2024.

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Last updated: 09/03/2025
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