Francis Edward Marchlinski - Faculty Biosketch

Francis Edward Marchlinski, MD

Richard T. and Angela Clark President's Distinguished Professor

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Department: Medicine

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46 Contact information
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The Pavilion
1d One Convention Avenue
1e 2 Pavilion - City Side
3f Electrophysiology Suite
Philadelphia, PA 19104-4283

30 Office: (215) 662-6005
34 Fax: (215) 662-2879
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18 Publications
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26 Search PubMed for articles c

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Links
df Search PubMed for articles
d8 2020 Peer Reviewed Original research publications
8e Penn Health Profile
83 Cardiovascular Division Faculty
d7 2021 peer reviewed original research publications
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13 Education:
21 9 B.S. 2a (Premedicine, Magna Cum Laude ) c
45 Pennsylvania State University, State College, 1973.
21 9 M.D. c
46 University of Pennsylvania School of Medicine, 1976.
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1f Post-Graduate Training
24 5c Intern in Medicine, Hospital of the University of Pennsylvania, 1976-1977.
24 5e Resident in Medicine, Hospital of the University of Pennsylvania, 1977-1979.
24 71 Research Fellow in Cardiology/Electrophysiology, Hospital of the University of PA. , 1979-1980.
24 5e Fellow in Cardiology, Hospital of the University of Pennsylvania, 1980-1982.
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17 Certifications
28 3e Board of Medical Examiners (Diplomat), 1977.
28 3c American Board of Internal Medicine, 1979.
28 56 Cardiovascular Diseases - American Board of Internal Medicine, 1981.
28 50 Electrophysiology - American Board of Internal Medicine, 1992.
28 50 Electrophysiology - American Board of Internal Medicine, 2002.
28 50 Electrophysiology - American Board of Internal Medicine, 2012.
28 50 Electrophysiology- American Board of Internal Medicine , 2022.
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b6 > Perelman School of Medicine > Faculty > Details a

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Description of Research Expertise

44 Electrophysiology of the human atria and ventricles
41 Mechanism of supraventricular and ventricular arrhythmias
58 Anatomic and electrophysiologic substrate of atrial and ventricular arrhythmias.
47 Catheter ablative therapy in atrial and ventricular arrhythmias
3f Device therapy in management of ventricular arrhythmias
3c Arrhythmogenic cardiomyopathy and cardiac arrhythmias
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Description of Clinical Expertise

59 Diagnosis and management of supraventricular and ventricular arrhythmias
56 Substrate mapping and catheter ablation of atrial and ventricular arrhythmias.
37 Pacemaker therapy in management of bradycardias
4d Implantable defibrillator therapy in treating ventricular arrhythmias
60 Management of atrial and ventricular arrhythmias in arrhythmogenic cardiomyopathy (ARVC)
4f Evaluation and treatment of genetically determined arrhythmia syndromes
36 Evaluation of patients with unexplained syncope
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Selected Publications

180 Shirai Y, Liang JJ, Santangeli P, Supple GE, Riley MP, Garcia FC, Lin D, Dixit S, Callans DJ, Marchlinski FE, Frankel DS, Schaller RD: Catheter Ablation of Premature Ventricular Complexes with Low Intraprocedural Burden Guided Exclusively by Pace-mapping. J Cardiovasc Electrophysio 30(11): 2326, November 2019.

159 Kodali S, Shirai Y, Muser D, Callans DJ, Marchlinski FE, Santangeli P: Ventricular Tachycardia in Nonischemic Cardiomyopathy:Anteroseptal Versus Inferolateral Origin Based On ICD Ventricular Electrogram Timing. J Cardiovasc Electrophysiol 30(11): 2334-2343, November 2019.

155 Maheshwari A, Shirai Y, Hyman MC, Arkles JS, Santangeli P, Schaller RD, Supple GE, Nazarian S, Lin D, Dixit S, Callans DJ, Marchlinski FE, Frankel DS: Septal Versus Mitral Isthmus Ablation for Treatment of Mitral Annular Flutter. JACC Clin Electrophysiol October 2019.

c9 Ustunkaya T, Desjardins B, Wedan R, Chahal CAA, Zimmerman SL, Saju N, Zahid S, Sharma A, Han Y, Trayanova N, Marchlinski FE, Calkins H, Tandri H, Nazarian S. a4 : Epicardial Conduction Speed, Electrogram Abnormality, and Computed Tomography Attenuation Associations in Arrhythmogenic Right Ventricular Cardiomyopathy 47 JACC Clin Electrophysio 5(10): 1158, Oct 2019.

9c Briceño DF, Liang JJ, Shirai Y Markman TM, Enriquez A, Lin A, Santangeli P, Riley MP, Schaller RD, Nazarian S, 7a Lin D, Kumareswaran R, Arkles JS, Hyman MC, Supple GE, Frankel DS, Garcia FC, Callans DJ, Marchlinski FE, e2 Dixit S.: Clinical and Electrophysiological Characteristics of Idiopathic Ventricular Arrhythmias Originating from the Slow Pathway Region Heart Rhythm 16(9): 142, September 2019.

10e Kuo L, Shirai Y, Muser D, Liang JJ, Castro SA, Santangeli P, Schaller RD, Supple GE, Lin D, Nazarian S, Dixit S, Callans DJ, Marchlinski FE, Frankel DS. : Comparison of the Arrhythmogenic Substrate Between Men and Women 21 with Nonischemic Cardiomyopathy 41 Heart Rhythm 16(9): 141, September 2019.

11b Kodali S, Shirai Y, Callans DJ, Zado ES, Marchlinski FE, Santangeli P: Usefulness of ICD Electrograms Analysis to Distinguish Endocardial Versus Epicardial Ventricular Tachycardia in Arrhythmogenic Right Ventricular Cardiomyopathy. f 51 J Cardiovasc Electrophysiol 30(9): 1526, September 2019.

169 Yang J, Brunnquell M, Liang JJ, Callans DJ, Garcia FC, Lin D, Frankel DS, Kay J, Marchlinski FE, Tzou W, Sauer WH, Liu B, Ruckdeschel ES, Collins K, Santangeli P, Nguyen DT. : Long term Follow-up after Ventricular Tachycardia Ablation in Patients with Congenital Heart Disease. J Cardiovasc Electrophysiol 31 30(9): 1560, September 2019.

109 Zielonka B, Kim YY, Supple GE, Partington SL, Ruckdeschel ES, Marchlinski FE, Frankel DS: Improvement in Ventricular Function with Rhythm Control of Atrial Arrhythmias May Delay the Need for Atrioventricular Valve 68 Surgery in Adults with Congenital Heart Disease. Congenit Heart Dis August 2019.

174 Shirai Y, Liang JJ, Santangeli P, Supple GE, Riley MP, Garcia FC, Lin D, Dixit S, Callans DJ, Marchlinski FE, Frankel DS, Schaller RD : Catheter Ablation of Premature Ventricular Complexes with Low Intraprocedural Burden Guided Exclusively by Pace-mapping J Cardiovasc Electrophysiol August 2019.

237 Marrouche NF, Wazni O, McGann C, Greene T, Dean JM, Dagher L, Kholmovski KE, Mansour M, Marchlinski FE, Wilber D, Hendricks G, Mahnkopf C, Wells D, Jais P, Sanders P, Brachmann J, Bax JJ, Morrison-de Boer L, Deneke T, Calkins H, Sohns C, Akoum N: DECAAF-II investigators: Effect of MRI-guided fibrosis ablation vs conventional catheter ablation on atrial arrhythmia recurrence in patients with persistent A-fib: The DECAAF II Randomized Clinical Trial. JAMA 21;327(23): 2296-2305, June 2022.

1bb Arceluz MR, Liuba I, Tschabrunn CM, Frankel DS, Santangeli P, Supple GS, Schaller RD, Garcia FC, Callans DJ, Guandalini Gustavos S. Walsh K, Nazarian S, Zado ES, Marchlinski FE. : "Sinus Rhythm QRS Amplitude and Fractionation in Patients with Non-Ischemic Cardiomyopathy to Identify Ventricular Tachycardia Substrate and Location" Heart Rhythm 19(2): 187-194, Feb 2022.

251 Thind M, Arceluz MR, Lucena-Padros I, Kubala M, Mirwais M, Bode W, Cerantola M, Sugrue A, Van Niekerk C, Vigdor A, Patel NA, AlSalem AB, Zado ES, Kumareswaran R, Lin D, Arkles JS, Garcia FC, Guandalini GS, Markman TM, Riley MP, Deo R, Schaller RD, Nazarian S, Dixit S, Epstein AE, Supple GE, Frankel DS, Tschabrunn CM, Santangeli P, Callans DJ, Hyman MC, Marchlinski FE: Identifying Origin of Nonpulmonary Vein Triggers Using 2 Stationary Linear Decapolar Catheters: A Novel Algorithm. JACC Clin Electrophysiol Nov 2023.

208 marrouche NF, Wazni O, McGann C, Greene T, Dean JM, Dagher L, Kholmovski E, Mansour M, Marchlinski F, Wilber D, Hindricks G, Mahnkopf C, Wells D, Jais P, Sanders P, Brachmann J, Bax JJ, Morrison-de Boer L, Deneke T, Calkins H, Sohns C, Akoum N;: Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent A-Fib: The DECAAF II. Randomized Clinical Trial. J JAMA june 2022.

1d9 Thind M, Oraii A, Chaumont C, Arceluz MR, Sekigawa M, Yogasundaram H, Sugrue A, Mirwais M, AlSalem AB, Zado ES, Guandalini GS, Markman TM, Deo R, Schaller RD, Dixit S, Epstein AE, Supple GE, Tschabrunn CM, Santangeli P, Callans DJ, Hyman MC, Nazarian S, Frankel DS, Marchlinski FE: Predictors of Non-Pulmonary vein triggers for atrial fibrillation: A clinical risk score. Heart Rhythm(24), Jan 2024.

10d Marchlinski FE, Oraii A, Muser D. : "Anticoagulation for atrial fibrillation in patients with intermediate stroke risk: is the grey zone becoming less grey?" Eur Heart J 45(1): 67-69, Jan 2024.

208 Chaumont C, Tschabrunn CM, Oraii A, Zado ES, Yogasundaram H, Sekigawa M, Markman T, Deo R, Dixit S, Epstein AE, Garcia FC, Lin D, Riley MP, Supple GE, Hyman MC, Nazarian S, Callans DJ, Anselme F, Frankel DS, Marchlinski FE. : Long-term freedom from ventricular arrhythmias in ARVC with endocardial only ablation: origin, and ablation outcomes of ventricular premature depolarizations initiating ventricular fibrillation. Heart Rhythm Jun 2024.

214 566. Boersma LV, Natale A, Haines D, DeLurgio D, Sood N, Marchlinski F, Calkins H, Hoyt RH, Sanders P, Irwin J, Packer D, Mittal S, Durrani S, DiBiase L, Sangrigoli R, Tada H, Sasano T, Tomita H, Yamane T, Kuck KH, Wazni O, Tarakji K, Cerkvenik J, van Bragt KA, Abeln BGS, Verma A.: Prevalence, timing, and impact of early recurrence of atrial tachyarrhythmias after pulsed field ablation: A secondary analysis of the PULSED AF trial. Heart Rhythm Jun 2024.

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26 Last updated: 10/26/2025
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