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Benedicte Lefebvre, MD

Assistant Professor of Clinical Medicine (Cardiovascular Medicine)
Department: Medicine

Contact information
11-134 South Pavilion
Perelman Center for Advanced Medicine
3400 Civic Center Blvd
Philadelphia, PA 19104
Education:
Pre-Univ (Health Sciences)
Collège Laflèche, Canada, 2007.
Pre-Med (Preparatory Medicine)
McGill University, Canada, 2008.
MD (Doctor of Medicine)
McGill University, Canada, 2012.
Post-Graduate Training
Residency, Internal Medicine, McGill University, Canada, 2012-2015.
Residency, Adult Cardiology, McGill University, Canada, 2015-2018.
Advanced Cardiac Imaging Fellowship, University of Pennsylvania, USA, 2018-2020.
Cardio-Oncology Fellowship, University of Pennsylvania, USA, 2020-2021.
Certifications
Licentiate of the Medical Council of Canada (LMCC) , 2013.
American Board Internal Medicine (ABIM), Internal Medicine, 2016.
Royal College of Medicine and Surgeons of Canada (FRCPC) Internal Medicine , 2016.
Royal College of Medicine and Surgeons of Canada (FRCPC), Adult Cardiology, 2018.
American Board Internal Medicine (ABIM), Cardiovascular Disease, 2018.
Cardiac Echocardiography, Level III (ACC/AHA/ASE, CSE) , 2019.
National Board of Echocardiography, 2019.
Certification Board of Cardiovascular Magnetic Resonance (CBCMR)-APCA, 2020.
Cardiac Magnetic Resonance, Level III (SCMR), 2020.
International Cardio-Oncology Society (IC-OS), 2021.
Permanent link
 
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Selected Publications

Lefebvre, Scherrer-Crosbie: Hematology: Basic Principles and Practice Chapter: Onco-cardiology: Focus on Cardiac Complications of Hematologic Treatments. Textbook 2026.

Lefebvre, Carver: ESC Textbook of Cardiovascular Medicine, 4th Edition. Textbook. Oxford University Press, 2026 Notes: Chapter underway.

Azin Vakilpour, Yulei Cao, Benedicte Lefebvre, Srinivas Denduluri, Amanda M Smith, Marielle Scherrer-Crosbie: CARDIOVASCULAR ADVERSE EVENTS AFTER BORTEZOMIB THERAPY IN PATIENTS WITH MULTIPLE MYELOMA: A LARGE REAL-WORLD DATA ANALYSIS. Journal of the American College of Cardiology April 2025.

Eva Berlin, Kyunga Ko, Lin Ma, Ian Messing, Casey Hollawell, Amanda M Smith, Neil K Taunk, Vivek Narayan, Jenica N Upshaw, Amy S Clark, Payal D Shah, Hayley Knollman, Saveri Bhattacharya, Daniel Koropeckyj-Cox, Jessica Wang, Nikhil Yegya-Raman, Ivy S Han, Benedicte Lefebvre, Tang Li, Nicholas S Wilcox, Wonyoung Jung, Jinbo Chen, Gary M Freedman, Bonnie Ky : Cardiac Effects of Modern Breast Radiation Therapy in Patients Receiving Systemic Cancer Therapy. JACC CardioOncology February 2025.

Takeshi Onoue, Andrew H Matthews, Azin Vakilpour, Yu Kang, Bénédicte Lefebvre, Amanda M Smith, Shannon R McCurdy, Michael G Fradley, Joseph Carver, Jesse Chittams, Marielle Scherrer-Crosbie: Cardiotoxicity of venetoclax in patients with acute myeloid leukemia: comparison with anthracyclines. Cardio-Oncology November 2024.

Yu Kang, Benedicte Lefebvre, Ingrid Marti Pamies, Saar I Gill, Abigail G Doucette, Srinivas Denduluri, Amanda M Smith, Shannon McCurdy, Selina Luger, Joseph Carver, Marielle Scherrer-Crosbie: Symptomatic Heart Failure and Clonal Hematopoiesis-Related Mutations in Patients With Acute Myeloid Leukemia. The American Journal of Cardiology September 2024.

Andy Y Wang, Peter M Rothwell, Jason Nelson, Jeffrey L Saver, Scott E Kasner, John Carroll, Jean-Louis Mas, Geneviève Derumeaux, Gilles Chatellier, Anthony J Furlan, Howard C Herrmann, Peter Jüni, Jong S Kim, Benjamin Koethe, Pil H Lee, Benedicte Lefebvre, Heinrich P Mattle, Bernhard Meier, Mark Reisman, Richard W Smalling, Lars Sondergaard, Jae-Kwan Song, Emanuele Di Angelantonio, Marco DiTullio, Mitchell S V Elkind, Shunichi Homma, Cheryl Jaigobin, Patrik Michel, Marie-Luise Mono, Krassen Nedeltchev, Federica Papetti, Joaquin Serena, Christian Weimar, Linxin Li, Sara Mazzucco, Louise E Silver, David van Klaveren, David E Thaler, David M Kent: Patent Foramen Ovale Closure in Older Patients With Stroke: Patient Selection for Trial Feasibility. Neurology May 2024.

Janane Maheswaran, Moezedin Javad Rafiee, Sydney Cordes, Benedicte Lefebvre, Michael Chetrit: Multimodality Imaging of Acute Myocarditis in Cytokine Release Syndrome (CRS) following CAR-T therapy. Canadian Journal of Cardiology April 2024.

Azin Vakilpour, Bénédicte Lefebvre, Catherine Lai, Marielle Scherrer-Crosbie : Heartbreaker: Detection and prevention of cardiotoxicity in hematological malignancies. Blood Reviews March 2024.

Kasey J Leger, Nora Robison, Hari K Narayan, Amanda M Smith, Tenaadam Tsega, Jade Chung, Amber Daniels, Zhen Chen, Virginia Englefield, Biniyam G Demissei, Benedicte Lefebvre, Gemma Morrow, Ilona Dizon, Robert B Gerbing, Reena Pabari, Kelly D Getz, Richard Aplenc, Jessica A Pollard, Eric J Chow, W H Wilson Tang, William L Border, Ritu Sachdeva, Todd A Alonzo, E Anders Kolb, Todd M Cooper, Bonnie Ky : Rationale and design of the Children's Oncology Group study AAML1831 integrated cardiac substudies in pediatric acute myeloid leukemia therapy. Frontiers in Cardiovascular Medicine December 2023.

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Last updated: 06/10/2025
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