Alejandro E. De feria alsina - Faculty Biosketch

Alejandro E. de Feria Alsina, MD

Assistant Professor of Clinical Medicine (Cardiovascular Medicine)

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Department: Medicine

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46 Contact information
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University of Pennsylvania, Room 11-134
3e 3400 Civic Center Boulevard
Philadelphia, Pa 19104

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13 Education:
21 7 BS c
2e University of Georgia, 2010.
21 7 MD 15 (Medicine) c
41 Vanderbilt University School of Medicine, 2015.
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1f Post-Graduate Training
24 6f Intern, Internal Medicine, Harvard Medical School, Brigham and Women’s Hospital, 2015-2016.
24 71 Resident, Internal Medicine, Harvard Medical School, Brigham and Women’s Hospital, 2016-2018.
24 75 Fellow, Cardiovascular Disease, Perelman School of Medicine, University of Pennsylvania, 2018-2021.
24 7f Fellow, Inherited Cardiovascular Disease, Perelman School of Medicine, University of Pennsylvania, 2021-2022.
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17 Certifications
28 3c American Board of Internal Medicine, 2018.
28 46 National Board of Echocardiography, Level III, 2020.
28 54 American Board of Internal Medicine, Cardiovascular Disease, 2021.
28 58 Society for Cardiovascular Magnetic Resonance Board Eligible, Cardiac MRI Level II 2 16 , 2022.
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b6 > Perelman School of Medicine > Faculty > Details a

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Description of Clinical Expertise

2b Hypertrophic Cardiomyopathy
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Description of Research Expertise

7f I am a sub investigator and echo reader for multiple clinical trials in genetic cardiomyopathy. These include:
6f 1)REDWOOD, SEQUOIA, and FOREST HCM (Cytokinetics study of aficamten in hypertrophic cardiomyopathy-HCM)
47 2)ODYSSEY HCM (Bristol Myers Squibb study of mavacamten in HCM)
4f 3)Natural History of BAG3 (Pfizer study in BAG3 dilated cardiomyopathy)
31 4)EDGWEISE (myosin modulator trial in HCM)
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Selected Publications

135 Reza N, Mahmud N, Austin MA, Duqueney E, Patel P, Boakye E, Hornsby N, de Feria A, Marzolf A, Owens AT. : Hypertension in Patients With Obstructive Hypertrophic Cardiomyopathy Treated With Mavacamten. JACC Heart Failure September 2025.

1de Thomas A Boyle, Nosheen Reza, Matthew Hyman, Gregory Supple, Vincent Y See, Amy Marzolf, Nicole Hornsby, Alejandro de Feria, Teresa Wang, Kenneth B Margulies, Anjali Tiku Owens, David S Frankel : Atrial Fibrillation in Patients Receiving Mavacamten for Obstructive Hypertrophic Cardiomyopathy: Real-World Incidence, Management, and Outcomes. Research Letter: JACC Clinical Electrophysiology February 2025.

ee Melissa A Austin, Alejandro de Feria, Nosheen Reza, Anjali Owens: Riding the Waves of Novel Therapies in Hypertrophic Cardiomyopathy. JACC Case Reports October 2024.

312 Niccolò Maurizi 1 2, Panagiotis Antiochos 2, Anjali Owens 3, Neal Lakdwala 4, Sara Saberi 5, Mark W Russell 6, Carlo Fumagalli 1 7, Ioannis Skalidis 2, Kimberly Y Lin 8, Ashwin S Nathan 3, Alejandro De Feria Alsina 3, Nosheen Reza 3, John C Stendahl 9, Dominic Abrams 10, Christopher Semsarian 11 12 13, Brian Clagget 14, Rachel Lampert 8, Matthew Wheeler 15, Victoria N Parikh 15, Euan Ashley 15, Michelle Michels 16, Joseph Rossano 8, Thomas D Ryan 17, Jodie Ingles 18, James Ware 19, Carolyn Y Ho 4, Adam S Helms 5, Sharlene M Day # 3, Iacopo Olivotto: Long-Term Outcomes After Septal Reduction Therapies in Obstructive Hypertrophic Cardiomyopathy: Insights From the SHARE Registry. Circulation October 2024.

196 Nosheen Reza, Anandkumar Dubey, Thomas Carattini, Amy Marzolf, Nicole Hornsby, Alejandro de Feria, Nadim Mahmud, Patricia Schuler, Anjali Tiku Owens: Real-World Experience and 36-Week Outcomes of Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy Treated With Mavacamten. JACC Heart Failure 12(6): 1123-1125, Jun 2024.

199 Melissa Austin, MD, Amy Marzolf, CRNP, Inhye Hwang, PhD, Joseph Puhl, BS, Alejandro de Feria, MD, Nosheen Reza, MD, Anjali Owens, MD : Dynamic Impact of Mavacamten on ECG Patterns of Left Ventricular Hypertrophy with Left Ventricular Strain. Accepted Case Report at Heart Rhythm Society meeting 2024 May 2024 Notes: Poster presentation.

28a Bart NK, Stroeks S, Parikh VN, Khan SS, Reza N, Olivotto I, Sinnette C, Owens AT, Fornaro A, Mestroni L, Taylor M, Helms A, Prasad S, Saberi S, Shores S, Verdonschot J, Sinagra G, Merlo M, Gigli M, Wilsbacher L, Heymans S, Wheeler M, Dal Ferro M, Paladino A, Day SM, De Feria A, Stevenson LW, Ho CY, Claggett B, Ware JS, Tayal U, Lakdawala NK on behalf of the SHaRe investigators: Sex and Gene Based Differences in Age Related Penetrance of Dilated and Arrhythmogenic Cardiomyopathy. AHA Scientific Sessions 2023, Philadelphia, Pennsylvania Nov 2023 Notes: Poster presentation.

198 Nosheen Reza1, Anandkumar Dubey, Thomas Carattini2, Amy Marzolf1, Nicole Hornsby1, Alejandro de Feria, Leticia Ferri, Anjali Owen: Real-World Patients With Obstructive Hypertrophic Cardiomyopathy Treated With Mavacamten: A US Single Center Experience. AHA Scientific Sessions 2023, Philadelphia, PA Nov 2023 Notes: Poster presentation.

10d Packard E, de Feria A, Peshin S, Reza N, Owens AT. : Contemporary Therapies and Future Directions in the Management of Hypertrophic Cardiomyopathy. Cardiology and Therapy 11(4): 491-507, Oct 2022.

14a Nosheen Reza, Alejandro de Feria, Jessica L Chowns, Lily Hoffman-Andrews, Laura Vann, Jessica Kim, Amy Marzolf, Anjali Tiku Owens: Cardiovascular Characteristics of Patients with Genetic Variation in Desmoplakin (DSP). Cardiogenetics 12(1): 24-36, Mar 2022.

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26 Last updated: 02/19/2026
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