Paul H. Edelstein - Faculty Biosketch

Paul H. Edelstein, MD

Emeritus Professor CE of Pathology and Laboratory Medicine

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Department: Pathology and Laboratory Medicine

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46 Contact information
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HUP - 4 Gates
15 3400 Spruce St
27 4283
Philadelphia, PA 19104

2c Office: 2156626651
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Email:
paul.edelstein@pennmedicine.upenn.edu

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18 Publications
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26 Search PubMed for articles c

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Links
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13 Education:
21 e no degree 1c (Chemistry major) c
45 San Jose State College, San Jose, California, 1969.
21 9 M.D. 15 (medicine) c
40 University of California at Los Angeles, 1973.
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1f Post-Graduate Training
24 56 Intern in Internal Medicine, Wadsworth VA Medical Center, 1973-1974.
24 58 Resident in Internal Medicine, Wadsworth VA Medical Center, 1974-1976.
24 58 Fellow in Infectious Diseases, Wadsworth VA Medical Center, 1976-1978.
24 51 Chief Medical Resident, Wadsworth VA Medical Center, 1977-1978.
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17 Certifications
28 44 National Board of Medical Examiners #131761, 1973.
28 59 American Board of Internal Medicine #055675 in Internal Medicine, 1976.
28 5b American Board of Internal Medicine #055675 in Infectious Diseases, 1978.
28 83 Diplomat of American Board of Medical Microbiology in Public Health and Medical and Molecular Microbiology, 1985.
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b6 > Perelman School of Medicine > Faculty > Details a

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Selected Publications

dc Edelstein, Paul H: Legionnaires' disease, Pontiac fever, and related illnesses. Feigin and Cherry's Textbook of Pediatric Infectious Diseases 2025.

151 Narayanan N, Mathers AJ, Wenzler E, Moore NM, Giske CG, Mendes RE, Edelstein PH.: Amoxicillin-Clavulanate Breakpoints Against Haemophilus influenzae: Rationale for Revision by the Clinical and Laboratory Standards Institute2. Clin Infect Dis 80: 481-482, Feb 2025.

1c7 Padmapriyadarsini C, Szumowski JD, Akbar N, Shanmugasundaram P, Jain A, Bathragiri M, Pattnaik M, Turuk J, Karunaianantham R, Balakrishnan S, Pati S, Kumar AKH, Rathore MK, Raja J, Naidu KR, Horn J, Whitworth L, Sewell R, Ramakrishnan L, Swaminathan S, Edelstein PH.: A Dose-Finding Study to Guide Use of Verapamil as an Adjunctive Therapy in Tuberculosis. Clin Pharmacol Ther 2024.

cb Behr MA, Edelstein PH, Ramakrishnan L.: Rethinking the burden of latent tuberculosis to reprioritize research. Nat Microbiol 2024.

14a Narayanan N, Mathers AJ, Wenzler E, Moore NM, Giske CG, Mendes RE, Edelstein PH.: Amoxicillin-Clavulanate Breakpoints Against Enterobacterales: Rationale for Revision by the Clinical and Laboratory Standards Institute. Clin Infect Dis 79: 516-523, Aug 2024.

130 Fan J, Hale VL, Lelieveld LT, Whitworth LJ, Busch-Nentwich EM, Troll M, Edelstein PH, Cox TM, Roca FJ, Aerts JMFG, Ramakrishnan L.: Gaucher disease protects against tuberculosis. Proc Natl Acad Sci U S A 120: e2217673120, Feb 2023.

17f Lake MA, Adams KN, Nie F, Fowler E, Verma AK, Dei S, Teodori E, Sherman DR, Edelstein PH, Spring DR, Troll M, Ramakrishnan L.: The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux and macrophage-induced rifampicin tolerance. Proc Natl Acad Sci U S A 120: e2215512120, Feb 2023.

185 Whitworth LJ, Troll R, Pagán AJ, Roca FJ, Edelstein PH, Troll M, Tobin DM, Phu NH, Bang ND, Thwaites GE, Thuong NTT, Sewell RF, Ramakrishnan L.: Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone. Proc Natl Acad Sci U S A 118: e2024852118, Mar 2021.

17f Whitworth L, Coxon J, van Laarhoven A, Thuong NTT, Dian S, Alisjahbana B, Ganiem AR, van Crevel R, Thwaites GE, Troll M, Edelstein PH, Sewell R, Ramakrishnan L.: A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival in tuberculous meningitis. Elife 10: e61722, Jan 2021.

bd Behr MA, Edelstein PH, Ramakrishnan L.: Is Mycobacterium tuberculosis infection life long? BMJ 367: l5770, Oct 2019.

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26 Last updated: 03/12/2025
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