Giacomo Maria Paganotti - Faculty Biosketch

Giacomo Maria Paganotti, PhD

Adjunct Associate Professor of Medicine (Infectious Diseases)

Director, Medical Education Laboratory, Botswana-UPenn Partnership Program, Gaborone, Botswana

Department: Medicine

Contact information

Botswana – UPenn Partnership
PO Box AC 157 ACH
Gaborone,

Office: 267 355-5375

Email:
paganottig@bup.org.bw

Education:
BS (Biological Sciences)
University of Rome, Tor Vergata, Italy, 1995.
MS
University of Rome, Tor Vergata, Italy, 1997.
PhD (Animal Biology)
University of Modena and Reggio, Emilia, Italy, 2002.

Post-Graduate Training
Researcher, University of Rome, Tor Vergata, Italy, 1994-1997.
Doctoral Fellow, University of Modena, Emilia, Italy , 1997-2002.
Biologist, University of Rome, Tor Vergata, Italy, 1997-1997.
Fellow, Institute Pasteur – Cenci Bolognetti Foundation, University of Rome “La Sapienza,” Italy, 2002-2004.
Return Fellow, Institute Pasteur – Cenci Bolognetti Foundation, University of Rome “La Sapienza,” Italy , 2005-2007.
Fellow, Department of Public Health and Infectious Diseases of the University of Rome “La Sapienza," Italy, 2008-2013.

Certifications
Epidemiology and prophylaxis of infectious diseases, Hospital Santo Spirito of Rome, Italy, 1999.

Permanent link

> Perelman School of Medicine > Faculty > Details

Description of Research Expertise

Plasmodium falciparum malaria, Plasmodium vivax malaria, antimalarial drug resistance, drug resistance selection, human genetics, susceptibility to infectious diseases, pharmacogenetics, ethnic groups, CYP450, Anopheles mosquitoes, PCR, DNA

Selected Publications

Masenga W, Paganotti GM, Seatla K, Gaseitsiwe S, Sichilongo K: A fast-screening dispersive liquid-liquid microextraction-gas chromatography-mass spectrometry method applied to the determination of efavirenz in human plasma samples Analytical and Bioanalytical Chemistry 413(25): 6401-12, October 2021.

Manake MG, Ramatlho P, Ntereke TD, Tawe L, Bango ZA, Quaye IK, Paganotti GM, Kasvosve I: Similar Ferroportin Q248H polymorphism prevalence in patients with Plasmodium falciparum malaria and control subjects in the low-endemic setting of Botswana. Clinica Chimica Acta 523(1): 77-80, September 2021.

Lo E, Russo G, Pestana K, Kepple D, Abagero BR, Dongho GBD, Gunalan K, Miller LH, Hamid MMA, Yewhalaw D, Paganotti GM: Contrasting epidemiology and genetic variation of Plasmodium vivax infecting Duffy-negative individuals across Africa. International Journal of Infectious Diseases 108(1): 63-71, July 2021.

Motshoge T, Haiyambo DH, Ayanful-Torgby R, Aleksenko L, Ntebela D, Malleret B, Rénia L, Peloewetse E, Paganotti GM, Quaye IK: Recent Molecular Assessment of Plasmodium vivax and Plasmodium falciparum Asymptomatic Infections in Botswana American Journal of Tropical Medicine and Hygiene 104(6): 2159–64, May 2021.

Maseng MJ, Tawe L, Thami PK, Seatla KK, Moyo S, Martinelli A, Kasvosve I, Novitsky V, Essex M, Russo G, Gaseitsiwe S, Paganotti GM: Association of CYP2B6 Genetic Variation with Efavirenz and Nevirapine Drug Resistance in HIV-1 Patients from Botswana. Pharmacogenomics and Personalized Medicine 14(1): 335-47, March 2021.

Abdelwhab OF, Elaagip A, Albsheer MM, Ahmed A, Paganotti GM, Abdel Hamid MM: Molecular and morphological identification of suspected Plasmodium vivax vectors in Central and Eastern Sudan. Malaria Journal 20(1): 132, March 2021.

Tawe L, Grover S, Zetola N, Robertson ES, Gaseitsiwe S, Moyo S, Kasvosve I, Paganotti GM, Narasimhamurthy M: Promoter Hypermethylation Analysis of Host Genes in Cervical Cancer Patients With and Without Human Immunodeficiency Virus in Botswana Frontiers in Oncology 11(1): 560296, February 2021.

Djeunang Dongho GB, Gunalan K, L'Episcopia M, Paganotti GM, Menegon M, Sangong RE, Georges BM, Fondop J, Severini C, Sobze MS, Miller LH, Russo G: Plasmodium vivax Infections Detected in a Large Number of Febrile Duffy-Negative Africans in Dschang, Cameroon American Journal of Tropical Medicine and Hygiene 104(3): 987-92, January 2021.

Kurenzvi L, Sebunya TK, Coetzee T, Paganotti GM, Teye MV: Prevalence of Cryptosporidium parvum, Giardia intestinali s and molecular characterization of group A rotavirus associated with diarrhea in children below five years old in Gaborone, Botswana Pan African Medical Journal 37(1): 159, October 2020.

Kgoroebutswe TK, Ramatlho P, Reeder S, Makate N, Paganotti GM: Distribution of Anopheles mosquito species, their vectorial role and profiling of knock-down resistance mutations in Botswana Parasitology Research 119(4): 1201-8, April 2020.