Joshua J. Brotman - Faculty Biosketch

Joshua J. Brotman, MD

Assistant Professor of Clinical Medicine (Pulmonary, Allergy and Critical Care)

Director, Inpatient Pulmonary Services, Hospital of the University of Pennsylvania

Director of Patient Safety, Department of Medicine, Perelman School of Medicine

Patient Safety Officer, Hospital of the University of Pennsylvania

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Department: Medicine

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46 Contact information
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University of Pennsylvania
35 Pulmonary, Allergy and Critical Care Medicine
4d 36th and Spruce Streets, Room 827 W. Gates
Philadelphia, PA 19104

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13 Education:
21 7 BS 14 (Biology) c
40 Truman State University, Kirksville, MO, 2003.
21 7 MD 15 (Medicine) c
45 Eastern Virginia Medical School, Norfolk, VA, 2013.
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1f Post-Graduate Training
24 b4 Resident in Internal Medicine, University of California, San Francisco, San Francisco, CA, Program in Residency Investigation Methods and Epidemiology, 2013-2016.
24 8a Fellow in Pulmonary and Critical Care Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 2017-2020.
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17 Certifications
28 3c American Board of Internal Medicine, 2016.
28 6e American Board of Internal Medicine, Subspecialty Certification in Pulmonary Diseases, 2019.
28 72 American Board of Internal Medicine, Subspecialty Certification in Critical Care Medicine, 2021.
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3 8d Permanent link
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b6 > Perelman School of Medicine > Faculty > Details a

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Description of Clinical Expertise

36 Chronic obstructive pulmonary disease
15 Bronchiolitis
d Asthma
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Selected Publications

1fa Liu H, Noguera-Ortega E, Dong X, Lee WD, Chang J, Aydin SA, Li Y, Shin Y, Shi X, Liousia M, Martinez MC, Brotman JJ, Kim S, Chen Z, Wang A, Ou Z, Paek J, Park JY, Liu A, Hu H, Xiao Z, Racca DM, Kim SJ, Worthen GS, Guo W, Puré E, Kang T, Rabinowitz JD, Wherry EJ, Moon EK, Albelda SM, Huh DD. : A tumor-on-a-chip for in vitro study of CAR-T cell immunotherapy in solid tumors Nature Biotechnology Epub ahead of print , October 2025.

1a8 Rohi Gheewala, MD, Yulei Cao, MD, Susan Landon, MD, Timothy Karutz, MBA, William D. Schweickert, MD, Janae K. Heath, MD, MSCE, Joshua J. Brotman, MD, Brian Jacob Anderson, MD, MS: Drivers of Prolonged Hospitalization for COPD Exacerbations: The Stakeholder Perspective. American Thoracic Society, San Francisco, CA May 2025 Notes: Poster presentation.

142 Tilsed CM, Brotman J, O'Brien S, Lee B, Moon E, Albelda SM.: Identification and characterization of tissue resident memory T cells in malignant pleural effusions associated with non-small cell lung cancer. Immunohorizons 9(6): vlaf013, April 2025.

aa Joshua J. Brotman, M.D., Jeffrey C. Thompson, M.D., M.S., Marina C. Martinez, Steven M. Albelda, M.D. and Edmund K. Moon, M.D. fc : Tissue Resident Memory CD8+ T cells are Present in Non-Small Cell Lung Carcinoma (NSCLC) Malignant Pleural Effusions (MPEs). American Thoracic Society International Conference 2021 May 2021 Notes: E-poster presentation.

f2 Brotman JJ, Kotloff RM. : Providing Outpatient Telehealth Services in the United States: Before and During Coronavirus Disease 2019 CHEST 159(4): 1548-1558, April 2021.

e1 Brotman JJ, Thompson JC, Martinez MC, Linette GP, Carreno BM, Tursi T, Jozefowski M, Albelda SM, Moo, EK: Tissue Resident Memory CD8+ T cells in Non-Small Cell Lung Carcinoma d4 (NSCLC) Malignant Pleural Effusions (MPEs) are Defined by the Cell Surface Marker CD69 Department of Medicine Research Day, University of Pennsylvania Jun 2020 Notes: Poster presentation.

191 Greenland JR, Wang P, Brotman JJ, Ahuja R, Chong TA, Kleinhenz ME, Leard LE, Golden JA, Hays SR, Kukreja J, Singer JP, Rajalingam R, Jones K, Laszik ZG, Trivedi NN, Greenland NY, Blanc PD: Gene signatures common to allograft rejection are associated with lymphocytic bronchitis. Clinical Transplantation 33(5): e13515, May 2019.

116 Dobrian AD, Hatcher MA, Brotman JJ, Galkina E, Moghadam PT, Pei H, Haynes BA, Nadler JL: STAT4 contributes to adipose tissue inflammation and atherosclerosis. Journal of Endocrinology 227: 13-24, Oct 2015.

13e Lieb DC, Brotman JJ, Hatcher MA, Aye MS, Cole BK, Haynes BA, Wohlgemuth SD, Fontana MA, Beydoun H, Nadler JL, Dobrian AD: Adipose tissue 12/15 lipoxygenase pathway in human obesity and diabetes. J Clin Endocrinol Metab 99(9): E1713-20, Sep 2014.

123 Judd NP, Winkler AE, Murillo-Sauca OJ, Brotman JJ, Law JH, Lewis Jr JS, Dunn GP, Bui JD, Sunwoo JB, Uppaluri R: ERK1/2 regulation of CD44 modulates oral cancer progressiveness. Cancer Research 72(1): 365-374, Jan 2012.

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26 Last updated: 02/04/2026
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