Meenakshi Bewtra, MD, PhD, MPH
Associate Professor of Medicine (Gastroenterology) at the Hospital of the University of Pennsylvania
Department: Medicine
Contact information
423 Guardian Drive
724 Blockley Hall
Philadelphia, PA 19104
724 Blockley Hall
Philadelphia, PA 19104
Office: 215-746-4922
Publications
Education
BSc
Yale University, New Haven, CT, 1998.
MD
University of Pennsylvania, Philadelphia, PA, 2003.
MPH
Harvard University School of Public Health, Boston, MA, 2003.
PhD (Epidemiology)
University of Pennsylvania, 2013.
BSc
Yale University, New Haven, CT, 1998.
MD
University of Pennsylvania, Philadelphia, PA, 2003.
MPH
Harvard University School of Public Health, Boston, MA, 2003.
PhD (Epidemiology)
University of Pennsylvania, 2013.
Links
Search PubMed for articles
Penn Medicine Inflammatory Bowel Disease Program
The Undergraduate Clinical Scholars Program is an epidemiology and biostatistics summer research enrichment program with research mentoring, with a goal of fostering strong research interests and durable mentoring relationships in human clinical research.
I am an active science, research and public health advocate.
University of Pennsylvania Perelman School of Medicine Center for Clinical Epidemiology and Biostatistics (CCEB)
Penn Medicine at Radnor
The IBD-Immunology Initiative (I3) is a prospective biobank enrolling all inflammatory bowel disease patients (IBD) at UPenn. The I3 has collaborators within Penn, nationally and internationally in academia, private foundations and industry.
Permanent linkSearch PubMed for articles
Penn Medicine Inflammatory Bowel Disease Program
The Undergraduate Clinical Scholars Program is an epidemiology and biostatistics summer research enrichment program with research mentoring, with a goal of fostering strong research interests and durable mentoring relationships in human clinical research.
I am an active science, research and public health advocate.
University of Pennsylvania Perelman School of Medicine Center for Clinical Epidemiology and Biostatistics (CCEB)
Penn Medicine at Radnor
The IBD-Immunology Initiative (I3) is a prospective biobank enrolling all inflammatory bowel disease patients (IBD) at UPenn. The I3 has collaborators within Penn, nationally and internationally in academia, private foundations and industry.
Selected Publications
Mehta SJ, Nguyen P, Brophy C, Reitz C, Snider CK, Bewtra M, Lewis JD.: Remote monitoring to improve engagement for patients with inflammatory bowel disease: a randomized clinical trial. Crohns Colitis 360 8: otag076, Jul 2026.Yang H, Dungan M, Madhu B, Beyries K, Wang X, Kilpatrick R, Chen B, Oh S, Berkowitz M, Smith D, Zhou C, Koralov SB, Axelrad J, Lengner CJ, Belle N, Bewtra M, Katona BW, Cadwell K: MAIT cell enrichment in Lynch syndrome is associated with immune surveillance and colorectal cancer risk. Gut May 2026.
Lewis JD, Bewtra M, Aberra FN, Weiss A.: Letter to the Editor. Am J Gastroenterol 121: e24-e25, Apr 2026.
Mayer AS, Xiao R, Grossman A, Bewtra M, George MD, Weiss PF.: Temporal Trends in and Associations With Nonsteroidal Anti-inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease. Arthritis Care Res (Hoboken) April 2026.
Mayer AS, Xiao R, Bewtra M, George MD, Weiss PF.: Safety of Prescription Nonsteroidal Anti-inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort. Arthritis Care Res (Hoboken) Apr 2026.
Tan T, Vincent M, Jain U, Deepak P; SPARC I. B. D. Investigators.: Metabolomic Profiling of Fecal Samples Reveals Distinct Signatures Associated with Disease Phenotypes and Locations in Crohn's Disease. Dig Dis Sci Mar 2026.
Mayer LS, Arnold J, Roettele F, Reuter N, Pattekar A, Ohtani T, Ribeiro MM, Siwicki R, Bruder K, Obwegs D, Stahl E, Buechel S, Roehlen N, Kolter J, Mansoori Moghadam Z, Alaswad A, Zhumalidova Z, Li G, Liu X, Li Y, Singh A, Villacorta Hidalgo J, Paraskevopoulou MD, Yajnik V, Juarez J, Ren Y, Li H, Wherry EJ, Lewis JD, Wu GD, Bewtra M, Tomov VT, Thimme R, Bengsch B, Hasselblatt P, Picelli S, Hofmann M, Sagar.: Single-cell profiling reveals diverse γδ T cell subsets in ulcerative colitis. Sci Immunol 11: eadx8474, Feb 2026.
Karakasheva TA, Martinez CM, Zhou Y, Qui J, Chen XE, Soto GE, Nettleford SK, Hix OT, Roach DM, Laguerta AM, Thadi A, Edwards RM, Aleynick D, Weinbrom S, Borodyanskaya E, Pickering OH, Fulton M, Chen CH, Peterson IV, Hagen EB, Yannuzzi IP, Haider Z, Cramer Z, Conrad MA, Li N, Bewtra M, Uzun Y, Tan K, Kelsen JR, Minn AJ, Lengner CJ, Hamilton KE.: An Epigenetic Basis for Sustained Inflammatory Epithelial Progenitor Cell States in Crohn's Disease. Cell Mol Gastroenterol Hepatol 20: 101665, Oct 2025.
Yang H, Dungan M, Beyries K, Wang X, Kilpatrick R, Chen B, Oh S, Berkowitz M, Smith D, Koralov SB, Axelrad J, Lengner CJ, Belle N, Bewtra M, Katona BW, Cadwell K.: MAIT cell enrichment in Lynch syndrome is associated with immune surveillance and colorectal cancer risk. bioRxiv Aug 2025.
Cao S, Nguyen KM, Ma K, Tan T, Yao X, Liu TC, Ayoub M, Devi J, Samaan S, Liu Y, Smith R, Silviera ML, Hunt SR, Wise PE, Mutch MG, Glasgow SC, Chapman WC Jr, Cowan ML, Ciorba MA, Colonna M, Deepak P; SPARC IBD Investigators.: Revealing hyperactivated IFN-γ pathways in perianal fistulizing Crohn's disease using single-cell and spatial multi-omics. J Clin Invest 135: e193413, Jul 2025.