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Michael G.S. Shashaty, MD, MSCE

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
5039 W Gates
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-615-5031
BS (Biology)
Georgetown University, 1997.
MD (Medicine)
Vanderbilt University School of Medicine, 2003.
MSCE (Clinical Epidemiology)
Perelman School of Medicine, University of Pennsylvania, 2010.
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Selected Publications

Miano TA, Hennessy S, Yang W, Dunn TG, Weisman AR, Oniyide O, Agyekum RS, Turner AP, Ittner CAG, Anderson BJ, Wilson FP, Townsend R, Reilly JP, Giannini HM, Cosgriff CV, Jones TK, Meyer NJ, Shashaty MGS.: Association of vancomycin plus piperacillin-tazobactam with early changes in creatinine versus cystatin C in critically ill adults: a prospective cohort study. Intensive Care Med Jul 2022.

Pike DP, McGuffee RM, Geerling E, Albert CJ, Hoft DF, Shashaty MGS, Meyer NJ, Pinto AK, Ford DA: Plasmalogen Loss in Sepsis and SARS-CoV-2 Infection. Frontiers in Cell and Developmental Biology 10, Jun 2022.

Mitchell OJL, Dewan M, Wolfe HA, Roberts KJ, Neefe S, Lighthall G, Sands NA, Weissman G, Ginestra J, Shashaty MGS, Schweickert WD, Abella BS: Defining Physiological Decompensation: An Expert Consensus and Retrospective Outcome Validation. Critical Care Explorations 4(4): e0677, Apr 2022 Notes: accepted for publication.

Faust HE, Oniyide O, Wang Y, Forker CM, Dunn T, Yang W, Lanken PN, Sims CA, Yehya N, Christie JD, Meyer NJ, Reilly JP, Mangalmurti NS, Shashaty MGS: Early Plasma Nuclear DNA, Mitochondrial DNA, and Nucleosome Concentrations are Associated with Acute Kidney Injury in Critically Ill Trauma Patients. Critical Care Explorations March 2022 Notes: accepted for publication.

Jones TK, Reilly JP, Anderson BJ, Miano TA, Dunn TG, Weisman AR, Agyekum R, Feng R, Ittner CAG, Shashaty MGS, Meyer NJ.: Elevated Plasma Levels of Matrix Metalloproteinase-3 and Tissue-Inhibitor of Matrix Metalloproteinases-1 Associate With Organ Dysfunction and Mortality in Sepsis. Shock 57: 41-47, Jan 2022.

Amunugama K, Jellinek MJ, Kilroy MP, Albert CJ, Rasi V, Hoft DF, Shashaty MGS, Meyer NJ, Ford DA.: Identification of novel neutrophil very long chain plasmalogen molecular species and their myeloperoxidase mediated oxidation products in human sepsis. Redox Biol 48: 102208, Dec 2021.

Wu J, Ma Z, Raman A, Beckerman P, Dhillon P, Mukhi D, Palmer M, Chen HC, Cohen CR, Dunn T, Reilly J, Meyer N, Shashaty M, Arany Z, Haskó G, Laudanski K, Hung A, Susztak K.: APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis. Immunity 54: 2632-2649, Nov 2021.

Kahn B, Apostolidis SA, Bhatt V, Greenplate AR, Kallish S, LaCava A, Lucas A, Meyer NJ, Negoianu D, Ogdie AR, Shashaty MGS, Takach PA, Zuroff L, Wherry EJ, Anesi GL.: Multisystem Inflammation and Organ Dysfunction After BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccination. Crit Care Explor 3: e0578, Nov 2021.

Farrell C, Miano TA, Griffiths S, Christie JD, Diamond JM, Shashaty MGS: Early post-lung transplant calcineurin inhibitor management varies widely: an international survey. Clinical Transplantation Oct 2021 Notes: Published online.

Vasquez CR, Gupta S, Miano TA, Roche M, Hsu J, Yang W, Holena DN, Reilly JP, Schrauben SJ, Leaf DE, Shashaty MGS; STOP-COVID Investigators.: Identification of Distinct Clinical Subphenotypes in Critically Ill Patients With COVID-19. Chest 160(3): 929-943, Sep 2021.

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Last updated: 08/05/2022
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