faculty photo

Michael G. S. Shashaty, MD, MSCE, FCCM

Associate Professor of Medicine (Pulmonary, Allergy and Critical Care) at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
5038 W Gates
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-615-5031
Education:
BS (Biology)
Georgetown University, 1997.
MD (Medicine)
Vanderbilt University School of Medicine, 2003.
MSCE (Clinical Epidemiology)
Perelman School of Medicine, University of Pennsylvania, 2010.
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Selected Publications

Bennett RM, Housel KC, Jones TK, Giannini HM, Emre G, Esperanza M, Turner A, Ittner C, Shashaty MGS, Feng R, Anderson MR, Weissman GE, Meyer NJ, Christie JD, Reilly JP.: Two Physiologic Latent Classes of Acute Hypoxemic Respiratory Failure in Sepsis Are Distinguished by Lung Mechanics and Gas Exchange. Crit Care Explor 7: e1314, Sep 2025.

Jones TK, Reilly JP, Anderson BJ, Miano TA, Karanam B, Ittner CAG, Shashaty MGS, Feng R, Meyer NJ.: Soluble Fms-Like Tyrosine Kinase-1 Associates With Risk of Acute Respiratory Distress Syndrome and Mortality in Sepsis. Crit Care Explor 7: e1294, Aug 2025.

Ronner L, Giannini HM, Miano TA, Ittner CAG, Turner AP, Dunn TG, Agyekum RS, Dasgupta A, West K, Jones TK, Shashaty MGS, Reilly JP, Meyer NJ.: Parsimonious Subphenotyping Algorithms Perform Differently in Patients With Sepsis and Hematologic Malignancy. Crit Care Med Jul 2025.

Dasgupta A, Jones TK, Giannini H, Bennett R, Emre G, Ittner CAG, Turner A, Esperanza M, Housel K, Miano T, Erlich M, Anderson BJ, Shashaty MGS, Meyer NJ, Reilly JP.: Identifying a unique signature of sepsis in patients with pre-existing cirrhosis. Crit Care 29: 199, May 2025.

Miano TA, Brotman CHW, Scheetz MH, Shashaty MGS.: Effect of Pseudonephrotoxicity on Apparent Acute Kidney Injury Incidence and Severity: A Simulation Study. Clin J Am Soc Nephrol 20: 866-868, Dec 2024.

Miano TA, Zuppa AF, Feng R, Griffiths S, Kalman L, Oyster M, Cantu E, Yang W, Diamond JM, Christie JD, Scheetz MH, Shashaty MGS.: Development and validation of a population pharmacokinetic model to guide perioperative tacrolimus dosing after lung transplantation. JHLT Open 6: 100134, Aug 2024.

Schneider ALC, Ginestra JC, Kerlin MP, Shashaty MGS, Miano TA, Herman DS, Mitchell OJL, Bennett R, Moffett AT, Chandler J, Kalanuria A, Faraji Z, Bishop NS, Schmid B, Chen AT, Bowles KH, Joseph T, Kohn R, Kelz RR, Anesi GL, Kumar M, Friedman AB, Vail E, Meyer NJ, Himes BE, Weissman GE.: The Complete Inpatient Record Using Comprehensive Electronic Data (CIRCE) project: A team-based approach to clinically validated, research-ready electronic health record data. Learn Health Syst 9: e10439, Jun 2024.

Bennett RM, Reilly JP, Diamond JM, Cantu E, Shashaty M, Benvenuto L, Singer JP, Palmer SM, Christie JD, Anderson MR.: Body mass index and mortality following primary graft dysfunction: A Lung Transplant Outcomes Group study. JHLT Open 5: 100107, May 2024.

Diamond JM, Anderson MR, Cantu E, Clausen ES, Shashaty MGS, Kalman L, Oyster M, Crespo MM, Bermudez CA, Benvenuto L, Palmer SM, Snyder LD, Hartwig MG, Wille K, Hage C, McDyer JF, Merlo CA, Shah PD, Orens JB, Dhillon GS, Lama VN, Patel MG, Singer JP, Hachem RR, Michelson AP, Hsu J, Russell Localio A, Christie JD.: Development and validation of primary graft dysfunction predictive algorithm for lung transplant candidates. J Heart Lung Transplant 43(4): 633-641, Apr 2024.

Reilly JP, Shashaty MGS, Miano TA, Giannini HM, Jones TK, Ittner CAG, Christie JD, Meyer NJ.: ABO Histo-Blood Group and the von Willebrand Factor Axis in Severe COVID-19. CHEST Crit Care Dec 2023.

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Last updated: 10/21/2025
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