faculty photo

Richard Aplenc, MD, PhD, MSCE

Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Colket Translational Research Building
Suite 4018
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 267-426-7252
A.B. (Classics)
Princeton University, 1988.

University of Pennsylvania, Post-Baccalaureate Pre-Health Program, 1989.
University of Virginia, 1994.
MSCE (Clinical Epidemiology and Biostatistics)
University of Pennsylvania, 2002.
PhD (Epidemiology)
University of Pennsylvania, 2011.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Pollard JA, Guest E, Alonzo TA, Gerbing RB, Loken MR, Brodersen LE, Kolb EA, Aplenc R, Meshinchi S, Raimondi SC, Hirsch B, Gamis AS: Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in Pediatric KMT2A-Rearranged AML: Results From the Phase III Children's Oncology Group Trial AAML0531. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39(28): 3149-3160, Oct 2021 Notes: doi: 10.1200/JCO.20.03048.

Leahy AB, Newman H, Li Y, Liu H, Myers R, DiNofia A, Dolan JG, Callahan C, Baniewicz D, Devine K, Wray L, Aplenc R, June CH, Grupp SA, Rheingold SR, Maude SL: CD19-targeted chimeric antigen receptor T-cell therapy for CNS relapsed or refractory acute lymphocytic leukaemia: a post-hoc analysis of pooled data from five clinical trials. The Lancet Haematology 8(10): e711-e722, Oct 2021 Notes: doi: 10.1016/S2352-3026(21)00238-6.

Elgarten CW, Wood AC, Li Y, Alonzo TA, Brodersen LE, Gerbing RB, Getz KD, Huang YV, Loken M, Meshinchi S, Pollard JA, Sung L, Woods WG, Kolb EA, Gamis AS, Aplenc R: Outcomes of intensification of induction chemotherapy for children with high-risk acute myeloid leukemia: A report from the Children's Oncology Group. Pediatric blood & cancer Oct 2021 Notes: doi: 10.1002/pbc.29281.

Getz KD, Alonzo TA, Sung L, Meshinchi S, Gerbing RB, Raimondi S, Hirsch B, Loken M, Eidenschink Brodersen L, Kahwash S, Choi J, Kolb EA, Gamis A, Aplenc R: Cytarabine dose reduction in patients with low-risk acute myeloid leukemia: A report from the Children's Oncology Group. Pediatric blood & cancer Sep 2021 Notes: doi: 10.1002/pbc.29313.

Cahen VC, Li Y, Getz KD, Elgarten CW, DiNofia AM, Wilkes JJ, Winestone LE, Huang YV, Miller TP, Gramatges MM, Rabin KR, Fisher BT, Aplenc R, Seif AE: Identifying Relapses and Stem Cell Transplants in Pediatric Acute Lymphoblastic Leukemia Using Administrative Data: Capturing National Outcomes Irrespective of Trial Enrollment. Pediatric blood & cancer 68(9): e28315, Sep 2021 Notes: doi: 10.1002/pbc.28315.

Kerlavage AR, Kirchhoff AC, Guidry Auvil JM, Sharpless NE, Davis KL, Reilly K, Reaman G, Penberthy L, Deapen D, Hwang A, Durbin EB, Gallotto SL, Aplenc R, Volchenboum SL, Heath AP, Aronow BJ, Zhang J, Vaske O, Alonzo TA, Nathan PC, Poynter JN, Armstrong G, Hahn EE, Wernli KJ, Greene C, DiGiovanna J, Resnick AC, Shalley ER, Nadaf S, Kibbe WA: Cancer Informatics for Cancer Centers: Scientific Drivers for Informatics, Data Science, and Care in Pediatric, Adolescent, and Young Adult Cancer. JCO Clinical Cancer Informatics 5: 881-896, Aug 2021 Notes: doi: 10.1200/CCI.21.00040.

Getz KD, Lewey J, Tam V, Corazon Irizarry O, Levine LD, Aplenc R, Arany Z, Schuyler Jones W: Neighborhood education status drives racial disparities in clinical outcomes in PPCM. American Heart Journal 238: 27-32, Aug 2021 Notes: doi: 10.1016/j.ahj.2021.03.013.

Leahy AB, Schwartz LA, Li Y, Reeve BB, Bekelman JE, Aplenc R, Basch EM: Electronic symptom monitoring in pediatric patients hospitalized for chemotherapy. Cancer 127(16): 2980-2989, Aug 2021 Notes: doi: 10.1002/cncr.33617.

Mangum DS, Meyer JA, Mason CC, Shams S, Maese LD, Gardiner JD, Downie JM, Pei D, Cheng C, Gleason A, Luo M, Pui C, Aplenc R, Hunger SP, Loh M, Greaves M, Trede N, Raetz E, Frazer JK, Mullighan CG, Engel ME, Miles RR, Rabin KR, Schiffman JD: Association of Combined Focal 22q11.22 Deletion and IKZF1 Alterations With Outcomes in Childhood Acute Lymphoblastic Leukemia. JAMA Oncology Aug 2021 Notes: doi: 10.1001/jamaoncol.2021.2723.

Ibrahimova A, Winestone LE, Miller TP, Kettler K, Seif AE, Huang Y, Elgarten CW, Myers RM, Fisher BT, Aplenc R, Getz KD: Presentation acuity, induction mortality, and resource utilization in infants with acute leukemia. Pediatric blood & cancer 68(7): e28940, Jul 2021 Notes: doi: 10.1002/pbc.28940.

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Last updated: 10/07/2021
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