faculty photo

Richard Aplenc, MD, PhD, MSCE

Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Colket Translational Research Building
Suite 4018
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 267-426-7252
Education:
A.B. (Classics)
Princeton University, 1988.

University of Pennsylvania, Post-Baccalaureate Pre-Health Program, 1989.
MD
University of Virginia, 1994.
MSCE (Clinical Epidemiology and Biostatistics)
University of Pennsylvania, 2002.
PhD (Epidemiology)
University of Pennsylvania, 2011.
Permanent link
 
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Selected Publications

Getz KD, Alonzo TA, Sung L, Meshinchi S, Gerbing RB, Raimondi S, Hirsch B, Loken M, Brodersen LE, Kahwash S, Choi J, Kolb EA, Gamis A, Aplenc R: Cytarabine dose reduction in patients with low-risk acute myeloid leukemia: A report from the Children's Oncology Group. Pediatric blood & cancer 69(1), Jan 2022 Notes: doi: 10.1002/pbc.29313.

Huang BJ, Smith JL, Wang Y, Taghizadeh K, Leonti AR, Ries RE, Liu Y, Kolekar P, Tarlock K, Gerbing R, Crowgey E, Furlan SN, Shaw TI, Hagiwara K, Wei L, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Farrar JE, Triche T, Alonzo TA, Ma X, Mesinchi S: CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes. Blood Advances | American Society of Hematology 5(23): 4963-4968, Dec 2021 Notes: doi: 10.1182/bloodadvances.2021004965.

Elgarten CW, Wood AC, Li Y, Alonzo TA, Brodersen LE, Gerbing RB, Getz KD, Huang YV, Loken M, Meshinchi S, Pollard JA, Sung L, Woods WG, Kolb EA, Gamis AS, Aplenc R: Outcomes of intensification of induction chemotherapy for children with high-risk acute myeloid leukemia: A report from the Children's Oncology Group. Pediatric blood & cancer 68(12): e29281, Dec 2021 Notes: doi: 10.1002/pbc.29281.

Lamble AJ, Brodersen LE, Alonzo TA, Wang J, Pardo L, Sung L, Cooper TM, Kolb EA, Aplenc R, Tasian SK, Loken MR, Meshinchi S: CD123 Expression Is Associated With High-Risk Disease Characteristics in Childhood Acute Myeloid Leukemia: A Report From the Children's Oncology Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology Dec 2021 Notes: doi: 10.1200/JCO.21.01595.

Congcong L, Glisovic-Aplenc T, Bernt KM, Nestler K, Cesare J, Cao L, Lee H, Fazelinia H, Chinwalla A, Xu Y, Shestova O, Xing Y, Gill S, Li M, Garcia B, Aplenc R: Longitudinal Large-Scale Semiquantitative Proteomic Data Stability Across Multiple Instrument Platforms. Journal of Proteome Research 20(11): 5203-5211, Nov 2021 Notes: doi: 10.1021/acs.jproteome.1c00624.

van Dijk AD, Hoff FW, Qiu Y, Gerbing RB, Gamis AS, Aplenc R, Kolb EA, Alonzo TA, Meshinchi S, Jenkins GN, de Bont ESJM, Kornblau SM, Horton TM: Bortezomib is significantly beneficial for de novo pediatric AML patients with low phosphorylation of the NF-κB subunit RelA. Proteomics: Clinical Applications Page: e2100072, Nov 2021 Notes: doi: 10.1002/prca.202100072.

Rosenfield E, Getz KD, Miller TP, Seif AE, Fisher BT, Burrows E, Ramos MJ, De Leon DD, Aplenc R, Morales KH, Guevara JP: Incidence and risk factors for hypoglycemia during maintenance chemotherapy in pediatric acute lymphoblastic leukemia. Pediatric blood & cancer Page: e29467, Nov 2021 Notes: doi: 10.1002/pbc.29467.

O'Connor MJ, Zhang X, Griffis H, Fisher BT, Getz KD, Li Y, Rossano JW, Lin KY, Burstein DS, Huang Y, Aplenc R: Center Variation in Indication and Short-Term Outcomes after Pediatric Heart Transplantation: Analysis of a Merged United Network for Organ Sharing - Pediatric Health Information System Cohort. Pediatric Cardiology Nov 2021 Notes: doi: 10.1007/s00246-021-02768-x.

Pollard JA, Guest E, Alonzo TA, Gerbing RB, Loken MR, Brodersen LE, Kolb EA, Aplenc R, Meshinchi S, Raimondi SC, Hirsch B, Gamis AS: Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in Pediatric KMT2A-Rearranged AML: Results From the Phase III Children's Oncology Group Trial AAML0531. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 39(28): 3149-3160, Oct 2021 Notes: doi: 10.1200/JCO.20.03048.

Getz KD, Szymczak JE, Li Y, Madding R, Huang YV, Aftandilian C, Arnold SD, Bona KO, Caywood E, Collier AB, Gramatges MM, Henry M, Lotterman C, Maloney K, Mian A, Mody R, Morgan E, Raetz EA, Rubnitz J, Verma A, Winick N, Wilkes JJ, Yu JC, Fisher BT, Aplenc R: Medical Outcomes, Quality of Life, and Family Perceptions for Outpatient vs Inpatient Neutropenia Management After Chemotherapy for Pediatric Acute Myeloid Leukemia. JAMA Network Open 4(10): e2128385, Oct 2021 Notes: doi: 10.1001/jamanetworkopen.2021.28385.

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Last updated: 04/21/2022
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