faculty photo

Sean Hennessy, PharmD, PhD

Professor of Epidemiology in Biostatistics and Epidemiology
Department: Biostatistics and Epidemiology

Contact information
University of Pennsylvania
423 Guardian Drive
803 Blockley Hall
Philadelphia, PA 19104-6021
Office: 215-898-9112
Fax: 215-573-5315
BS (Pharmacy)
Philadelphia College of Pharmacy and Science, 1989.
PharmD (Clinical Pharmacy)
Philadelphia College of Pharmacy and Science, 1990.
MSCE (Clinical Epidemiology)
University of Pennsylvania School of Medicine, 1996.
PhD (Epidemiology with Biostatistics minor)
University of Pennsylvania, 2002.
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Selected Publications

Flannery D, Passarella M, Mukhopadhyay S, Dhudasia M, Gerber J, Lorch S, Hennessy S, Puopolo K: Early childhood antibiotic utilization for infants discharged from the neonatal intensive care unit. Journal of Perinatology 2022 (https://doi.org/10.1038/s41372-022-01380-y).

Shah M, Marmarelis ME, Mamtani R, Hennessy S: Association between survival and very high versus high PD-L1 expression in patients receiving pembrolizumab as first-line treatment for advanced non-small cell lung cancer. Clinical Lung Cancer 2022 (https://doi.org/10.1016/j.cllc.2022.07.003).

Miano TA, Hennessy S, Yang W, Dunn TG, Weisman AR, Oniyide O, Agyekum RS, Turner AP, Ittner CAG, Anderson B, Wilson FP, Townsend R, Giannini HM, Cosgriff CV, Jones TK, Meyer NJ, Shashaty MGS: Association of vancomycin plus piperacillin-tazobactam with early changes in creatinine versus cystatin C in critically ill Adults: a prospective cohort study. Intensive Care Medicine 2022 (https://doi.org/10.1007/s00134-022-06811-0).

Shah M, Hubbard RA, Mamtani R, Marmarelis ME, Hennessy S: Very high PD-L1 Expression as a prognostic indicator of overall survival among Patients with advanced non-small cell lung cancer receiving anti PD-(L)1 monotherapies in routine practice. Pharmacoepidemiology and Drug Safety 2022 (https://doi.org/10.1002/pds.5487).

Miano TA, Wang L, Leonard CE, Brensinger CM, Acton EK, Dawwas DK, Bilker WB, Soprano SE, Nguyen TPP, Woody G, Yu E, Neuman M, Li L, Hennessy S: Identifying clinically relevant drug-drug interactions with methadone and buprenorphine: a translational approach to signal detection. Clinical Pharmacology and Therapeutics 2022 (https://doi.org/10.1002/cpt.2717).

Dhopeshwarkar N, Yang W, Hennessy S, Rhodes JM, Cuker A, Leonard CE: Rate of major bleeding with ibrutinib versus bendamustine-rituximab in chronic lymphocytic leukemia: a population-based cohort study. American Journal of Hematology 2022 (https://doi.org/10.1002/ajh.26632).

Bogar K, Brensinger CM, Hennessy S, Flory JH, Bell ML, Shi C, Bilker WB, Leonard CE: Climate change and ambient temperature extremes: Association with serious hypoglycemia, diabetic ketoacidosis, and sudden cardiac arrest/ventricular arrhythmia in persons with type 2 diabetes. Diabetes Care 2022 (forthcoming) Notes: In press.

Chen C, Hennessy S, Brensinger CM, Acton EK, Bilker WB, Chung S, Dawwas GK, Dublin S, Horn JR, Miano TA, Pham Nguyen TP, Leonard CE: Population-based screening to detect benzodiazepine drug-drug-drug interaction signals associated with unintentional traumatic injury. Scientific Reports 2022 (forthcoming).

Chen C, Hennessy S, Brensinger CM, Bilker WB, Dublin S, Chung S, Horn J, Bogar K, Leonard CE: Antidepressant drug-drug-drug interactions associated with unintentional traumatic injury: Screening for signals in real-world data. Clinical and Translational Science 2022 (forthcoming).

Leonard CE, Brensinger CM, Bilker WB, Soprano SE, Dhopeshwarkar N, Hecht TE, Kasner SE, Nutescu EA, Holbrook A, Carr MJ, Ashcroft DM, Chen C, Hennessy S: Thromboembolic events in users of warfarin treated with dif-ferent skeletal muscle relaxants. Medicina 2022 (forthcoming).

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Last updated: 11/01/2022
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