faculty photo

Sean Hennessy, PharmD, PhD

Professor of Epidemiology in Biostatistics and Epidemiology
Department: Biostatistics and Epidemiology

Contact information
University of Pennsylvania
3600 Civic Center Boulevard
4W-105C
Philadelphia, PA 19104-3413
Office: 215-898-9112
Education
BS (Pharmacy)
Philadelphia College of Pharmacy and Science, 1989.
PharmD (Clinical Pharmacy)
Philadelphia College of Pharmacy and Science, 1990.
MSCE (Clinical Epidemiology)
University of Pennsylvania School of Medicine, 1996.
PhD (Epidemiology with Biostatistics minor)
University of Pennsylvania, 2002.
Permanent link
 
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Selected Publications

Chu PY, Kelly A, Hennessy S, Vajravelu ME, Huang J, Amaral S: GLP-1RA dispensing in youth With type 2 diabetes: 2020 to 2023. Pediatrics Page: e2025071971, 2026.

Hsu Y-C, Thakrar AP, Leonard CE, Lowenstein M, Brensinger CM, Bilker WB, Bogar KF, Hennessy S: Trends in methadone use for pain and opioid use disorder among Medicaid enrollees. JAMA Health Forum 6: e244023, 2025.

Srivastava T, Harris RA, Bettigole C, Zhang H, Brensinger CM, Bogar K, Wang F, Nesoff ED, Bilker WB, Hennessy S: Stimulant overdose prediction model for Medicaid-insured persons. JAMA Health Forum 6: e253489, 2025.

Vo T-T, Ye T, Ertefaie A, Roy S, Flory J, Hennessy S, Vansteelandt S, Small DS: Structural mean models for instrumented difference-in-differences. European Journal of Statistics 18: 5132-55, 2024.

Bonnesen K, Heide-Jørgensen U, Christensen DH, Lash TL, Hennessy S, Matthews A, Pedersen L, Thomsen RW, Schmidt M: Comparative cardiovascular effectiveness of empagliflozin versus dapagliflozin in adults with treated type 2 diabetes: a target trial emulation. Circulation 150: 1401-11, 2024.

Chen C, Miano TA, Brensinger CM, Leonard CE, Bilker WB, Hennessy S: Risk of opioid overdose associated with concomitant use of methadone and statins. Clinical Pharmacology and Therapeutics 117: 421-26, 2024.

Torgersen T, Mezochow AK,Newcomb CW, Carbonari DM, Hennessy S, CT Rentsch, Park LS, Tate JP, Bräu N, Bhattacharya D, Lim JK, Mezzacappa C, Njei B,Roy JA, Taddei TH, Justice AC, Lo Re III V: Rates of severe acute liver injury after hepatotoxic medication initiation in real-world data. JAMA Internal Medicine 184: 943-52, 2024.

Golder S, Medaglio D, O'Connor K, Hennessy S, Gross R, Gonzalez Hernandez G: Reasons for discontinuation or change of selective serotonin reuptake inhibitors in online drug reviews. JAMA Network Open 6: e2323746, 2023.

Steinkamp J, Hecht TWH, Hennessy S, Leonard CE, Shu D, Airan-JCI S: Off-brand: A six-year study of medication brand and generic name usage in a multi-facility academic healthcare system. Journal of Hospital Medicine 18: 812-821, 2023.

Lo Re III V, Dutcher SK, Connolly JF, Perez-Vilar S, Carbonari DM, DeFor TA, Djibo DA, Harrington LB, Hou L, Hennessy S, Hubbard RA, Kempner ME, Kuntz JL, McMahill-Walraven CN, Mosley J, Pawloski PA, Petrone AB, Pishko AM, Rogers Driscoll M, Steiner CA, Zhou Y, Cocoros NM: Risk of admission to hospital with arterial or venous thromboembolism among patients diagnosed in the ambulatory setting with covid- 19 compared with influenza: retrospective cohort study. BMJ Medicine 2: e000421, 2023.

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Last updated: 10/06/2026
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