faculty photo

Sean Hennessy, PharmD, PhD

Professor of Epidemiology in Biostatistics and Epidemiology
Department: Biostatistics and Epidemiology

Contact information
University of Pennsylvania
423 Guardian Drive
803 Blockley Hall
Philadelphia, PA 19104-6021
Office: 215-898-9112
Fax: 215-573-5315
BS (Pharmacy)
Philadelphia College of Pharmacy and Science, 1989.
PharmD (Clinical Pharmacy)
Philadelphia College of Pharmacy and Science, 1990.
MSCE (Clinical Epidemiology)
University of Pennsylvania School of Medicine, 1996.
PhD (Epidemiology with Biostatistics minor)
University of Pennsylvania, 2002.
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Selected Publications

Brumberg K, Ellis DE, Small DS, Hennessy S, Rosenbaum PR: Using natural strata when examining unmeasured biases in an observational study of neurological side effects of antibiotics. Journal of the Royal Statistical Society: Series C 2023 (https://doi.org/10.1093/jrsssc/qlad010).

Shah M, Mamtani R, Marmarelis ME, Hennessy S: Chemoimmunotherapy versus immunotherapy for first line treatment of advanced non-small cell lung 2 cancer with a PD-L1 expression >=50% or >=90% Clinical Lung Cancer 2023 (https://doi.org/10.1016/j.cllc.2023.02.007).

Shu D, Han P, Hennessy S, Miano TA: Robust causal inference of drug-drug interactions. Statistics in Medicine 2023 (https://doi.org/10.1002/sim.9653).

Dhopeshwarkar N, Yang W, Hennessy S, Rhodes JM, Cuker A, Leonard CE: Bleeding with concomitant ibrutinib and oral anticoagulant therapy: a population-based cohort study. American Journal of Hematology 2023 (forthcoming).

Abraham DS, Pham Nguyen TP, Blank LJ, Thibault D, Gray SL, Hennessy S, Leonard CE, Weintraub D, Willis AW : Channeling of new neuropsychiatric drugs—-Impact on safety and effectiveness studies. Neurotherapeutics 2023 (epub ahead of print).

Flannery D, Passarella M, Mukhopadhyay S, Dhudasia M, Gerber J, Lorch S, Hennessy S, Puopolo K: Early childhood antibiotic utilization for infants discharged from the neonatal intensive care unit. Journal of Perinatology 2022 (https://doi.org/10.1038/s41372-022-01380-y).

Shah M, Marmarelis ME, Mamtani R, Hennessy S: Association between survival and very high versus high PD-L1 expression in patients receiving pembrolizumab as first-line treatment for advanced non-small cell lung cancer. Clinical Lung Cancer 2022 (https://doi.org/10.1016/j.cllc.2022.07.003).

Miano TA, Hennessy S, Yang W, Dunn TG, Weisman AR, Oniyide O, Agyekum RS, Turner AP, Ittner CAG, Anderson B, Wilson FP, Townsend R, Giannini HM, Cosgriff CV, Jones TK, Meyer NJ, Shashaty MGS: Association of vancomycin plus piperacillin-tazobactam with early changes in creatinine versus cystatin C in critically ill Adults: a prospective cohort study. Intensive Care Medicine 2022 (https://doi.org/10.1007/s00134-022-06811-0).

Shah M, Hubbard RA, Mamtani R, Marmarelis ME, Hennessy S: Very high PD-L1 Expression as a prognostic indicator of overall survival among Patients with advanced non-small cell lung cancer receiving anti PD-(L)1 monotherapies in routine practice. Pharmacoepidemiology and Drug Safety 2022 (https://doi.org/10.1002/pds.5487).

Miano TA, Wang L, Leonard CE, Brensinger CM, Acton EK, Dawwas DK, Bilker WB, Soprano SE, Nguyen TPP, Woody G, Yu E, Neuman M, Li L, Hennessy S: Identifying clinically relevant drug-drug interactions with methadone and buprenorphine: a translational approach to signal detection. Clinical Pharmacology and Therapeutics 2022 (https://doi.org/10.1002/cpt.2717).

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Last updated: 03/10/2023
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