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Russell Takeshi Shinohara, Ph.D.
50Professor of Biostatistics and Epidemiology
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Department: Biostatistics and Epidemiology
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Graduate Group Affiliations
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Contact information
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Center for Clinical Epidemiology and Biostatistics
41 Department of Biostatistics, Epidemiology and Informatics
23 Perelman School of Medicine
22 University of Pennsylvania
19 217 Blockley Hall
3a 423 Guardian Drive
Philadelphia, PA 19104-6021
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41 Department of Biostatistics, Epidemiology and Informatics
23 Perelman School of Medicine
22 University of Pennsylvania
19 217 Blockley Hall
3a 423 Guardian Drive
Philadelphia, PA 19104-6021
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Office: 215-746-1090
32 Fax: 215-573-1050
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32 Fax: 215-573-1050
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Email:
rshi@pennmedicine.upenn.edu
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rshi@pennmedicine.upenn.edu
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Education:
21 f Honors BSc 27 (Probability and Statistics) c
2a McGill University, 2006.
21 8 MSc 27 (Mathematics and Statistics) c
2a McGill University, 2007.
21 8 PhD 1a (Biostatistics) c
35 The Johns Hopkins University, 2012.
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Permanent link21 f Honors BSc 27 (Probability and Statistics) c
2a McGill University, 2006.
21 8 MSc 27 (Mathematics and Statistics) c
2a McGill University, 2007.
21 8 PhD 1a (Biostatistics) c
35 The Johns Hopkins University, 2012.
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12b Lee JD, Renner B, Nair SM, Nakamura K, Luskin E, Shinohara RT, Reich DS, Solomon AJ, Sicotte NL, Ontaneda D, Sati P: Superior visibility of paramagnetic rim lesions on filtered phase versus SWI. Am J Neuroradiol In press 2026.
28e Scharf A, Cohen JA, Marrie RA, Miller AE, Waubant E, Kilbane M, Luskin E, Azevedo CJ, Dever M, Alvarez E, Calabresi PA, Chahin S, Freeman L, Nakamura K, Longbrake EE, Mowry EM, Oh J, Rodrigues PR, Ramos M, Sotirchos ES, Cutter GR, Kaisey M, Amin M, Toljan K, Illenberger N, Bilello M, Lee J, Maya M, Obusez EC, Schindler MK, Suthiphosuwan S, Ulano A, Shinohara RT, Reich DS, Solomon AJ, Sicotte NL, Sati P, Ontaneda D: Application of the 2024 McDonald criteria in individuals with nonspecific symptoms or incidental imaging findings in a multicenter study. Neurology In press 2026.
16a Lyu X, Brown CA, Duong MT, Fischer EP, McGrew E, Irwin DJ, Dickerson BC, Nasrallah IM, Shinohara RT, Young AL, Yushkevich PA, Das SR, Wolk DA: Uncovering Distinct Spatiotemporal Trajectories of T-N Mismatch. Alzheimer's & Dementia: The Journal of the Alzheimer's Association In press 2026.
10e Prettyman GE, Kales E, Didier P, Savage C, Levinson T, Rosenbaum S, Fernando Viegas de Moraes Leme L, Kable JW, Moore TM, Satterthwaite TD, Davatzikos C, Shinohara RT, Elliott MA, Kohler CG, Gur RC, Gur RE, Calkins ME, Wolf DH 56 : Impaired intrinsic motivation in psychosis risk relates to ventral striatum 69 activation to self-generated reinforcement signals. Schizophr Res. In press 2026.
1a5 Ren Z, Chen A, Puvvula J, Xu Y, Bouche E, Calafat AM, Edmondson AD, Linn KA, Shinohara RT, Ospina M, Percy Z, Vuong AM, Braun JM, Lanphear BP, Yolton K, Cao Q, Cecil KM: Identifying Associations and Key Early Life Exposure Windows for Organophosphate Esters and Adolescent Brain Morphometry in the HOME Study. Environmental Research In press 2026.
201 Laule C, Cohen-Adad J, Witt A, De Luca GC, Granziera C, Keegan BM, Kerbrat A, Klawiter E, Kolind S, O’Grady KP, Oh J, Schilling K, Sivakolundu DK, Smith SA, Tozlu C, Vavasour IM, Bagnato F, Gauthier SA, Mainero C, Alonso-Ortiz E, Bakshi R, Beck ES, Brier MR, Hemond CC, Krieger S, Li DKB, Shinohara RT, Henry RG: Spinal Cord Imaging for Multiple Sclerosis: Advances, Priorities and Opportunities. Multiple Sclerosis Journal In press 2026.
120 Brennan D, Schneider ALC, Shinohara RT, Diaz-Arrastia R, Cook PA, Gee JC, Gugger JJ: Contusions Bias Cortical Thickness Estimates After Traumatic Brain Injury: A TRACK-TBI Study. Neuroimage: Clinical In press 2026.
d5 Hillman N, Weinstein SM, Bagautdinova J, Sun KY, Cieslak M, Salo T, Fan Y, Keller AS, Alexander-Bloch AF, Vandekar SN, Raznahan A, Satterthwaite TD, Shou H, Shinohara RT a6 : Testing for Network Specificity in Brain-Behavior 1 Associations Using Ordinal Dominance Curves 2. Human Brain Mapping In press 2026.
143 Amin M, Toljan K, Daboul L, Nakamura K, Solomon AJ, Sicotte NL, Shinohara RT, Reich DS, Sati P, Ontaneda D: Comparison of central FLAIR hypointensity and central vein sign on FLAIR* in a diagnostic cohort. European Journal of Radiology In press 2026.
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Selected Publications
233 Toljan K, Renner B, Daboul L, Martin ML, Cao Q, O’Donnell CM, Rodrigues P, Derbyshire J, Azevedo CJ, Bar-Or A, Caverzasi E, Calabresi PA, Cree BAC, Freeman L, Henry RG, Longbrake EE, Nakamura K, Oh J, Papinutto N, Pelletier D, Samudralwar RD, Schindler MK, Sotirchos ES, Sicotte NL, Solomon AJ, Shinohara RT, Reich DS, Sati P, Ontaneda D: Diagnostic Performance of Central Vein Sign and Paramagnetic Rim Lesion Integration for Multiple Sclerosis. Multiple Sclerosis Journal In press 2026.12b Lee JD, Renner B, Nair SM, Nakamura K, Luskin E, Shinohara RT, Reich DS, Solomon AJ, Sicotte NL, Ontaneda D, Sati P: Superior visibility of paramagnetic rim lesions on filtered phase versus SWI. Am J Neuroradiol In press 2026.
28e Scharf A, Cohen JA, Marrie RA, Miller AE, Waubant E, Kilbane M, Luskin E, Azevedo CJ, Dever M, Alvarez E, Calabresi PA, Chahin S, Freeman L, Nakamura K, Longbrake EE, Mowry EM, Oh J, Rodrigues PR, Ramos M, Sotirchos ES, Cutter GR, Kaisey M, Amin M, Toljan K, Illenberger N, Bilello M, Lee J, Maya M, Obusez EC, Schindler MK, Suthiphosuwan S, Ulano A, Shinohara RT, Reich DS, Solomon AJ, Sicotte NL, Sati P, Ontaneda D: Application of the 2024 McDonald criteria in individuals with nonspecific symptoms or incidental imaging findings in a multicenter study. Neurology In press 2026.
16a Lyu X, Brown CA, Duong MT, Fischer EP, McGrew E, Irwin DJ, Dickerson BC, Nasrallah IM, Shinohara RT, Young AL, Yushkevich PA, Das SR, Wolk DA: Uncovering Distinct Spatiotemporal Trajectories of T-N Mismatch. Alzheimer's & Dementia: The Journal of the Alzheimer's Association In press 2026.
10e Prettyman GE, Kales E, Didier P, Savage C, Levinson T, Rosenbaum S, Fernando Viegas de Moraes Leme L, Kable JW, Moore TM, Satterthwaite TD, Davatzikos C, Shinohara RT, Elliott MA, Kohler CG, Gur RC, Gur RE, Calkins ME, Wolf DH 56 : Impaired intrinsic motivation in psychosis risk relates to ventral striatum 69 activation to self-generated reinforcement signals. Schizophr Res. In press 2026.
1a5 Ren Z, Chen A, Puvvula J, Xu Y, Bouche E, Calafat AM, Edmondson AD, Linn KA, Shinohara RT, Ospina M, Percy Z, Vuong AM, Braun JM, Lanphear BP, Yolton K, Cao Q, Cecil KM: Identifying Associations and Key Early Life Exposure Windows for Organophosphate Esters and Adolescent Brain Morphometry in the HOME Study. Environmental Research In press 2026.
201 Laule C, Cohen-Adad J, Witt A, De Luca GC, Granziera C, Keegan BM, Kerbrat A, Klawiter E, Kolind S, O’Grady KP, Oh J, Schilling K, Sivakolundu DK, Smith SA, Tozlu C, Vavasour IM, Bagnato F, Gauthier SA, Mainero C, Alonso-Ortiz E, Bakshi R, Beck ES, Brier MR, Hemond CC, Krieger S, Li DKB, Shinohara RT, Henry RG: Spinal Cord Imaging for Multiple Sclerosis: Advances, Priorities and Opportunities. Multiple Sclerosis Journal In press 2026.
120 Brennan D, Schneider ALC, Shinohara RT, Diaz-Arrastia R, Cook PA, Gee JC, Gugger JJ: Contusions Bias Cortical Thickness Estimates After Traumatic Brain Injury: A TRACK-TBI Study. Neuroimage: Clinical In press 2026.
d5 Hillman N, Weinstein SM, Bagautdinova J, Sun KY, Cieslak M, Salo T, Fan Y, Keller AS, Alexander-Bloch AF, Vandekar SN, Raznahan A, Satterthwaite TD, Shou H, Shinohara RT a6 : Testing for Network Specificity in Brain-Behavior 1 Associations Using Ordinal Dominance Curves 2. Human Brain Mapping In press 2026.
143 Amin M, Toljan K, Daboul L, Nakamura K, Solomon AJ, Sicotte NL, Shinohara RT, Reich DS, Sati P, Ontaneda D: Comparison of central FLAIR hypointensity and central vein sign on FLAIR* in a diagnostic cohort. European Journal of Radiology In press 2026.
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