faculty photo

Adam Christian Naj, PhD

Assistant Professor of Epidemiology in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Department: Biostatistics and Epidemiology

Contact information
921 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Office: (215) 746-4180
Fax: (215) 573-1050
Lab: (215) 746-4180
Education:
BA (Biology (Genetics)/Psychology)
University of Chicago, 2000.
PhD (Epidemiology (Human Genetics))
The Johns Hopkins University Bloomberg School of Public Health, 2008.
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Selected Publications

Archer DB, Eissman JM, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Gifford KA; Alzheimer's Disease Neuroimaging Initiative (ADNI); Alzheimer's Disease Genetics Consortium (ADGC); Alzheimer's Disease Sequencing Project (ADSP); Cuccaro ML, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Mayeux RP, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Dumitrescu L, Hohman TJ.: Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease. Alzheimer's & Dementia November 2023 Notes: Online ahead of print.

Eissman JM, Archer DB, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Gifford KA; Alzheimer's Disease Neuroimaging Initiative (ADNI) | Alzheimer's Disease Genetics Consortium (ADGC) | The Alzheimer's Disease Sequencing Project (ADSP); Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Mayeux RP, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Hohman TJ, Dumitrescu L.: Sex-specific genetic architecture of late-life memory performance. Alzheimer's & Dementia November 2023 Notes: Online ahead of print.

Lee WP, Choi SH, Shea MG, Cheng PL, Dombroski BA, Pitsillides AN, Heard-Costa NL, Wang H, Bulekova K, Kuzma AB, Leung YY, Farrell JJ, Lin H, Naj A, Blue EE, Nusetor F, Wang D, Boerwinkle E, Bush WS, Zhang X, De Jager PL, Dupuis J, Farrer LA, Fornage M, Martin E, Pericak-Vance M, Seshadri S, Wijsman EM, Wang LS, Schellenberg GD, Destefano AL, Haines JL, Peloso GM.: Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project. medRxiv September 2023 Notes: Under review at Nature Genetics.

Katsumata Y, Fardo DW, Shade LMP; Alzheimer’s Disease Genetics Consortium; Nelson PT.: LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry. Journal of Neuropathology and Experimental Neurology 82: 760-768, August 2023.

Li L, Wu Q, Lundin SK, Naj AC, Gur RC, Rascovsky K, Wolk DA, Tao C, Chen Y: Investigating drug repurposing for the prevention of Alzheimer’s disease and related dementias using electronic health records in the University of Pennsylvania Health System. Alzheimer's Association International Conference (AAIC), Amsterdam, Netherlands July 2023 Notes: Poster presentation.

Janve VA, Archer DB, Eissman JM, Durant A, Mukherjee S, Lee ML, Choi S-E, Scollard P, Trittschuh EH, Mez JB, Bush WS, Fardo DW, Buckley RF, Mormino EC, Kunkle BW, Naj AC, Gifford KA, Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang L-S, Schellenberg GD, Haines JL, Jefferson AL, Kukull WA, Albert MS, Keene CD, Saykin AJ, Sperling RA, Mayeux R, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Dumitrescu L, Hohman TJ, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Genetics Consortium (ADGC), Alzheimer's Disease Sequencing Project (ADSP): Both clinically informed and brain region agnostic approaches identify neuroimaging derived phenotypes associated with genetically regulated gene expression of late-onset Alzheimer's disease genes. Alzheimer's Association International Conference (AAIC), Amsterdam, Netherlands July 2023 Notes: Poster presentation.

Janve VA, Archer DB, Eissman JM, Durant A, Mukherjee S, Lee ML, Choi S-E, Scollard P, Trittschuh EH, Mez JB, Bush WS, Fardo DW, Buckley RF, Mormino EC, Kunkle BW, Naj AC, Gifford KA, Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang L-S, Schellenberg GD, Haines JL, Jefferson AL, Kukull WA, Albert MS, Keene CD, Saykin AJ, Sperling RA, Mayeux R, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Dumitrescu L, Hohman TJ, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Genetics Consortium (ADGC), Alzheimer's Disease Sequencing Project (ADSP): Predicted gene expression identifies novel tissue-specific gene predictors of memory performance in older adults. Alzheimer's Association International Conference (AAIC), Amsterdam, Netherlands July 2023 Notes: Poster presentation.

Walters S, Eissman JM, Mukherjee S, Lee ML, Choi S-E, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Gifford KA, The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Genetics Consortium (ADGC), The Alzheimer's Disease Sequencing Project (ADSP), Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang L-S, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Albert MS, Johnson SC, Engelman CD, Mayeux R, Vardarajan BN, Hohman TJ, Dumitrescu L: Genetic predictors of multiple cognitive domains within ancestry groups in older adults. Alzheimer's Association International Conference (AAIC), Amsterdam, Netherlands July 2023 Notes: Poster presentation.

Eissman JM, Walters S, Mukherjee S, Lee ML, Choi S-E, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Gifford KA, The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Genetics Consortium (ADGC), The Alzheimer's Disease Sequencing Project (ADSP), Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang L-S, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Albert MS, Johnson SC, Engelman CD, Mayeux R, Vardarajan BN, Crane PK, Hohman TJ, Dumitrescu L: Sex-specific genetic architecture of multiple domains of cognition among older adults. Alzheimer's Association International Conference (AAIC), Amsterdam, Netherlands July 2023 Notes: Poster presentation.

Li YJ, Nuytemans K, La JO, Jiang R, Slifer SH, Sun S, Naj A, Gao XR, Martin ER.: Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses. Alzheimer's & Dementia 19(7): 3148-3157, July 2023.

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Last updated: 12/05/2023
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