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Daniel S Herman, MD, PhD
8fAssistant Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
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Department: Pathology and Laboratory Medicine
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Graduate Group Affiliations
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Contact information
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3700 Hamilton Walk, Richards Medical Building BB01
Philadelphia, PA 19104
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Philadelphia, PA 19104
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Office: 215-573-4765
32 Fax: 215.662.7529
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32 Fax: 215.662.7529
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Publications
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Education:
21 7 BS 2b (Bachelor of Science in Biology) c
3e Massachusetts Institute of Technology, 2004.
21 8 PhD 30 (Doctorate of Philosophy in Genetics) c
54 Harvard Medical School, Division of Medical Sciences (MSTP), 2011.
21 7 MD 22 (Doctorate of Medicine) c
56 Harvard Medical School, Health Sciences and Technology (MSTP), 2013.
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Permanent link21 7 BS 2b (Bachelor of Science in Biology) c
3e Massachusetts Institute of Technology, 2004.
21 8 PhD 30 (Doctorate of Philosophy in Genetics) c
54 Harvard Medical School, Division of Medical Sciences (MSTP), 2011.
21 7 MD 22 (Doctorate of Medicine) c
56 Harvard Medical School, Health Sciences and Technology (MSTP), 2013.
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f3 Herman DS, Rhoads DD, Schulz WL, Durant TJS: Artificial Intelligence and Mapping a New Direction in Laboratory Medicine: A Review. Clin Chem 67 (11): 1466 - 82, Nov 2021.
122 Daniel S Herman, Eseraldo Toro, Ezra G. Baraban, Adam Bagg, Ping Wang: Falsely Increased Plasma Lactate Dehydrogenase without Hemolysis Following Transport Through Pneumatic Tube System. JALM 4(3): 433 - 38, Nov 2019.
17b Herman DS, Smith C, Liu C, Vaughn CP, Palaniappan S, Pritchard CC, Shirts BH: Efficient Detection of Copy Number Mutations in PMS2 Exons with Close Homologs: Detection of Copy Number Variants in 3' PMS2 Exons. J Mol Diagn 20(4): 512-521, Jul 2018 Notes: doi: 10.1016/j.jmoldx.2018.03.010. Epub 2018 May 22.
2e1 Roberts AM*, Ware JS*, Herman DS*, Schafer S, Baksi J, Bick AG, Buchan RJ, Walsh R, John S, Wilkinson S, Mazzarotto F, Felkin LE, Gong S, MacArthur JA, Cunningham F, Flannick J, Gabriel SB, Altshuler DM, Macdonald PS, Heinig M, Keogh AM, Hayward CS, Banner NR, Pennell DJ, O'Regan DP, San TR, de Marvao A, Dawes TJ, Gulati A, Birks EJ, Yacoub MH, Radke M, Gotthardt M, Wilson JG, O'Donnell CJ, Prasad SK, Barton PJ, Fatkin D, Hubner N, Seidman JG, Seidman CE, Cook SA.: Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease. Sci Transl Med 7(270): 270ra6, Jan 2015 Notes: * Authors did equal work on article. 36 doi: 10.1126/scitranslmed.3010134.
18f Herman DS, Ranjitkar P, Yamaguchi D, Grenache DG, Greene DN.: Endogenous alkaline phosphatase interference in cardiac troponin I and other sensitive chemiluminescence immunoassays that use alkaline phosphatase activity for signal amplification. Clin Biochem 49(15): 1118-1121, Oct 2016 Notes: Epub ahead of Print 2016/June 16.
1de Bick AG, Flannick J, Ito K, Cheng S, Ramachandran VS, Parfenov MG, Herman DS, DePalma SR, Gupta N, Gabriel S, Funke BH, Rehm HL, Benjamin E, Aragam J, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, O’Donnell C, Wilson JG, Altshuler DL, Hirschhorn JN, Seidman JG, Seidman C.: Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study Cohorts. Am J Hum Gen 91(3): 513-9, Sept 2012.
1ed Herman DS, Lam L, Taylor MR, Wang L, Teekakirikul P, Christodoulou D, Conner L, DePalma SR, McDonough B, Sparks E, Teodorescu DL, Cirino AL, Banner NR, Pennell DJ, Graw S, Merlo M, Di Lenarda A, Sinagra G, Bos JM, Ackerman MJ, Mitchell RN, Murry CE, Lakdawala NK, Ho CY, Barton PJ, Cook SA, Mestroni L, Seidman JG, Seidman CE.: Truncations of Titin Causing Dilated Cardiomyopathy. N Engl J Med. 366(7): 619-28, Feb 2012.
142 Herman DS, Hovingh GK, Iartchouk O, Rehm HL, Kucherlapati R, Seidman JG, Seidman CE.: Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection. Nat Methods 6(7): 507-10, Jul 2009 Notes: E-published ahead of print 2009, June 21. 2d doi: 10.1038/nmeth.1343.
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Selected Publications
196 Lingjiao Zhang, Xiruo Ding, Yanyuan Ma, Naveen Muthu, Imran Ajmal, Jason H. Moore, Daniel S. Herman*, Jinbo Chen*; * Co-corresponding: A maximum likelihood approach to electronic health record phenotyping using positive and unlabeled patients. J Am Med Inform Assoc. 27(1): 119 - 26, Jan 2020 Notes: https://arxiv.org/abs/1902.10060.f3 Herman DS, Rhoads DD, Schulz WL, Durant TJS: Artificial Intelligence and Mapping a New Direction in Laboratory Medicine: A Review. Clin Chem 67 (11): 1466 - 82, Nov 2021.
122 Daniel S Herman, Eseraldo Toro, Ezra G. Baraban, Adam Bagg, Ping Wang: Falsely Increased Plasma Lactate Dehydrogenase without Hemolysis Following Transport Through Pneumatic Tube System. JALM 4(3): 433 - 38, Nov 2019.
17b Herman DS, Smith C, Liu C, Vaughn CP, Palaniappan S, Pritchard CC, Shirts BH: Efficient Detection of Copy Number Mutations in PMS2 Exons with Close Homologs: Detection of Copy Number Variants in 3' PMS2 Exons. J Mol Diagn 20(4): 512-521, Jul 2018 Notes: doi: 10.1016/j.jmoldx.2018.03.010. Epub 2018 May 22.
2e1 Roberts AM*, Ware JS*, Herman DS*, Schafer S, Baksi J, Bick AG, Buchan RJ, Walsh R, John S, Wilkinson S, Mazzarotto F, Felkin LE, Gong S, MacArthur JA, Cunningham F, Flannick J, Gabriel SB, Altshuler DM, Macdonald PS, Heinig M, Keogh AM, Hayward CS, Banner NR, Pennell DJ, O'Regan DP, San TR, de Marvao A, Dawes TJ, Gulati A, Birks EJ, Yacoub MH, Radke M, Gotthardt M, Wilson JG, O'Donnell CJ, Prasad SK, Barton PJ, Fatkin D, Hubner N, Seidman JG, Seidman CE, Cook SA.: Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease. Sci Transl Med 7(270): 270ra6, Jan 2015 Notes: * Authors did equal work on article. 36 doi: 10.1126/scitranslmed.3010134.
18f Herman DS, Ranjitkar P, Yamaguchi D, Grenache DG, Greene DN.: Endogenous alkaline phosphatase interference in cardiac troponin I and other sensitive chemiluminescence immunoassays that use alkaline phosphatase activity for signal amplification. Clin Biochem 49(15): 1118-1121, Oct 2016 Notes: Epub ahead of Print 2016/June 16.
1de Bick AG, Flannick J, Ito K, Cheng S, Ramachandran VS, Parfenov MG, Herman DS, DePalma SR, Gupta N, Gabriel S, Funke BH, Rehm HL, Benjamin E, Aragam J, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, O’Donnell C, Wilson JG, Altshuler DL, Hirschhorn JN, Seidman JG, Seidman C.: Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study Cohorts. Am J Hum Gen 91(3): 513-9, Sept 2012.
1ed Herman DS, Lam L, Taylor MR, Wang L, Teekakirikul P, Christodoulou D, Conner L, DePalma SR, McDonough B, Sparks E, Teodorescu DL, Cirino AL, Banner NR, Pennell DJ, Graw S, Merlo M, Di Lenarda A, Sinagra G, Bos JM, Ackerman MJ, Mitchell RN, Murry CE, Lakdawala NK, Ho CY, Barton PJ, Cook SA, Mestroni L, Seidman JG, Seidman CE.: Truncations of Titin Causing Dilated Cardiomyopathy. N Engl J Med. 366(7): 619-28, Feb 2012.
142 Herman DS, Hovingh GK, Iartchouk O, Rehm HL, Kucherlapati R, Seidman JG, Seidman CE.: Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection. Nat Methods 6(7): 507-10, Jul 2009 Notes: E-published ahead of print 2009, June 21. 2d doi: 10.1038/nmeth.1343.
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