Department of Sleep Medicine

Sleep Faculty
faculty photo

Ron C Anafi, M.D., Ph.D.

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Instructor A in Medicine, University of Pennsylvania Perelman School of Medicine, Department of Medicine
Faculty Scholar, Penn Institute for Bioinformatics
Department: Medicine

Contact information
Translational Research Laboratories, Suite 2100
125 South 31st Street
Philadelphia, PA 19104
B.S.E. (Biomedical engineering and philosophy)
Tulane University, 1995.
Ph.D. (Applied mechanics)
University of Minnesota, 2002.
University of Minnesota, 2004.
Post-Graduate Training
Intern in Medicine, University of Vermont/Fletcher Allen Hospital, 2004-2005.
Resident in Medicine, University of Vermont/Fletcher Allen Hospital, 2005-2007.
Research Fellow (part-time), Vermont Lung Center , 2007-2008.
Fellowship in Sleep Medicine, Hospital of the University of Pennsylvania, 2008-2009.
Research fellow, Center for Sleep and Circadian Neurobiology, University of Pennsylvania, 2009-2011.
American Board of Internal Medicine - Internal Medicine, 2007.
American Board of Internal Medicine – Sleep Medicine, 2009.
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Selected Publications

Paul R and Anafi RC: Insomnia in Patients with Comorbid Medical Problems. Clinical Handbook of Insomnia, 3rd ed. Attarian, H (eds.). Springer International Publishing, Page: 199-219, October 2016.

Wu G, Anafi RC, Hughes ME, Kornacker K, Hogenesch JB: MetaCycle: an integrated R package to evaluate periodicity in large scale data. Bioinformatics 32(21): 3351-3353, Nov 2016.

Zhang Ray, Podtelezhnikov Alexei A, Hogenesch John B, Anafi Ron C: Discovering Biology in Periodic Data through Phase Set Enrichment Analysis (PSEA). Journal of biological rhythms 31(3): 244-57, Jun 2016.

Arnardottir Erna S, Nikonova Elena V, Shockley Keith R, Podtelezhnikov Alexei A, Anafi Ron C, Tanis Keith Q, Maislin Greg, Stone David J, Renger John J, Winrow Christopher J, Pack Allan I: Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation. Sleep 37(10): 1589-600, Oct 2014.

Anafi RC, Hogenesch JB, and Kim J: Big-data mining through circular component analysis reveals diurnal oscillations in the human transcriptome. Sleep 38: A72, 2015 Notes: Poster presentation.

Anafi Ron C, Lee Yool, Sato Trey K, Venkataraman Anand, Ramanathan Chidambaram, Kavakli Ibrahim H, Hughes Michael E, Baggs Julie E, Growe Jacqueline, Liu Andrew C, Kim Junhyong, Hogenesch John B: Machine learning helps identify CHRONO as a circadian clock component. PLoS biology 12(4): e1001840, Apr 2014.

Deckard Anastasia, Anafi Ron C, Hogenesch John B, Haase Steven B, Harer John: Design and analysis of large-scale biological rhythm studies: a comparison of algorithms for detecting periodic signals in biological data. Bioinformatics (Oxford, England) 29(24): 3174-80, Dec 2013.

Anafi Ron C, Pellegrino Renata, Shockley Keith R, Romer Micah, Tufik Sergio, Pack Allan I: Sleep is not just for the brain: transcriptional responses to sleep in peripheral tissues. BMC genomics 14: 362, May 2013.

Anafi R C, Wilson T A: Airway stability and heterogeneity in the constricted lung. Journal of applied physiology (Bethesda, Md. : 1985) 91(3): 1185-92, Sep 2001.

Anafi RC, Beck KC, Wilson TA: Impedance, gas mixing, and bimodal ventilation in constricted lungs. Journal of Applied Physiology 94(3): 1003-1011, Mar 2003.

Anafi RC, Wilson TA: Empirical model for dynamic force-length behavior of airway smooth muscle. Journal of Applied Physiology 92(2): 455-460, Feb 2002.

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Last updated: 03/20/2017
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