Department of Genetics, University of Pennsylvania

What we do


Our research focuses on how genotypes produce phenotypes and how they vary and evolve. We are particularly interested in identifying and experimentally characterizing functional human non-coding sequence variation. We aim to understand the mechanisms through which non-coding variants function, with an emphasis on understanding the mechanisms underlying complex human disease. We leverage a combination of high throughput experimental and computational approaches. We are currently focused on massively parallelizing assays that interrogate non-coding DNA function and applying these approaches to the fine-mapping of the causal variants underlying human disease.

We are currently hiring staff and trainees with experience and interest in genomic molecular biology and bioinformatic analysis. Postdoctoral applicants in particular are encouraged to contact Casey directly to enquire about opportunities.